IFNB1 interferon beta 1 [Macaca mulatta (Rhesus monkey)] - Gene

Summary

Official Symbol: IFNB1provided by VGNC
Official Full Name: interferon beta 1provided by VGNC
Primary source: VGNC:VGNC:73567
See related: Ensembl:ENSMMUG00000019067
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Macaca mulatta
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 15

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
103	current	Mmul_10 (GCF_003339765.1)	15	NC_041768.1 (62578511..62579074)
102	previous assembly	Mmul_8.0.1 (GCF_000772875.2)	15	NC_027907.1 (62862968..62863531)

Chromosome 15 - NC_041768.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

either JC1 or DS1 C/EBP site is sufficient to mediate IFN beta-induced down-regulation of SIV long terminal repeat activity and virus replication in macrophages
Title: Regulation of SIV mac 239 basal long terminal repeat activity and viral replication in macrophages: functional roles of two CCAAT/enhancer-binding protein beta sites in activation and interferon beta-mediated suppression.
Hepatitis A virus protein 2B suppresses beta interferon (IFN) gene transcription by interfering with IFN regulatory factor 3 activation.
Title: Hepatitis A virus protein 2B suppresses beta interferon (IFN) gene transcription by interfering with IFN regulatory factor 3 activation.

Submit: New GeneRIF Correction

General gene information

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Markers

PMC129788P3 (e-PCR)
- UniSTS:270604

PMC13914P2 (e-PCR)
- UniSTS:270876

PMC204479P2 (e-PCR)
- UniSTS:271941

NoName (e-PCR)
- UniSTS:481607

IFNB1_144 (e-PCR)
- UniSTS:277353

PMC153761P1 (e-PCR)
- UniSTS:271268

D9S2016 (e-PCR)
- UniSTS:45758

PMC136892P1 (e-PCR)
- UniSTS:270807

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables cytokine activity	IEA Inferred from Electronic Annotation more info	PubMed
enables type I interferon receptor binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in B cell differentiation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in B cell proliferation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in T cell activation involved in immune response	IEA Inferred from Electronic Annotation more info	PubMed
involved_in adaptive immune response	IEA Inferred from Electronic Annotation more info	PubMed
involved_in cytokine-mediated signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in defense response	IEA Inferred from Electronic Annotation more info	PubMed
involved_in humoral immune response	IEA Inferred from Electronic Annotation more info	PubMed
involved_in natural killer cell activation involved in immune response	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of peptidyl-serine phosphorylation of STAT protein	IEA Inferred from Electronic Annotation more info	PubMed
involved_in response to exogenous dsRNA	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in extracellular region	IEA Inferred from Electronic Annotation more info	PubMed
located_in extracellular space	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: interferon beta

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.