TRIM37 tripartite motif containing 37 [Macaca mulatta (Rhesus monkey)] - Gene

Summary

Official Symbol: TRIM37provided by VGNC
Official Full Name: tripartite motif containing 37provided by VGNC
Primary source: VGNC:VGNC:79966
See related: Ensembl:ENSMMUG00000011443
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Macaca mulatta
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 16

Exon count:: 27

Annotation release	Status	Assembly	Chr	Location
103	current	Mmul_10 (GCF_003339765.1)	16	NC_041769.1 (37690215..37814632)
102	previous assembly	Mmul_8.0.1 (GCF_000772875.2)	16	NC_027908.1 (30531986..30655988)

Chromosome 16 - NC_041769.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Markers

RH11893 (e-PCR)
- UniSTS:75531

D17S1670 (e-PCR)
- UniSTS:16410

G20499 (e-PCR)
- UniSTS:2352

A005U07 (e-PCR)
- UniSTS:2353

G42202 (e-PCR)
- UniSTS:93305

G42231 (e-PCR)
- UniSTS:93334

D17S1389E (e-PCR)
- UniSTS:150442

RH91179 (e-PCR)
- UniSTS:92332

PPM1E__5569 (e-PCR)
- UniSTS:463823

D17S1449E (e-PCR)
- UniSTS:150489

A007E14 (e-PCR)
- UniSTS:57333

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables tumor necrosis factor receptor binding	IEA Inferred from Electronic Annotation more info	PubMed
enables ubiquitin protein ligase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables ubiquitin protein ligase binding	IEA Inferred from Electronic Annotation more info	PubMed
enables zinc ion binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in negative regulation of NF-kappaB transcription factor activity	IEA Inferred from Electronic Annotation more info	PubMed
involved_in negative regulation of centriole replication	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of NF-kappaB transcription factor activity	IEA Inferred from Electronic Annotation more info	PubMed
involved_in protein autoubiquitination	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in aggresome	IEA Inferred from Electronic Annotation more info	PubMed
located_in peroxisome	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: E3 ubiquitin-protein ligase TRIM37

NP_001245019.1

EC 2.3.2.27

XP_014974595.1

EC 2.3.2.27

XP_014974596.1

EC 2.3.2.27

XP_014974597.1

EC 2.3.2.27

XP_014974598.1

EC 2.3.2.27

XP_014974599.1

EC 2.3.2.27

XP_014974600.1

EC 2.3.2.27

XP_014974601.1

EC 2.3.2.27

XP_014974603.1

EC 2.3.2.27

XP_014974606.1

EC 2.3.2.27

XP_028691402.1

EC 2.3.2.27

XP_028691404.1

EC 2.3.2.27

XP_028691405.1

EC 2.3.2.27

XP_028691406.1

EC 2.3.2.27

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001258090.1 → NP_001245019.1 E3 ubiquitin-protein ligase TRIM37

See identical proteins and their annotated locations for NP_001245019.1

Status: PROVISIONAL

Source sequence(s)

JU475677

UniProtKB/TrEMBL

F7HQA2, G7NHY2

Related

ENSMMUP00000034760.1, ENSMMUT00000041747.3

Conserved Domains (4) summary

smart00502
Location:132 → 254

BBC; B-Box C-terminal domain

cd00162
Location:15 → 58

RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...

cd03773
Location:273 → 406

MATH_TRIM37; Tripartite motif containing protein 37 (TRIM37) family, MATH domain; TRIM37 is a peroxisomal protein and is a member of the tripartite motif (TRIM) protein subfamily, also known as the RING-B-box-coiled-coil (RBCC) subfamily of zinc-finger proteins. ...

pfam00643
Location:90 → 132

zf-B_box; B-box zinc finger

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

NC_041769.1 Reference Mmul_10 Primary Assembly

Range

37690215..37814632

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_015119117.2 → XP_014974603.1 E3 ubiquitin-protein ligase TRIM37 isoform X10

UniProtKB/TrEMBL

F7HQA2, G7NHY2

Related

ENSMMUP00000015011.2, ENSMMUT00000016018.4

Conserved Domains (4) summary

smart00502
Location:132 → 254

BBC; B-Box C-terminal domain

cd00162
Location:15 → 58

RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...

cd03773
Location:273 → 406

MATH_TRIM37; Tripartite motif containing protein 37 (TRIM37) family, MATH domain; TRIM37 is a peroxisomal protein and is a member of the tripartite motif (TRIM) protein subfamily, also known as the RING-B-box-coiled-coil (RBCC) subfamily of zinc-finger proteins. ...

pfam00643
Location:90 → 132

zf-B_box; B-box zinc finger
XM_015119112.2 → XP_014974598.1 E3 ubiquitin-protein ligase TRIM37 isoform X5

