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    XRCC5 X-ray repair cross complementing 5 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 574279, updated on 17-Aug-2024

    Summary

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    Official Symbol
    XRCC5provided by VGNC
    Official Full Name
    X-ray repair cross complementing 5provided by VGNC
    Primary source
    VGNC:VGNC:99422
    See related
    Ensembl:ENSMMUG00000001927
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See XRCC5 in Genome Data Viewer
    Location:
    chromosome: 12
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 12 NC_041765.1 (103486510..103584718)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 12 NC_027904.1 (98192894..98291039)

    Chromosome 12 - NC_041765.1Genomic Context describing neighboring genes Neighboring gene peroxisomal trans-2-enoyl-CoA reductase Neighboring gene transmembrane protein 169 Neighboring gene membrane associated ring-CH-type finger 4 Neighboring gene uncharacterized LOC106992720 Neighboring gene SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1 Neighboring gene chromobox protein homolog 3-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Elevated gene expression levels distinguish human from non-human primate brains. Cáceres M, et al. Proc Natl Acad Sci U S A, 2003 Oct 28. PMID 14557539, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA helicase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables damaged DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables double-stranded DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables telomeric DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in DNA recombination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cellular response to X-ray IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cellular response to gamma radiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in double-strand break repair via nonhomologous end joining IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in telomere maintenance IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of Ku70:Ku80 complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    X-ray repair cross-complementing protein 5
    Names
    Ku autoantigen
    X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
    X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining; Ku autoantigen, 80kDa)
    NP_001244295.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001257366.1 → NP_001244295.1  X-ray repair cross-complementing protein 5

      See identical proteins and their annotated locations for NP_001244295.1

      Status: PROVISIONAL

      Source sequence(s)
      JU336264
      UniProtKB/TrEMBL
      G7N8V1, H9FZF8
      Related
      ENSMMUP00000002581.4, ENSMMUT00000002733.4
      Conserved Domains (3) summary
      cd00873
      Location:244 → 543
      KU80; Ku-core domain, Ku80 subfamily; Ku80 is a subunit of the Ku protein, which plays a key role in multiple nuclear processes such as DNA repair, chromosome maintenance, transcription regulation, and V(D)J recombination. The mechanism underlying the ...
      pfam03731
      Location:9 → 244
      Ku_N; Ku70/Ku80 N-terminal alpha/beta domain
      pfam08785
      Location:593 → 705
      Ku_PK_bind; Ku C terminal domain like

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041765.1 Reference Mmul_10 Primary Assembly

      Range
      103486510..103584718
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

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