NBR1 NBR1 autophagy cargo receptor [Macaca mulatta (Rhesus monkey)] - Gene

Summary

Official Symbol: NBR1provided by VGNC
Official Full Name: NBR1 autophagy cargo receptorprovided by VGNC
Primary source: VGNC:VGNC:75067
See related: Ensembl:ENSMMUG00000010433
Gene type: protein coding
RefSeq status: MODEL
Organism: Macaca mulatta
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 16

Exon count:: 24

Annotation release	Status	Assembly	Chr	Location
103	current	Mmul_10 (GCF_003339765.1)	16	NC_041769.1 (54286646..54328860)
102	previous assembly	Mmul_8.0.1 (GCF_000772875.2)	16	NC_027908.1 (49021859..49063752)

Chromosome 16 - NC_041769.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

GDB:439146 (e-PCR)
- UniSTS:157289

WI-21206 (e-PCR)
- UniSTS:47800

D17S1461E (e-PCR)
- UniSTS:150502

STS-U25764 (e-PCR)
- UniSTS:70137

RH70398 (e-PCR)
- UniSTS:82425

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables ubiquitin binding	IEA Inferred from Electronic Annotation more info	PubMed
enables zinc ion binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in macroautophagy	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in phagophore assembly site	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: next to BRCA1 gene 1 protein

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

NC_041769.1 Reference Mmul_10 Primary Assembly

Range

54286646..54328860

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_002800493.3 → XP_002800539.1 next to BRCA1 gene 1 protein isoform X1

See identical proteins and their annotated locations for XP_002800539.1

UniProtKB/TrEMBL

A0A5F7ZD70, H9FUE6, I0FRQ1

Related

ENSMMUP00000034380.3, ENSMMUT00000041352.3

Conserved Domains (4) summary

cd06396
Location:5 → 85

PB1_NBR1; The PB1 domain is an essential part of NBR1 protein, next to BRCA1, a scaffold protein mediating specific protein-protein interaction with both titin protein kinase and with another scaffold protein p62. A canonical PB1-PB1 interaction, which involves ...

cd02340
Location:216 → 260

ZZ_NBR1_like; Zinc finger, ZZ type. Zinc finger present in Drosophila ref(2)P, NBR1, Human sequestosome 1 and related proteins. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Drosophila ref(2)P appears ...

cd14319
Location:915 → 953

UBA_NBR1; UBA domain of next to BRCA1 gene 1 protein (NBR1) and similar proteins

cd14947
Location:370 → 480

NBR1_like; Functionally uncharacterized domain in neighbor of Brca1 Gene 1 and related proteins
XM_002800494.3 → XP_002800540.1 next to BRCA1 gene 1 protein isoform X1

See identical proteins and their annotated locations for XP_002800540.1

UniProtKB/TrEMBL

A0A5F7ZD70, H9FUE6, I0FRQ1

Conserved Domains (4) summary

cd06396
Location:5 → 85

PB1_NBR1; The PB1 domain is an essential part of NBR1 protein, next to BRCA1, a scaffold protein mediating specific protein-protein interaction with both titin protein kinase and with another scaffold protein p62. A canonical PB1-PB1 interaction, which involves ...

cd02340
Location:216 → 260

ZZ_NBR1_like; Zinc finger, ZZ type. Zinc finger present in Drosophila ref(2)P, NBR1, Human sequestosome 1 and related proteins. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Drosophila ref(2)P appears ...

cd14319
Location:915 → 953

UBA_NBR1; UBA domain of next to BRCA1 gene 1 protein (NBR1) and similar proteins

cd14947
Location:370 → 480

NBR1_like; Functionally uncharacterized domain in neighbor of Brca1 Gene 1 and related proteins
XM_001097043.2 → XP_001097043.2 next to BRCA1 gene 1 protein isoform X1

See identical proteins and their annotated locations for XP_001097043.2

UniProtKB/TrEMBL

A0A5F7ZD70, H9FUE6, I0FRQ1

Related

ENSMMUP00000062584.1, ENSMMUT00000088599.1

Conserved Domains (4) summary

cd06396
Location:5 → 85

PB1_NBR1; The PB1 domain is an essential part of NBR1 protein, next to BRCA1, a scaffold protein mediating specific protein-protein interaction with both titin protein kinase and with another scaffold protein p62. A canonical PB1-PB1 interaction, which involves ...

