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    TYMS thymidylate synthetase [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 697580, updated on 17-Aug-2024

    Summary

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    Official Symbol
    TYMSprovided by VGNC
    Official Full Name
    thymidylate synthetaseprovided by VGNC
    Primary source
    VGNC:VGNC:78681
    See related
    Ensembl:ENSMMUG00000004046
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See TYMS in Genome Data Viewer
    Location:
    chromosome: 18
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 18 NC_041771.1 (61963940..61976091)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 18 NC_027910.1 (8836531..8848732, complement)

    Chromosome 18 - NC_041771.1Genomic Context describing neighboring genes Neighboring gene clusterin like 1 Neighboring gene uncharacterized LOC106994432 Neighboring gene enolase superfamily member 1 Neighboring gene YES proto-oncogene 1, Src family tyrosine kinase Neighboring gene U1 spliceosomal RNA

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Evolution of metamorphism in thymidylate synthases within the primate lineages. Luo B, et al. J Mol Evol, 2011 Mar. PMID 21318388
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables thymidylate synthase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in dTMP biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    thymidylate synthase
    NP_001182436.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001195507.1 → NP_001182436.1  thymidylate synthase

      Status: PROVISIONAL

      Source sequence(s)
      FS722573, FS723511
      Related
      ENSMMUP00000005405.3, ENSMMUT00000005741.4
      Conserved Domains (1) summary
      pfam00303
      Location:32 → 313
      Thymidylat_synt; Thymidylate synthase

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041771.1 Reference Mmul_10 Primary Assembly

      Range
      61963940..61976091
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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