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    SMG1 SMG1 nonsense mediated mRNA decay associated PI3K related kinase [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 693542, updated on 17-Aug-2024

    Summary

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    Official Symbol
    SMG1provided by VGNC
    Official Full Name
    SMG1 nonsense mediated mRNA decay associated PI3K related kinaseprovided by VGNC
    Primary source
    VGNC:VGNC:99591
    See related
    Ensembl:ENSMMUG00000022441
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See SMG1 in Genome Data Viewer
    Location:
    chromosome: 20
    Exon count:
    64
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 20 NC_041773.1 (17647677..17759777, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 20 NC_027912.1 (17961999..18074948, complement)

    Chromosome 20 - NC_041773.1Genomic Context describing neighboring genes Neighboring gene ribosomal protein S15a Neighboring gene ARL6 interacting reticulophagy regulator 1 Neighboring gene small nucleolar RNA U13 Neighboring gene histone chaperone ASF1-like Neighboring gene U6 spliceosomal RNA Neighboring gene transmembrane channel like 7 Neighboring gene uncharacterized LOC114674480 Neighboring gene coenzyme Q7, hydroxylase

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in DNA damage checkpoint signaling IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of TORC1 signaling IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in nuclear-transcribed mRNA catabolic process, nonsense-mediated decay IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in telomere maintenance IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    serine/threonine-protein kinase SMG1
    Names
    serine/threonine-protein kinase SMG1-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041773.1 Reference Mmul_10 Primary Assembly

      Range
      17647677..17759777 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015125711.2 → XP_014981197.1  serine/threonine-protein kinase SMG1 isoform X2

      UniProtKB/TrEMBL
      H9F9J1
      Conserved Domains (4) summary
      cd05170
      Location:2120 → 2453
      PIKKc_SMG1; Catalytic domain of Suppressor of Morphogenetic effect on Genitalia-1
      pfam02260
      Location:3657 → 3686
      FATC; FATC domain
      pfam15785
      Location:630 → 1241
      SMG1; Serine/threonine-protein kinase smg-1
      pfam17229
      Location:31 → 139
      DUF5303; Region of unknown function (DUF5303)

    2. XM_015125710.2 → XP_014981196.1  serine/threonine-protein kinase SMG1 isoform X1

      UniProtKB/TrEMBL
      H9F9J1
      Conserved Domains (4) summary
      cd05170
      Location:2120 → 2453
      PIKKc_SMG1; Catalytic domain of Suppressor of Morphogenetic effect on Genitalia-1
      pfam02260
      Location:3658 → 3687
      FATC; FATC domain
      pfam15785
      Location:630 → 1241
      SMG1; Serine/threonine-protein kinase smg-1
      pfam17229
      Location:31 → 139
      DUF5303; Region of unknown function (DUF5303)

    3. XM_015125715.2 → XP_014981201.1  serine/threonine-protein kinase SMG1 isoform X4

      UniProtKB/TrEMBL
      A0A5F7ZLC3, H9F9J1
      Related
      ENSMMUP00000065979.1, ENSMMUT00000083643.1
      Conserved Domains (4) summary
      cd05170
      Location:2120 → 2425
      PIKKc_SMG1; Catalytic domain of Suppressor of Morphogenetic effect on Genitalia-1
      pfam02260
      Location:3630 → 3659
      FATC; FATC domain
      pfam15785
      Location:630 → 1241
      SMG1; Serine/threonine-protein kinase smg-1
      pfam17229
      Location:31 → 139
      DUF5303; Region of unknown function (DUF5303)

    4. XM_015125714.2 → XP_014981200.1  serine/threonine-protein kinase SMG1 isoform X3

      UniProtKB/TrEMBL
      F7ENF7
      Related
      ENSMMUP00000028725.3, ENSMMUT00000030691.4
      Conserved Domains (4) summary
      cd05170
      Location:2095 → 2428
      PIKKc_SMG1; Catalytic domain of Suppressor of Morphogenetic effect on Genitalia-1
      pfam02260
      Location:3633 → 3662
      FATC; FATC domain
      pfam15785
      Location:605 → 1216
      SMG1; Serine/threonine-protein kinase smg-1
      pfam17229
      Location:6 → 114
      DUF5303; Region of unknown function (DUF5303)

    5. XM_015125713.2 → XP_014981199.1  serine/threonine-protein kinase SMG1 isoform X3

      UniProtKB/TrEMBL
      F7ENF7
      Related
      ENSMMUP00000056613.2, ENSMMUT00000061354.2
      Conserved Domains (4) summary
      cd05170
      Location:2095 → 2428
      PIKKc_SMG1; Catalytic domain of Suppressor of Morphogenetic effect on Genitalia-1
      pfam02260
      Location:3633 → 3662
      FATC; FATC domain
      pfam15785
      Location:605 → 1216
      SMG1; Serine/threonine-protein kinase smg-1
      pfam17229
      Location:6 → 114
      DUF5303; Region of unknown function (DUF5303)
    Nucleotide Protein
    Heading Accession and Version

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