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    STING1 stimulator of interferon response cGAMP interactor 1 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 694353, updated on 17-Aug-2024

    Summary

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    Official Symbol
    STING1provided by VGNC
    Official Full Name
    stimulator of interferon response cGAMP interactor 1provided by VGNC
    Primary source
    VGNC:VGNC:79674
    See related
    Ensembl:ENSMMUG00000012048
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Also known as
    STING; TMEM173
    Orthologs
    human mouse all
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    Genomic context

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    See STING1 in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 6 NC_041759.1 (136885904..136893781, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 6 NC_027898.1 (137256393..137264264, complement)

    Chromosome 6 - NC_041759.1Genomic Context describing neighboring genes Neighboring gene endothelial cell surface expressed chemotaxis and apoptosis regulator Neighboring gene uncharacterized LOC693870 Neighboring gene small integral membrane protein 33 Neighboring gene cancer-related nucleoside-triphosphatase pseudogene Neighboring gene nuclear receptor coactivator 4-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Papain-Like Protease of Porcine Reproductive and Respiratory Syndrome Virus Impedes STING Translocation from the Endoplasmic Reticulum to the Golgi Apparatus by Deubiquitinating STIM1. Diao F, et al. J Virol, 2023 Apr 27. PMID 37039642, Free PMC Article
    2. STING controls nociception via type I interferon signalling in sensory neurons. Donnelly CR, et al. Nature, 2021 Mar. PMID 33442058, Free PMC Article
    3. Dengue viruses cleave STING in humans but not in nonhuman primates, their presumed natural reservoir. Stabell AC, et al. Elife, 2018 Mar 20. PMID 29557779, Free PMC Article
    4. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    5. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. STING controls nociception via type I interferon signalling in sensory neurons.
      Title: STING controls nociception via type I interferon signalling in sensory neurons.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables 2',3'-cyclic GMP-AMP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables cyclic-di-GMP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in activation of innate immune response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in autophagosome assembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in defense response to virus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in innate immune response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of macroautophagy IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of type I interferon production IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in reticulophagy IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in autophagosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    stimulator of interferon genes protein
    Names
    stimulator of interferon protein
    transmembrane protein 173

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041759.1 Reference Mmul_10 Primary Assembly

      Range
      136885904..136893781 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015141010.2 → XP_014996496.2  stimulator of interferon genes protein

      UniProtKB/TrEMBL
      F7HHU3, G7MUX1, H9YZQ6
      Related
      ENSMMUP00000015803.3, ENSMMUT00000016873.4
      Conserved Domains (1) summary
      pfam15009
      Location:44 → 337
      TMEM173; Transmembrane protein 173

    2. XM_028850089.1 → XP_028705922.1  stimulator of interferon genes protein

      UniProtKB/TrEMBL
      F7HHU3, G7MUX1, H9YZQ6
      Conserved Domains (1) summary
      pfam15009
      Location:44 → 337
      TMEM173; Transmembrane protein 173
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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