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    SLIT3 slit guidance ligand 3 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 703950, updated on 17-Aug-2024

    Summary

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    Official Symbol
    SLIT3provided by VGNC
    Official Full Name
    slit guidance ligand 3provided by VGNC
    Primary source
    VGNC:VGNC:77645
    See related
    Ensembl:ENSMMUG00000017087
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See SLIT3 in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    37
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 6 NC_041759.1 (166063118..166702887, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 6 NC_027898.1 (166917652..167566158, complement)

    Chromosome 6 - NC_041759.1Genomic Context describing neighboring genes Neighboring gene microRNA mir-103-1 Neighboring gene pantothenate kinase 3 Neighboring gene ribosomal protein L32-like Neighboring gene microRNA mir-218-2 Neighboring gene uncharacterized LOC106999029 Neighboring gene uncharacterized LOC114678968 Neighboring gene U6 spliceosomal RNA Neighboring gene spindle apparatus coiled-coil protein 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables Roundabout binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables heparin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in axon guidance IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative chemotaxis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    slit homolog 3 protein
    Names
    slit homolog 3 protein-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041759.1 Reference Mmul_10 Primary Assembly

      Range
      166063118..166702887 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015141360.2 → XP_014996846.2  slit homolog 3 protein isoform X1

      UniProtKB/TrEMBL
      A0A5F7ZVD5
      Related
      ENSMMUP00000069128.1, ENSMMUT00000092408.1
      Conserved Domains (12) summary
      PRK15370
      Location:255 → 536
      PRK15370; E3 ubiquitin-protein ligase SlrP; Provisional
      TIGR00864
      Location:636 → 714
      PCC; polycystin cation channel protein
      smart00013
      Location:725 → 756
      LRRNT; Leucine rich repeat N-terminal domain
      smart00082
      Location:857 → 906
      LRRCT; Leucine rich repeat C-terminal domain
      COG4886
      Location:62 → 220
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      cd00054
      Location:1074 → 1110
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      sd00033
      Location:64 → 86
      LRR_RI; leucine-rich repeat [structural motif]
      pfam02210
      Location:1188 → 1314
      Laminin_G_2; Laminin G domain
      cl15307
      Location:215 → 250
      TPKR_C2; Tyrosine-protein kinase receptor C2 Ig-like domain
      pfam00008
      Location:1123 → 1153
      EGF; EGF-like domain
      pfam13855
      Location:776 → 835
      LRR_8; Leucine rich repeat
      cl21545
      Location:1466 → 1521
      GHB_like; Glycoprotein hormone beta chain homologues

    2. XM_028849906.1 → XP_028705739.1  slit homolog 3 protein isoform X2

      UniProtKB/TrEMBL
      A0A5F7ZVD5, F7HJ55
      Related
      ENSMMUP00000022488.4, ENSMMUT00000024030.4
      Conserved Domains (11) summary
      PRK15370
      Location:111 → 392
      PRK15370; E3 ubiquitin-protein ligase SlrP; Provisional
      TIGR00864
      Location:492 → 570
      PCC; polycystin cation channel protein
      smart00013
      Location:581 → 612
      LRRNT; Leucine rich repeat N-terminal domain
      smart00082
      Location:713 → 762
      LRRCT; Leucine rich repeat C-terminal domain
      COG4886
      Location:599 → 725
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      cd00054
      Location:930 → 966
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      sd00033
      Location:390 → 414
      LRR_RI; leucine-rich repeat [structural motif]
      pfam02210
      Location:1044 → 1170
      Laminin_G_2; Laminin G domain
      pfam00008
      Location:979 → 1009
      EGF; EGF-like domain
      pfam13855
      Location:632 → 691
      LRR_8; Leucine rich repeat
      cl21545
      Location:1322 → 1377
      GHB_like; Glycoprotein hormone beta chain homologues
    Nucleotide Protein
    Heading Accession and Version

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