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    HTR2B 5-hydroxytryptamine receptor 2B [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 711808, updated on 17-Aug-2024

    Summary

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    Official Symbol
    HTR2Bprovided by VGNC
    Official Full Name
    5-hydroxytryptamine receptor 2Bprovided by VGNC
    Primary source
    VGNC:VGNC:73540
    See related
    Ensembl:ENSMMUG00000011773
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See HTR2B in Genome Data Viewer
    Location:
    chromosome: 12
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 12 NC_041765.1 (118531938..118551028, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 12 NC_027904.1 (113545794..113564177, complement)

    Chromosome 12 - NC_041765.1Genomic Context describing neighboring genes Neighboring gene spermatogenesis associated 3 Neighboring gene chromosome 12 C2orf72 homolog Neighboring gene proteasome 26S subunit, non-ATPase 1 Neighboring gene U1 spliceosomal RNA Neighboring gene armadillo repeat containing 9

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables G protein-coupled serotonin receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables neurotransmitter receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in chemical synaptic transmission IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in heart development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of behavior IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in smooth muscle contraction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in vasoconstriction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in dendrite IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    5-hydroxytryptamine receptor 2B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041765.1 Reference Mmul_10 Primary Assembly

      Range
      118531938..118551028 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028831206.1 → XP_028687039.1  5-hydroxytryptamine receptor 2B isoform X2

      UniProtKB/TrEMBL
      G7N950
      Conserved Domains (2) summary
      cd14964
      Location:57 → 81
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:55 → 331
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    2. XM_028831205.1 → XP_028687038.1  5-hydroxytryptamine receptor 2B isoform X1

      UniProtKB/TrEMBL
      F7HQF4, G7N950
      Conserved Domains (1) summary
      cd15306
      Location:55 → 398
      7tmA_5-HT2B; serotonin receptor subtype 2B, member of the class A family of seven-transmembrane G protein-coupled receptors

    3. XM_015111331.2 → XP_014966817.1  5-hydroxytryptamine receptor 2B isoform X1

      UniProtKB/TrEMBL
      F7HQF4, G7N950
      Related
      ENSMMUP00000015461.2, ENSMMUT00000016502.4
      Conserved Domains (1) summary
      cd15306
      Location:55 → 398
      7tmA_5-HT2B; serotonin receptor subtype 2B, member of the class A family of seven-transmembrane G protein-coupled receptors
    Nucleotide Protein
    Heading Accession and Version

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