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    KYNU kynureninase [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 705179, updated on 17-Aug-2024

    Summary

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    Official Symbol
    KYNUprovided by VGNC
    Official Full Name
    kynureninaseprovided by VGNC
    Primary source
    VGNC:VGNC:74223
    See related
    Ensembl:ENSMMUG00000021330
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See KYNU in Genome Data Viewer
    Location:
    chromosome: 12
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 12 NC_041765.1 (30037561..30201955)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 12 NC_027904.1 (29286597..29451285)

    Chromosome 12 - NC_041765.1Genomic Context describing neighboring genes Neighboring gene LDL receptor related protein 1B Neighboring gene transcription factor BTF3 pseudogene Neighboring gene RNA polymerase I-specific transcription initiation factor RRN3 pseudogene Neighboring gene uncharacterized LOC114671323 Neighboring gene Rho GTPase activating protein 15 Neighboring gene uncharacterized LOC106992567

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables kynureninase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables pyridoxal phosphate binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in NAD biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in anthranilate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in tryptophan catabolic process to kynurenine IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    kynureninase

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041765.1 Reference Mmul_10 Primary Assembly

      Range
      30037561..30201955
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015110049.2 → XP_014965535.1  kynureninase isoform X1

      UniProtKB/TrEMBL
      A0A1D5QJX6, F6URB1, G7N811
      Related
      ENSMMUP00000048349.1, ENSMMUT00000070341.2
      Conserved Domains (2) summary
      TIGR01814
      Location:30 → 459
      kynureninase; kynureninase
      cl18945
      Location:24 → 462
      AAT_I; Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the ...

    2. XM_028830673.1 → XP_028686506.1  kynureninase isoform X2

      Conserved Domains (1) summary
      TIGR01814
      Location:30 → 301
      kynureninase
    Nucleotide Protein
    Heading Accession and Version

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