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    ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 705287, updated on 17-Aug-2024

    Summary

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    Official Symbol
    ENPP2provided by VGNC
    Official Full Name
    ectonucleotide pyrophosphatase/phosphodiesterase 2provided by VGNC
    Primary source
    VGNC:VGNC:72223
    Locus tag
    EGK_19232
    See related
    Ensembl:ENSMMUG00000004903
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See ENPP2 in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    28
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 8 NC_041761.1 (119813760..119938121, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 8 NC_027900.1 (118737114..118859376, complement)

    Chromosome 8 - NC_041761.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106999915 Neighboring gene cellular communication network factor 3 Neighboring gene small nucleolar RNA SNORD55/SNORD39 Neighboring gene TATA-box binding protein associated factor 2 Neighboring gene DNA replication and sister chromatid cohesion 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables alkylglycerophosphoethanolamine phosphodiesterase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables lysophospholipase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables phosphodiesterase I activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables polysaccharide binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables scavenger receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in immune response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in phosphatidylcholine catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ectonucleotide pyrophosphatase/phosphodiesterase family member 2
    Names
    ectonucleotide pyrophosphatase/phosphodiesterase 2 (autotaxin)
    XP_001093656.2
    XP_002805517.1
    XP_015001404.2
    XP_015001405.2
    XP_015001406.2
    XP_015001408.1
    XP_028708716.1
    XP_028708717.1
    XP_028708718.1
    XP_028708719.1
    XP_028708720.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041761.1 Reference Mmul_10 Primary Assembly

      Range
      119813760..119938121 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015145918.2 → XP_015001404.2  ectonucleotide pyrophosphatase/phosphodiesterase family member 2 isoform X5

      UniProtKB/TrEMBL
      F7CJD6, I0FSJ4
      Related
      ENSMMUP00000006514.3, ENSMMUT00000006925.4
      Conserved Domains (3) summary
      smart00201
      Location:51 → 94
      SO; Somatomedin B -like domains
      smart00477
      Location:636 → 866
      NUC; DNA/RNA non-specific endonuclease
      pfam01663
      Location:162 → 474
      Phosphodiest; Type I phosphodiesterase / nucleotide pyrophosphatase

    2. XM_015145919.2 → XP_015001405.2  ectonucleotide pyrophosphatase/phosphodiesterase family member 2 isoform X6

      UniProtKB/TrEMBL
      I0FSJ4
      Conserved Domains (3) summary
      smart00201
      Location:51 → 94
      SO; Somatomedin B -like domains
      smart00477
      Location:632 → 862
      NUC; DNA/RNA non-specific endonuclease
      pfam01663
      Location:162 → 474
      Phosphodiest; Type I phosphodiesterase / nucleotide pyrophosphatase

    3. XM_015145920.2 → XP_015001406.2  ectonucleotide pyrophosphatase/phosphodiesterase family member 2 isoform X7

      UniProtKB/TrEMBL
      I0FSJ4
      Conserved Domains (3) summary
      smart00201
      Location:51 → 94
      SO; Somatomedin B -like domains
      smart00477
      Location:611 → 841
      NUC; DNA/RNA non-specific endonuclease
      pfam01663
      Location:162 → 474
      Phosphodiest; Type I phosphodiesterase / nucleotide pyrophosphatase

    4. XM_028852886.1 → XP_028708719.1  ectonucleotide pyrophosphatase/phosphodiesterase family member 2 isoform X4

      UniProtKB/TrEMBL
      I0FSJ4
      Conserved Domains (3) summary
      smart00201
      Location:51 → 94
      SO; Somatomedin B -like domains
      smart00477
      Location:659 → 889
      NUC; DNA/RNA non-specific endonuclease
      pfam01663
      Location:162 → 526
      Phosphodiest; Type I phosphodiesterase / nucleotide pyrophosphatase

