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    ARHGAP28 Rho GTPase activating protein 28 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 707240, updated on 17-Aug-2024

    Summary

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    Official Symbol
    ARHGAP28provided by VGNC
    Official Full Name
    Rho GTPase activating protein 28provided by VGNC
    Primary source
    VGNC:VGNC:69906
    See related
    Ensembl:ENSMMUG00000014506
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See ARHGAP28 in Genome Data Viewer
    Location:
    chromosome: 18
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 18 NC_041771.1 (67813826..68010138)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 18 NC_027910.1 (2664006..2860283, complement)

    Chromosome 18 - NC_041771.1Genomic Context describing neighboring genes Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC114673794 Neighboring gene 60S ribosomal protein L7-like 1 pseudogene Neighboring gene uncharacterized LOC106994419 Neighboring gene uncharacterized LOC106994418 Neighboring gene laminin subunit alpha 1 Neighboring gene solute carrier family 25 member 51-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables GTPase activator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of GTP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of stress fiber assembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of actin filament polymerization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of small GTPase mediated signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    rho GTPase-activating protein 28

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041771.1 Reference Mmul_10 Primary Assembly

      Range
      67813826..68010138
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028838212.1 → XP_028694045.1  rho GTPase-activating protein 28 isoform X1

      UniProtKB/TrEMBL
      F7AEK2
      Conserved Domains (1) summary
      cd04391
      Location:395 → 606
      RhoGAP_ARHGAP18; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of ArhGAP18-like proteins. The function of ArhGAP18 is unknown. Small GTPases cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but ...

    2. XM_028838214.1 → XP_028694047.1  rho GTPase-activating protein 28 isoform X3

      UniProtKB/TrEMBL
      F7AEK2
      Related
      ENSMMUP00000041319.3, ENSMMUT00000048285.3
      Conserved Domains (1) summary
      cd04391
      Location:365 → 576
      RhoGAP_ARHGAP18; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of ArhGAP18-like proteins. The function of ArhGAP18 is unknown. Small GTPases cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but ...

    3. XM_028838213.1 → XP_028694046.1  rho GTPase-activating protein 28 isoform X2

      UniProtKB/TrEMBL
      F7AEK2
      Conserved Domains (1) summary
      cd04391
      Location:390 → 601
      RhoGAP_ARHGAP18; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of ArhGAP18-like proteins. The function of ArhGAP18 is unknown. Small GTPases cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but ...

    4. XM_028838216.1 → XP_028694049.1  rho GTPase-activating protein 28 isoform X5

      UniProtKB/TrEMBL
      F7AEK2
      Conserved Domains (1) summary
      cd04391
      Location:325 → 536
      RhoGAP_ARHGAP18; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of ArhGAP18-like proteins. The function of ArhGAP18 is unknown. Small GTPases cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but ...

    5. XM_028838215.1 → XP_028694048.1  rho GTPase-activating protein 28 isoform X4

      UniProtKB/TrEMBL
      F7AEK2
      Conserved Domains (1) summary
      cd04391
      Location:342 → 553
      RhoGAP_ARHGAP18; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of ArhGAP18-like proteins. The function of ArhGAP18 is unknown. Small GTPases cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but ...

    6. XM_015121571.2 → XP_014977057.2  rho GTPase-activating protein 28 isoform X5

      UniProtKB/TrEMBL
      F7AEK2
      Conserved Domains (1) summary
      cd04391
      Location:325 → 536
      RhoGAP_ARHGAP18; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of ArhGAP18-like proteins. The function of ArhGAP18 is unknown. Small GTPases cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but ...

    7. XM_015121573.2 → XP_014977059.1  rho GTPase-activating protein 28 isoform X7

      UniProtKB/TrEMBL
      F7GEH6
      Related
      ENSMMUP00000019046.4, ENSMMUT00000020350.4
      Conserved Domains (1) summary
      cd04391
      Location:218 → 429
      RhoGAP_ARHGAP18; RhoGAP_ARHGAP18: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of ArhGAP18-like proteins. The function of ArhGAP18 is unknown. Small GTPases cluster into distinct families, and all act as molecular switches, active in their ...

    8. XM_015121572.2 → XP_014977058.1  rho GTPase-activating protein 28 isoform X6

      UniProtKB/TrEMBL
      F7AEK2
      Conserved Domains (1) summary
      cd04391
      Location:285 → 496
      RhoGAP_ARHGAP18; RhoGAP_ARHGAP18: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of ArhGAP18-like proteins. The function of ArhGAP18 is unknown. Small GTPases cluster into distinct families, and all act as molecular switches, active in their ...
    Nucleotide Protein
    Heading Accession and Version

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