cd02340
Location:216 → 260

ZZ_NBR1_like; Zinc finger, ZZ type. Zinc finger present in Drosophila ref(2)P, NBR1, Human sequestosome 1 and related proteins. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Drosophila ref(2)P appears ...

cd14319
Location:915 → 953

UBA_NBR1; UBA domain of next to BRCA1 gene 1 protein (NBR1) and similar proteins

cd14947
Location:370 → 480

NBR1_like; Functionally uncharacterized domain in neighbor of Brca1 Gene 1 and related proteins
XM_028836534.1 → XP_028692367.1 next to BRCA1 gene 1 protein isoform X2

UniProtKB/TrEMBL

H9FUE6, I0FRQ1

Conserved Domains (4) summary

cd06396
Location:5 → 85

PB1_NBR1; The PB1 domain is an essential part of NBR1 protein, next to BRCA1, a scaffold protein mediating specific protein-protein interaction with both titin protein kinase and with another scaffold protein p62. A canonical PB1-PB1 interaction, which involves ...

cd02340
Location:216 → 260

ZZ_NBR1_like; Zinc finger, ZZ type. Zinc finger present in Drosophila ref(2)P, NBR1, Human sequestosome 1 and related proteins. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Drosophila ref(2)P appears ...

cd14319
Location:860 → 898

UBA_NBR1; UBA domain of next to BRCA1 gene 1 protein (NBR1) and similar proteins

cd14947
Location:370 → 480

NBR1_like; Functionally uncharacterized domain in neighbor of Brca1 Gene 1 and related proteins
XM_028836536.1 → XP_028692369.1 next to BRCA1 gene 1 protein isoform X6

UniProtKB/TrEMBL

H9FUE6, I0FRQ1

Conserved Domains (4) summary

cd06396
Location:5 → 85

PB1_NBR1; The PB1 domain is an essential part of NBR1 protein, next to BRCA1, a scaffold protein mediating specific protein-protein interaction with both titin protein kinase and with another scaffold protein p62. A canonical PB1-PB1 interaction, which involves ...

cd02340
Location:216 → 260

ZZ_NBR1_like; Zinc finger, ZZ type. Zinc finger present in Drosophila ref(2)P, NBR1, Human sequestosome 1 and related proteins. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Drosophila ref(2)P appears ...

cd14319
Location:823 → 861

UBA_NBR1; UBA domain of next to BRCA1 gene 1 protein (NBR1) and similar proteins

cd14947
Location:370 → 480

NBR1_like; Functionally uncharacterized domain in neighbor of Brca1 Gene 1 and related proteins
XM_015119810.1 → XP_014975296.1 next to BRCA1 gene 1 protein isoform X5

UniProtKB/TrEMBL

H9FUE6, I0FRQ1

Conserved Domains (4) summary

cd06396
Location:5 → 85

PB1_NBR1; The PB1 domain is an essential part of NBR1 protein, next to BRCA1, a scaffold protein mediating specific protein-protein interaction with both titin protein kinase and with another scaffold protein p62. A canonical PB1-PB1 interaction, which involves ...

cd02340
Location:216 → 260

ZZ_NBR1_like; Zinc finger, ZZ type. Zinc finger present in Drosophila ref(2)P, NBR1, Human sequestosome 1 and related proteins. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Drosophila ref(2)P appears ...

cd14319
Location:845 → 883

UBA_NBR1; UBA domain of next to BRCA1 gene 1 protein (NBR1) and similar proteins

cd14947
Location:300 → 410

NBR1_like; Functionally uncharacterized domain in neighbor of Brca1 Gene 1 and related proteins
XM_028836535.1 → XP_028692368.1 next to BRCA1 gene 1 protein isoform X3