UniProtKB/TrEMBL

G7NHY2

Conserved Domains (4) summary

smart00502
Location:132 → 254

BBC; B-Box C-terminal domain

cd00162
Location:15 → 58

RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...

cd03773
Location:273 → 406

MATH_TRIM37; Tripartite motif containing protein 37 (TRIM37) family, MATH domain; TRIM37 is a peroxisomal protein and is a member of the tripartite motif (TRIM) protein subfamily, also known as the RING-B-box-coiled-coil (RBCC) subfamily of zinc-finger proteins. ...

pfam00643
Location:90 → 132

zf-B_box; B-box zinc finger
XM_028835573.1 → XP_028691406.1 E3 ubiquitin-protein ligase TRIM37 isoform X13

Conserved Domains (1) summary

cd03773
Location:28 → 161

MATH_TRIM37; Tripartite motif containing protein 37 (TRIM37) family, MATH domain; TRIM37 is a peroxisomal protein and is a member of the tripartite motif (TRIM) protein subfamily, also known as the RING-B-box-coiled-coil (RBCC) subfamily of zinc-finger proteins. ...
XM_028835571.1 → XP_028691404.1 E3 ubiquitin-protein ligase TRIM37 isoform X9

UniProtKB/TrEMBL

G7NHY2

Conserved Domains (4) summary

smart00502
Location:132 → 254

BBC; B-Box C-terminal domain

cd03773
Location:273 → 406

MATH_TRIM37; Tripartite motif containing protein 37 (TRIM37) family, MATH domain; TRIM37 is a peroxisomal protein and is a member of the tripartite motif (TRIM) protein subfamily, also known as the RING-B-box-coiled-coil (RBCC) subfamily of zinc-finger proteins. ...

cd16619
Location:13 → 55

mRING-HC-C4C4_TRIM37_C-VIII; Modified RING finger, HC subclass (C4C4-type), found in tripartite motif-containing protein 37 (TRIM37) and similar proteins

cd19779
Location:93 → 132

Bbox2_TRIM37_C-VIII; B-box-type 2 zinc finger found in tripartite motif-containing protein 37 (TRIM37) and similar proteins
XM_015119111.2 → XP_014974597.1 E3 ubiquitin-protein ligase TRIM37 isoform X4

UniProtKB/TrEMBL

A0A1D5RA42

Conserved Domains (4) summary

smart00502
Location:158 → 280

BBC; B-Box C-terminal domain

cd03773
Location:299 → 432

MATH_TRIM37; Tripartite motif containing protein 37 (TRIM37) family, MATH domain; TRIM37 is a peroxisomal protein and is a member of the tripartite motif (TRIM) protein subfamily, also known as the RING-B-box-coiled-coil (RBCC) subfamily of zinc-finger proteins. ...

cd16619
Location:39 → 81

mRING-HC-C4C4_TRIM37_C-VIII; Modified RING finger, HC subclass (C4C4-type), found in tripartite motif-containing protein 37 (TRIM37) and similar proteins

cd19779
Location:119 → 158

Bbox2_TRIM37_C-VIII; B-box-type 2 zinc finger found in tripartite motif-containing protein 37 (TRIM37) and similar proteins
XM_015119114.2 → XP_014974600.1 E3 ubiquitin-protein ligase TRIM37 isoform X7

UniProtKB/TrEMBL

A0A1D5RA42

Conserved Domains (4) summary

smart00502
Location:158 → 280

BBC; B-Box C-terminal domain

cd00162
Location:41 → 84

RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...

cd03773
Location:299 → 432

MATH_TRIM37; Tripartite motif containing protein 37 (TRIM37) family, MATH domain; TRIM37 is a peroxisomal protein and is a member of the tripartite motif (TRIM) protein subfamily, also known as the RING-B-box-coiled-coil (RBCC) subfamily of zinc-finger proteins. ...

pfam00643
Location:116 → 158

zf-B_box; B-box zinc finger
XM_015119109.2 → XP_014974595.1 E3 ubiquitin-protein ligase TRIM37 isoform X1

UniProtKB/TrEMBL

A0A1D5RA42

Conserved Domains (4) summary

smart00502
Location:158 → 280

BBC; B-Box C-terminal domain

cd00162
Location:41 → 84

RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...

cd03773
Location:299 → 432

MATH_TRIM37; Tripartite motif containing protein 37 (TRIM37) family, MATH domain; TRIM37 is a peroxisomal protein and is a member of the tripartite motif (TRIM) protein subfamily, also known as the RING-B-box-coiled-coil (RBCC) subfamily of zinc-finger proteins. ...

pfam00643
Location:116 → 158

zf-B_box; B-box zinc finger
XM_015119110.2 → XP_014974596.1 E3 ubiquitin-protein ligase TRIM37 isoform X2

UniProtKB/TrEMBL

A0A1D5RA42

Conserved Domains (4) summary

smart00502
Location:158 → 280

BBC; B-Box C-terminal domain

cd00162
Location:41 → 84

RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...

