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    EHMT2 euchromatic histone lysine methyltransferase 2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 715824, updated on 17-Aug-2024

    Summary

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    Official Symbol
    EHMT2provided by VGNC
    Official Full Name
    euchromatic histone lysine methyltransferase 2provided by VGNC
    Primary source
    VGNC:VGNC:72041
    See related
    Ensembl:ENSMMUG00000011679
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See EHMT2 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    28
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 4 NC_041757.1 (137600135..137618823)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 4 NC_027896.1 (32759618..32778197, complement)

    Chromosome 4 - NC_041757.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106997898 Neighboring gene zinc finger and BTB domain containing 12 Neighboring gene solute carrier family 44 member 4 Neighboring gene neuraminidase 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables histone methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables p53 binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein-lysine N-methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    histone-lysine N-methyltransferase EHMT2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041757.1 Reference Mmul_10 Primary Assembly

      Range
      137600135..137618823
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015136010.2 → XP_014991496.2  histone-lysine N-methyltransferase EHMT2 isoform X5

      UniProtKB/TrEMBL
      F7HEP1, G7MRL1
      Related
      ENSMMUP00000015332.4, ENSMMUT00000016362.4
      Conserved Domains (6) summary
      smart00468
      Location:922 → 1021
      PreSET; N-terminal to some SET domains
      smart00317
      Location:1037 → 1159
      SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
      COG0666
      Location:622 → 820
      ANKYR; Ankyrin repeat [Signal transduction mechanisms]
      TIGR00927
      Location:235 → 326
      2A1904; K+-dependent Na+/Ca+ exchanger
      sd00045
      Location:784 → 814
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:721 → 814
      Ank_2; Ankyrin repeats (3 copies)

    2. XM_015136012.2 → XP_014991498.2  histone-lysine N-methyltransferase EHMT2 isoform X7

      UniProtKB/TrEMBL
      A0A1D5R677, G7MRL1
      Related
      ENSMMUP00000055815.2, ENSMMUT00000060738.2
      Conserved Domains (6) summary
      smart00468
      Location:888 → 987
      PreSET; N-terminal to some SET domains
      smart00317
      Location:1003 → 1125
      SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
      COG0666
      Location:588 → 786
      ANKYR; Ankyrin repeat [Signal transduction mechanisms]
      TIGR00927
      Location:235 → 326
      2A1904; K+-dependent Na+/Ca+ exchanger
      sd00045
      Location:750 → 780
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:687 → 780
      Ank_2; Ankyrin repeats (3 copies)

    3. XM_015136009.2 → XP_014991495.2  histone-lysine N-methyltransferase EHMT2 isoform X8

      UniProtKB/TrEMBL
      G7MRL1
      Conserved Domains (6) summary
      smart00468
      Location:929 → 1028
      PreSET; N-terminal to some SET domains
      smart00317
      Location:1044 → 1166
      SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
      COG0666
      Location:622 → 818
      ANKYR; Ankyrin repeat [Signal transduction mechanisms]
      TIGR00927
      Location:235 → 326
      2A1904; K+-dependent Na+/Ca+ exchanger
      sd00045
      Location:685 → 714
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:721 → 814
      Ank_2; Ankyrin repeats (3 copies)

    4. XM_015136004.2 → XP_014991490.2  histone-lysine N-methyltransferase EHMT2 isoform X1

      UniProtKB/TrEMBL
      G7MRL1
      Conserved Domains (7) summary
      smart00468
      Location:986 → 1085
      PreSET; N-terminal to some SET domains
      smart00317
      Location:1101 → 1223
      SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
      PHA03247
      Location:5 → 261
      PHA03247; large tegument protein UL36; Provisional
      COG0666
      Location:679 → 875
      ANKYR; Ankyrin repeat [Signal transduction mechanisms]
      TIGR00927
      Location:292 → 383
      2A1904; K+-dependent Na+/Ca+ exchanger
      sd00045
      Location:742 → 771
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:778 → 871
      Ank_2; Ankyrin repeats (3 copies)

    5. XM_015136007.2 → XP_014991493.2  histone-lysine N-methyltransferase EHMT2 isoform X3

      UniProtKB/TrEMBL
      G7MRL1
      Conserved Domains (7) summary
      smart00468
      Location:952 → 1051
      PreSET; N-terminal to some SET domains
      smart00317
      Location:1067 → 1189
      SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
      PHA03247
      Location:5 → 261
      PHA03247; large tegument protein UL36; Provisional
      COG0666
      Location:645 → 841
      ANKYR; Ankyrin repeat [Signal transduction mechanisms]
      TIGR00927
      Location:292 → 383
      2A1904; K+-dependent Na+/Ca+ exchanger
      sd00045
      Location:708 → 737
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:744 → 837
      Ank_2; Ankyrin repeats (3 copies)

    6. XM_015136011.2 → XP_014991497.2  histone-lysine N-methyltransferase EHMT2 isoform X6

      UniProtKB/TrEMBL
      G7MRL1
      Conserved Domains (6) summary
      smart00468
      Location:913 → 1012
      PreSET; N-terminal to some SET domains
      smart00317
      Location:1028 → 1150
      SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
      COG0666
      Location:606 → 802
      ANKYR; Ankyrin repeat [Signal transduction mechanisms]
      TIGR00927
      Location:219 → 310
      2A1904; K+-dependent Na+/Ca+ exchanger
      sd00045
      Location:669 → 698
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:705 → 798
      Ank_2; Ankyrin repeats (3 copies)

    7. XM_015136005.2 → XP_014991491.2  histone-lysine N-methyltransferase EHMT2 isoform X2

      UniProtKB/TrEMBL
      A0A1D5Q3J0, G7MRL1
      Related
      ENSMMUP00000042602.2, ENSMMUT00000076078.2
      Conserved Domains (7) summary
      smart00468
      Location:979 → 1078
      PreSET; N-terminal to some SET domains
      smart00317
      Location:1094 → 1216
      SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
      PHA03247
      Location:5 → 261
      PHA03247; large tegument protein UL36; Provisional
      COG0666
      Location:679 → 877
      ANKYR; Ankyrin repeat [Signal transduction mechanisms]
      TIGR00927
      Location:292 → 383
      2A1904; K+-dependent Na+/Ca+ exchanger
      sd00045
      Location:841 → 871
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:778 → 871
      Ank_2; Ankyrin repeats (3 copies)

    8. XM_015136008.2 → XP_014991494.2  histone-lysine N-methyltransferase EHMT2 isoform X4

      UniProtKB/TrEMBL
      G7MRL1
      Conserved Domains (7) summary
      smart00468
      Location:945 → 1044
      PreSET; N-terminal to some SET domains
      smart00317
      Location:1060 → 1182
      SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
      PHA03247
      Location:5 → 261
      PHA03247; large tegument protein UL36; Provisional
      COG0666
      Location:645 → 843
      ANKYR; Ankyrin repeat [Signal transduction mechanisms]
      TIGR00927
      Location:292 → 383
      2A1904; K+-dependent Na+/Ca+ exchanger
      sd00045
      Location:807 → 837
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:744 → 837
      Ank_2; Ankyrin repeats (3 copies)
    Nucleotide Protein
    Heading Accession and Version

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