GNRH1 gonadotropin releasing hormone 1 [Macaca mulatta (Rhesus monkey)] - Gene

Summary

Official Symbol: GNRH1provided by VGNC
Official Full Name: gonadotropin releasing hormone 1provided by VGNC
Primary source: VGNC:VGNC:73102
Locus tag: EGK_18784
See related: Ensembl:ENSMMUG00000029018
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Macaca mulatta
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Also known as: GNRH; LHRH
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 8

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
103	current	Mmul_10 (GCF_003339765.1)	8	NC_041761.1 (25694876..25698785, complement)
102	previous assembly	Mmul_8.0.1 (GCF_000772875.2)	8	NC_027900.1 (25452541..25459886, complement)

Chromosome 8 - NC_041761.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

findings report the changes in inhibin-alpha subunit gene expression in the corpus luteum is regulated by LH; results suggest a possible multiple crosstalk of Wnt, cAMP, and SF-1 in the regulation of luteal inhibin secretion
Title: Luteinizing hormone regulates inhibin-α subunit expression through multiple signaling pathways involving steroidogenic factor-1 and beta-catenin in the macaque corpus luteum.
Estradiol(E2) induces a rapid excitatory effect on primate LHRH neurons, and this rapid action of E2 appears to be mediated, in part, through GPR30.
Title: Involvement of G protein-coupled receptor 30 (GPR30) in rapid action of estrogen in primate LHRH neurons.
Posterior hypothalamic lesion animals had elevated LHRH levels and higher evening glutamate levels after lesions, whereas LHRH changes did not occur in sham/controls until later.
Title: An increase in in vivo release of LHRH and precocious puberty by posterior hypothalamic lesions in female rhesus monkeys (Macaca mulatta).

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General gene information

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Markers

NoName (e-PCR)
- UniSTS:482389

D8S1916 (e-PCR)
- UniSTS:54113

SHGC-31262 (e-PCR)
- UniSTS:72821

WI-18854 (e-PCR)
- UniSTS:68265

GNRH1 (e-PCR)
- UniSTS:479990

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables gonadotropin hormone-releasing hormone activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in multicellular organism development	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in extracellular region	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: progonadoliberin-1

Names: gonadotropin-releasing hormone 1 (luteinizing-releasing hormone); luteinizing hormone-releasing hormone; progonadoliberin I; progonadoliberin-1 preproprotein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.