cd03773
Location:299 → 432

MATH_TRIM37; Tripartite motif containing protein 37 (TRIM37) family, MATH domain; TRIM37 is a peroxisomal protein and is a member of the tripartite motif (TRIM) protein subfamily, also known as the RING-B-box-coiled-coil (RBCC) subfamily of zinc-finger proteins. ...

pfam00643
Location:116 → 158

zf-B_box; B-box zinc finger
XM_015119115.2 → XP_014974601.1 E3 ubiquitin-protein ligase TRIM37 isoform X8

UniProtKB/TrEMBL

A0A1D5RIK5

Conserved Domains (4) summary

smart00502
Location:158 → 280

BBC; B-Box C-terminal domain

cd00162
Location:41 → 84

RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...

cd03773
Location:299 → 432

MATH_TRIM37; Tripartite motif containing protein 37 (TRIM37) family, MATH domain; TRIM37 is a peroxisomal protein and is a member of the tripartite motif (TRIM) protein subfamily, also known as the RING-B-box-coiled-coil (RBCC) subfamily of zinc-finger proteins. ...

pfam00643
Location:116 → 158

zf-B_box; B-box zinc finger
XM_015119120.2 → XP_014974606.1 E3 ubiquitin-protein ligase TRIM37 isoform X12

UniProtKB/TrEMBL

A0A1D5RIK5

Related

ENSMMUP00000060149.2, ENSMMUT00000069632.2

Conserved Domains (5) summary

smart00502
Location:132 → 254

BBC; B-Box C-terminal domain

cd00162
Location:15 → 58

RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...

cd03773
Location:273 → 406

MATH_TRIM37; Tripartite motif containing protein 37 (TRIM37) family, MATH domain; TRIM37 is a peroxisomal protein and is a member of the tripartite motif (TRIM) protein subfamily, also known as the RING-B-box-coiled-coil (RBCC) subfamily of zinc-finger proteins. ...

pfam00643
Location:90 → 132

zf-B_box; B-box zinc finger

pfam15768
Location:839 → 925

DUF4697; Domain of unknown function (DUF4697)
XM_028835569.1 → XP_028691402.1 E3 ubiquitin-protein ligase TRIM37 isoform X3

UniProtKB/TrEMBL

A0A1D5RA42

Conserved Domains (4) summary

smart00502
Location:158 → 280

BBC; B-Box C-terminal domain

cd03773
Location:299 → 432

MATH_TRIM37; Tripartite motif containing protein 37 (TRIM37) family, MATH domain; TRIM37 is a peroxisomal protein and is a member of the tripartite motif (TRIM) protein subfamily, also known as the RING-B-box-coiled-coil (RBCC) subfamily of zinc-finger proteins. ...

cd16619
Location:39 → 81

mRING-HC-C4C4_TRIM37_C-VIII; Modified RING finger, HC subclass (C4C4-type), found in tripartite motif-containing protein 37 (TRIM37) and similar proteins

cd19779
Location:119 → 158

Bbox2_TRIM37_C-VIII; B-box-type 2 zinc finger found in tripartite motif-containing protein 37 (TRIM37) and similar proteins
XM_015119113.2 → XP_014974599.1 E3 ubiquitin-protein ligase TRIM37 isoform X6

UniProtKB/TrEMBL

A0A1D5RA42

Conserved Domains (4) summary

smart00502
Location:158 → 280

BBC; B-Box C-terminal domain

cd00162
Location:41 → 84

RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...

cd03773
Location:299 → 432

MATH_TRIM37; Tripartite motif containing protein 37 (TRIM37) family, MATH domain; TRIM37 is a peroxisomal protein and is a member of the tripartite motif (TRIM) protein subfamily, also known as the RING-B-box-coiled-coil (RBCC) subfamily of zinc-finger proteins. ...

pfam00643
Location:116 → 158

zf-B_box; B-box zinc finger
XM_028835572.1 → XP_028691405.1 E3 ubiquitin-protein ligase TRIM37 isoform X11

UniProtKB/TrEMBL

A0A1D5RIK5

Conserved Domains (4) summary

smart00502
Location:158 → 280

BBC; B-Box C-terminal domain

smart00336
Location:117 → 158

BBOX; B-Box-type zinc finger

cd03773
Location:299 → 432

MATH_TRIM37; Tripartite motif containing protein 37 (TRIM37) family, MATH domain; TRIM37 is a peroxisomal protein and is a member of the tripartite motif (TRIM) protein subfamily, also known as the RING-B-box-coiled-coil (RBCC) subfamily of zinc-finger proteins. ...

cd16619
Location:39 → 81

mRING-HC-C4C4_TRIM37_C-VIII; Modified RING finger, HC subclass (C4C4-type), found in tripartite motif-containing protein 37 (TRIM37) and similar proteins