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    PRKD2 protein kinase D2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 716736, updated on 17-Aug-2024

    Summary

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    Official Symbol
    PRKD2provided by VGNC
    Official Full Name
    protein kinase D2provided by VGNC
    Primary source
    VGNC:VGNC:76273
    See related
    Ensembl:ENSMMUG00000017927
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See PRKD2 in Genome Data Viewer
    Location:
    chromosome: 19
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 19 NC_041772.1 (46683310..46726984, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 19 NC_027911.1 (42007605..42054486, complement)

    Chromosome 19 - NC_041772.1Genomic Context describing neighboring genes Neighboring gene G protein subunit gamma 8 Neighboring gene dishevelled binding antagonist of beta catenin 3 Neighboring gene striatin 4 Neighboring gene fukutin related protein Neighboring gene solute carrier family 1 member 5

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Deficiency of PRKD2 triggers hyperinsulinemia and metabolic disorders. Xiao Y, et al. Nat Commun, 2018 May 22. PMID 29789568, Free PMC Article
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    serine/threonine-protein kinase D2
    Names
    serine/threonine-protein kinase D2-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041772.1 Reference Mmul_10 Primary Assembly

      Range
      46683310..46726984 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015124318.2 → XP_014979804.2  serine/threonine-protein kinase D2 isoform X1

      UniProtKB/TrEMBL
      F6Z935, F7ES71, H9YZ65
      Related
      ENSMMUP00000023568.4, ENSMMUT00000025191.4
      Conserved Domains (4) summary
      cd00029
      Location:265 → 314
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
      cd01239
      Location:391 → 511
      PH_PKD; Protein kinase D (PKD/PKCmu) pleckstrin homology (PH) domain
      cd14082
      Location:547 → 806
      STKc_PKD; Catalytic domain of the Serine/Threonine kinase, Protein Kinase D
      pfam00130
      Location:139 → 188
      C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)

    2. XM_015124319.2 → XP_014979805.2  serine/threonine-protein kinase D2 isoform X1

      UniProtKB/TrEMBL
      F6Z935, F7ES71, H9YZ65
      Related
      ENSMMUP00000031557.3, ENSMMUT00000038459.3
      Conserved Domains (4) summary
      cd00029
      Location:265 → 314
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
      cd01239
      Location:391 → 511
      PH_PKD; Protein kinase D (PKD/PKCmu) pleckstrin homology (PH) domain
      cd14082
      Location:547 → 806
      STKc_PKD; Catalytic domain of the Serine/Threonine kinase, Protein Kinase D
      pfam00130
      Location:139 → 188
      C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)

    3. XM_015124320.2 → XP_014979806.1  serine/threonine-protein kinase D2 isoform X2

      Conserved Domains (4) summary
      cd01239
      Location:234 → 354
      PH_PKD; Protein kinase D (PKD/PKCmu) pleckstrin homology (PH) domain
      cd14082
      Location:390 → 649
      STKc_PKD; Catalytic domain of the Serine/Threonine kinase, Protein Kinase D
      cd20843
      Location:97 → 174
      C1_PKD2_rpt2; second protein kinase C conserved region 1 (C1 domain) found in protein kinase D2 (PKD2) and similar proteins
      cl00040
      Location:1 → 44
      C1; protein kinase C conserved region 1 (C1 domain) superfamily
    Nucleotide Protein
    Heading Accession and Version

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