UniProtKB/TrEMBL

F7CX01, H9FUE6, I0FRQ1

Related

ENSMMUP00000013677.4, ENSMMUT00000014599.4

Conserved Domains (5) summary

cd06396
Location:5 → 85

PB1_NBR1; The PB1 domain is an essential part of NBR1 protein, next to BRCA1, a scaffold protein mediating specific protein-protein interaction with both titin protein kinase and with another scaffold protein p62. A canonical PB1-PB1 interaction, which involves ...

cd14319
Location:859 → 897

UBA_NBR1; UBA domain of next to BRCA1 gene 1 protein (NBR1) and similar proteins

cd14947
Location:314 → 424

NBR1_like; Functionally uncharacterized domain in neighbor of Brca1 Gene 1 and related proteins

cl00295
Location:216 → 232

ZZ; Zinc finger, ZZ type. Zinc finger present in dystrophin, CBP/p300 and many other proteins. The ZZ motif coordinates one or two zinc ions and most likely participates in ligand binding or molecular scaffolding. Many proteins containing ZZ motifs have ...

cl21462
Location:216 → 269

bZIP; Basic leucine zipper (bZIP) domain of bZIP transcription factors: a DNA-binding and dimerization domain
XM_015119809.1 → XP_014975295.1 next to BRCA1 gene 1 protein isoform X4

UniProtKB/TrEMBL

A0A5F8ACS9, H9FUE6, I0FRQ1

Related

ENSMMUP00000075743.1, ENSMMUT00000102076.1

Conserved Domains (5) summary

cd02340
Location:150 → 194

ZZ_NBR1_like; Zinc finger, ZZ type. Zinc finger present in Drosophila ref(2)P, NBR1, Human sequestosome 1 and related proteins. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Drosophila ref(2)P appears ...

cd14319
Location:849 → 887

UBA_NBR1; UBA domain of next to BRCA1 gene 1 protein (NBR1) and similar proteins

cd14947
Location:304 → 414

NBR1_like; Functionally uncharacterized domain in neighbor of Brca1 Gene 1 and related proteins

pfam10883
Location:223 → 259

DUF2681; Protein of unknown function (DUF2681)

cl02720
Location:5 → 70

PB1; The PB1 domain is a modular domain mediating specific protein-protein interactions which play a role in many critical cell processes, such as osteoclastogenesis, angiogenesis, early cardiovascular development, and cell polarity. A canonical PB1-PB1 ...
XM_015119811.2 → XP_014975297.1 next to BRCA1 gene 1 protein isoform X8

UniProtKB/TrEMBL

H9FUE6, I0FRQ1

Conserved Domains (4) summary

cd06396
Location:5 → 85

PB1_NBR1; The PB1 domain is an essential part of NBR1 protein, next to BRCA1, a scaffold protein mediating specific protein-protein interaction with both titin protein kinase and with another scaffold protein p62. A canonical PB1-PB1 interaction, which involves ...

cd02340
Location:216 → 260

ZZ_NBR1_like; Zinc finger, ZZ type. Zinc finger present in Drosophila ref(2)P, NBR1, Human sequestosome 1 and related proteins. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Drosophila ref(2)P appears ...

cd14947
Location:370 → 480

NBR1_like; Functionally uncharacterized domain in neighbor of Brca1 Gene 1 and related proteins

pfam10883
Location:289 → 325

DUF2681; Protein of unknown function (DUF2681)
XM_028836537.1 → XP_028692370.1 next to BRCA1 gene 1 protein isoform X7

UniProtKB/TrEMBL

A0A1D5QG63, A0A1D5R6R5, F6PK87

Conserved Domains (3) summary

cd14319
Location:733 → 771

UBA_NBR1; UBA domain of next to BRCA1 gene 1 protein (NBR1) and similar proteins

cd14947
Location:188 → 298

NBR1_like; Functionally uncharacterized domain in neighbor of Brca1 Gene 1 and related proteins

cl00295
Location:51 → 78

ZZ; Zinc finger, ZZ type. Zinc finger present in dystrophin, CBP/p300 and many other proteins. The ZZ motif coordinates one or two zinc ions and most likely participates in ligand binding or molecular scaffolding. Many proteins containing ZZ motifs have ...