    5. XM_028852884.1 → XP_028708717.1  ectonucleotide pyrophosphatase/phosphodiesterase family member 2 isoform X2

      UniProtKB/TrEMBL
      F6YGP1
      Conserved Domains (3) summary
      smart00201
      Location:51 → 94
      SO; Somatomedin B -like domains
      smart00477
      Location:684 → 914
      NUC; DNA/RNA non-specific endonuclease
      pfam01663
      Location:162 → 526
      Phosphodiest; Type I phosphodiesterase / nucleotide pyrophosphatase

    6. XM_028852885.1 → XP_028708718.1  ectonucleotide pyrophosphatase/phosphodiesterase family member 2 isoform X3

      UniProtKB/TrEMBL
      I0FSJ4
      Related
      ENSMMUP00000053594.2, ENSMMUT00000071773.2
      Conserved Domains (3) summary
      smart00201
      Location:51 → 94
      SO; Somatomedin B -like domains
      smart00477
      Location:663 → 893
      NUC; DNA/RNA non-specific endonuclease
      pfam01663
      Location:162 → 526
      Phosphodiest; Type I phosphodiesterase / nucleotide pyrophosphatase

    7. XM_028852883.1 → XP_028708716.1  ectonucleotide pyrophosphatase/phosphodiesterase family member 2 isoform X1

      UniProtKB/TrEMBL
      F6YGP1
      Related
      ENSMMUP00000031973.3, ENSMMUT00000038891.3
      Conserved Domains (3) summary
      smart00201
      Location:51 → 94
      SO; Somatomedin B -like domains
      smart00477
      Location:688 → 918
      NUC; DNA/RNA non-specific endonuclease
      pfam01663
      Location:162 → 526
      Phosphodiest; Type I phosphodiesterase / nucleotide pyrophosphatase

    8. XM_001093656.4 → XP_001093656.2  ectonucleotide pyrophosphatase/phosphodiesterase family member 2 isoform X11

      See identical proteins and their annotated locations for XP_001093656.2

      UniProtKB/TrEMBL
      I0FJB5, I0FSJ4
      Conserved Domains (3) summary
      smart00201
      Location:55 → 98
      SO; Somatomedin B -like domains
      smart00477
      Location:615 → 845
      NUC; DNA/RNA non-specific endonuclease
      pfam01663
      Location:166 → 478
      Phosphodiest; Type I phosphodiesterase / nucleotide pyrophosphatase

    9. XM_015145922.2 → XP_015001408.1  ectonucleotide pyrophosphatase/phosphodiesterase family member 2 isoform X10

      UniProtKB/TrEMBL
      I0FSJ4
      Conserved Domains (3) summary
      smart00201
      Location:55 → 98
      SO; Somatomedin B -like domains
      smart00477
      Location:640 → 870
      NUC; DNA/RNA non-specific endonuclease
      pfam01663
      Location:166 → 478
      Phosphodiest; Type I phosphodiesterase / nucleotide pyrophosphatase

    10. XM_002805471.3 → XP_002805517.1  ectonucleotide pyrophosphatase/phosphodiesterase family member 2 isoform X9

      See identical proteins and their annotated locations for XP_002805517.1

      UniProtKB/TrEMBL
      G7N009, I0FSJ4
      Conserved Domains (3) summary
      smart00201
      Location:55 → 98
      SO; Somatomedin B -like domains
      smart00477
      Location:667 → 897
      NUC; DNA/RNA non-specific endonuclease
      pfam01663
      Location:166 → 530
      Phosphodiest; Type I phosphodiesterase / nucleotide pyrophosphatase

    11. XM_028852887.1 → XP_028708720.1  ectonucleotide pyrophosphatase/phosphodiesterase family member 2 isoform X8

      UniProtKB/TrEMBL
      F7CJD1, I0FSJ4
      Related
      ENSMMUP00000006516.4, ENSMMUT00000006927.4
      Conserved Domains (3) summary
      smart00201
      Location:55 → 98
      SO; Somatomedin B -like domains
      smart00477
      Location:692 → 922
      NUC; DNA/RNA non-specific endonuclease
      pfam01663
      Location:166 → 530
      Phosphodiest; Type I phosphodiesterase / nucleotide pyrophosphatase
    Nucleotide Protein
    Heading Accession and Version

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