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    GCKR glucokinase regulator [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 701431, updated on 17-Aug-2024

    Summary

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    Official Symbol
    GCKRprovided by VGNC
    Official Full Name
    glucokinase regulatorprovided by VGNC
    Primary source
    VGNC:VGNC:72902
    Locus tag
    EGK_05172
    See related
    Ensembl:ENSMMUG00000005102
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See GCKR in Genome Data Viewer
    Location:
    chromosome: 13
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 13 NC_041766.1 (81431611..81454787, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 13 NC_027905.1 (27793304..27816477)

    Chromosome 13 - NC_041766.1Genomic Context describing neighboring genes Neighboring gene zinc finger protein 512 Neighboring gene SPATA31 subfamily H member 1 Neighboring gene uncharacterized LOC114671747 Neighboring gene fibronectin type III domain containing 4 Neighboring gene intraflagellar transport 172 Neighboring gene U6 spliceosomal RNA

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables carbohydrate binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables enzyme binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables enzyme inhibitor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables fructose-6-phosphate binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in carbohydrate derivative metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in glucose homeostasis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of glucokinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in response to fructose IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    glucokinase regulatory protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041766.1 Reference Mmul_10 Primary Assembly

      Range
      81431611..81454787 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001098190.4 → XP_001098190.2  glucokinase regulatory protein isoform X1

      UniProtKB/TrEMBL
      F7BYJ8, G7N9P7
      Related
      ENSMMUP00000006765.3, ENSMMUT00000007199.4
      Conserved Domains (2) summary
      PRK05441
      Location:30 → 273
      murQ; N-acetylmuramic acid-6-phosphate etherase; Reviewed
      cl00389
      Location:293 → 541
      SIS; SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars.

    2. XM_028831833.1 → XP_028687666.1  glucokinase regulatory protein isoform X2

      Conserved Domains (2) summary
      PRK05441
      Location:30 → 273
      murQ; N-acetylmuramic acid-6-phosphate etherase; Reviewed
      cl00389
      Location:293 → 366
      SIS; SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars.
    Nucleotide Protein
    Heading Accession and Version

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