U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    GDNF glial cell derived neurotrophic factor [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 706345, updated on 17-Aug-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    GDNFprovided by VGNC
    Official Full Name
    glial cell derived neurotrophic factorprovided by VGNC
    Primary source
    VGNC:VGNC:72912
    See related
    Ensembl:ENSMMUG00000018963
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See GDNF in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 6 NC_041759.1 (37664534..37692642, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 6 NC_027898.1 (38331646..38359148, complement)

    Chromosome 6 - NC_041759.1Genomic Context describing neighboring genes Neighboring gene WD repeat domain 70 Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC114678678 Neighboring gene uncharacterized LOC106998719 Neighboring gene uncharacterized LOC106998721 Neighboring gene uncharacterized LOC106998722

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Response of aged parkinsonian monkeys to in vivo gene transfer of GDNF. Emborg ME, et al. Neurobiol Dis, 2009 Nov. PMID 19660547, Free PMC Article
    2. Increased expression of B-lymphocyte chemoattractant, but not pro-inflammatory cytokines, in muscle tissue in rhesus chronic Lyme borreliosis. Pachner AR, et al. Cytokine, 2002 Sep 21. PMID 12421572
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables glial cell-derived neurotrophic factor receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables growth factor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables receptor tyrosine kinase binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of neuron apoptotic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in peripheral nervous system development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of branching involved in ureteric bud morphogenesis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    glial cell line-derived neurotrophic factor
    Names
    glial cell line derived neurotrophic factor
    neurotrophic factor

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041759.1 Reference Mmul_10 Primary Assembly

      Range
      37664534..37692642 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001094714.4 → XP_001094714.2  glial cell line-derived neurotrophic factor isoform X1

      See identical proteins and their annotated locations for XP_001094714.2

      UniProtKB/TrEMBL
      A0A1D5R2Z3
      Related
      ENSMMUP00000054678.2, ENSMMUT00000067323.2
      Conserved Domains (1) summary
      pfam00019
      Location:116 → 210
      TGF_beta; Transforming growth factor beta like domain

    2. XM_015139905.2 → XP_014995391.1  glial cell line-derived neurotrophic factor isoform X2

      UniProtKB/TrEMBL
      G7MPR1
      Conserved Domains (1) summary
      cd19380
      Location:89 → 184
      TGF_beta_GDNF; transforming growth factor beta (TGF-beta) like domain found in glial cell line-derived neurotrophic factor (GDNF) and similar proteins
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.