ADRB3 adrenoceptor beta 3 [Macaca mulatta (Rhesus monkey)] - Gene

Summary

Official Symbol: ADRB3provided by VGNC
Official Full Name: adrenoceptor beta 3provided by VGNC
Primary source: VGNC:VGNC:83978
See related: Ensembl:ENSMMUG00000005876
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Macaca mulatta
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 8

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
103	current	Mmul_10 (GCF_003339765.1)	8	NC_041761.1 (38430421..38432708, complement)
102	previous assembly	Mmul_8.0.1 (GCF_000772875.2)	8	NC_027900.1 (38239145..38241437, complement)

Chromosome 8 - NC_041761.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Up-regulation of cardiac beta3-adrenoreceptor signaling enhances inhibition of left ventricular myocyte contraction and relaxation, exacerbates the dysfunctional calcium channels and may precede the development of alcoholic cardiomyopathy.
Title: Up-regulation and functional effect of cardiac β3-adrenoreceptors in alcoholic monkeys.

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General gene information

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Markers

ADRB3 (e-PCR)
- UniSTS:506234

PMC164531P1 (e-PCR)
- UniSTS:271495

MARC_68773-68774:1209743884:2 (e-PCR)
- UniSTS:528345

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables beta3-adrenergic receptor activity	IEA Inferred from Electronic Annotation more info	PubMed
enables epinephrine binding	IEA Inferred from Electronic Annotation more info	PubMed
enables norepinephrine binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in adenylate cyclase-activating adrenergic receptor signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: beta-3 adrenergic receptor

Names: adrenergic, beta-3-, receptor; beta-3 adrenoceptor; beta-3 adrenoreceptor

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.