U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 696973, updated on 17-Aug-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    SMARCA2provided by VGNC
    Official Full Name
    SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2provided by VGNC
    Primary source
    VGNC:VGNC:77647
    See related
    Ensembl:ENSMMUG00000015279
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Also known as
    brm
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See SMARCA2 in Genome Data Viewer
    Location:
    chromosome: 15
    Exon count:
    41
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 15 NC_041768.1 (81686163..81868567, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 15 NC_027907.1 (82339129..82563621, complement)

    Chromosome 15 - NC_041768.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106993776 Neighboring gene bcl-2-like protein 12 pseudogene Neighboring gene very low density lipoprotein receptor Neighboring gene uncharacterized LOC114672805 Neighboring gene uncharacterized LOC106993778 Neighboring gene U2 spliceosomal RNA Neighboring gene doublesex and mab-3 related transcription factor 2 Neighboring gene doublesex and mab-3 related transcription factor 3

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ATP-dependent chromatin remodeler activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables histone binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in chromatin remodeling IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of RSC-type complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    probable global transcription activator SNF2L2
    Names
    putative global transcription activator SNF2L2

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041768.1 Reference Mmul_10 Primary Assembly

      Range
      81686163..81868567 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028835200.1 → XP_028691033.1  probable global transcription activator SNF2L2 isoform X1

      UniProtKB/TrEMBL
      F7DUE0
      Conserved Domains (9) summary
      cd05516
      Location:1378 → 1502
      Bromo_SNF2L2; Bromodomain, SNF2L2-like subfamily, specific to animals. SNF2L2 (SNF2-alpha) or SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 is a global transcriptional activator, which cooperates with nuclear hormone ...
      smart00573
      Location:432 → 504
      HSA; domain in helicases and associated with SANT domains
      PLN03142
      Location:716 → 1198
      PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
      PHA03378
      Location:66 → 378
      PHA03378; EBNA-3B; Provisional
      cd18063
      Location:697 → 947
      DEXHc_SMARCA2; DEXH-box helicase domain of SMARCA2
      pfam07533
      Location:586 → 628
      BRK; BRK domain
      pfam08880
      Location:173 → 207
      QLQ
      pfam14619
      Location:1256 → 1322
      SnAC; Snf2-ATP coupling, chromatin remodelling complex
      cl02556
      Location:1329 → 1415
      Bromodomain; Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.

    2. XM_028835201.1 → XP_028691034.1  probable global transcription activator SNF2L2 isoform X2

      UniProtKB/TrEMBL
      A0A1D5Q2T8
      Related
      ENSMMUP00000042350.2, ENSMMUT00000071563.2
      Conserved Domains (9) summary
      cd05516
      Location:1378 → 1484
      Bromo_SNF2L2; Bromodomain, SNF2L2-like subfamily, specific to animals. SNF2L2 (SNF2-alpha) or SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 is a global transcriptional activator, which cooperates with nuclear hormone ...
      smart00573
      Location:432 → 504
      HSA; domain in helicases and associated with SANT domains
      PLN03142
      Location:716 → 1198
      PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
      PHA03378
      Location:66 → 378
      PHA03378; EBNA-3B; Provisional
      cd18063
      Location:697 → 947
      DEXHc_SMARCA2; DEXH-box helicase domain of SMARCA2
      pfam07533
      Location:586 → 628
      BRK; BRK domain
      pfam08880
      Location:173 → 207
      QLQ
      pfam14619
      Location:1256 → 1322
      SnAC; Snf2-ATP coupling, chromatin remodelling complex
      cl02556
      Location:1329 → 1391
      Bromodomain; Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.

    3. XM_028835202.1 → XP_028691035.1  probable global transcription activator SNF2L2 isoform X3

      Conserved Domains (9) summary
      cd05516
      Location:1378 → 1502
      Bromo_SNF2L2; Bromodomain, SNF2L2-like subfamily, specific to animals. SNF2L2 (SNF2-alpha) or SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 is a global transcriptional activator, which cooperates with nuclear hormone ...
      smart00573
      Location:432 → 504
      HSA; domain in helicases and associated with SANT domains
      PLN03142
      Location:716 → 1198
      PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
      PHA03378
      Location:66 → 378
      PHA03378; EBNA-3B; Provisional
      cd18063
      Location:697 → 947
      DEXHc_SMARCA2; DEXH-box helicase domain of SMARCA2
      pfam07533
      Location:586 → 628
      BRK; BRK domain
      pfam08880
      Location:173 → 207
      QLQ
      pfam14619
      Location:1256 → 1322
      SnAC; Snf2-ATP coupling, chromatin remodelling complex
      cl02556
      Location:1329 → 1415
      Bromodomain; Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.

    4. XM_015117813.2 → XP_014973299.1  probable global transcription activator SNF2L2 isoform X1

      UniProtKB/TrEMBL
      F7DUE0
      Conserved Domains (9) summary
      cd05516
      Location:1378 → 1502
      Bromo_SNF2L2; Bromodomain, SNF2L2-like subfamily, specific to animals. SNF2L2 (SNF2-alpha) or SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 is a global transcriptional activator, which cooperates with nuclear hormone ...
      smart00573
      Location:432 → 504
      HSA; domain in helicases and associated with SANT domains
      PLN03142
      Location:716 → 1198
      PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
      PHA03378
      Location:66 → 378
      PHA03378; EBNA-3B; Provisional
      cd18063
      Location:697 → 947
      DEXHc_SMARCA2; DEXH-box helicase domain of SMARCA2
      pfam07533
      Location:586 → 628
      BRK; BRK domain
      pfam08880
      Location:173 → 207
      QLQ
      pfam14619
      Location:1256 → 1322
      SnAC; Snf2-ATP coupling, chromatin remodelling complex
      cl02556
      Location:1329 → 1415
      Bromodomain; Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.

    5. XM_015117811.2 → XP_014973297.1  probable global transcription activator SNF2L2 isoform X1

      UniProtKB/TrEMBL
      F7DUE0
      Conserved Domains (9) summary
      cd05516
      Location:1378 → 1502
      Bromo_SNF2L2; Bromodomain, SNF2L2-like subfamily, specific to animals. SNF2L2 (SNF2-alpha) or SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 is a global transcriptional activator, which cooperates with nuclear hormone ...
      smart00573
      Location:432 → 504
      HSA; domain in helicases and associated with SANT domains
      PLN03142
      Location:716 → 1198
      PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
      PHA03378
      Location:66 → 378
      PHA03378; EBNA-3B; Provisional
      cd18063
      Location:697 → 947
      DEXHc_SMARCA2; DEXH-box helicase domain of SMARCA2
      pfam07533
      Location:586 → 628
      BRK; BRK domain
      pfam08880
      Location:173 → 207
      QLQ
      pfam14619
      Location:1256 → 1322
      SnAC; Snf2-ATP coupling, chromatin remodelling complex
      cl02556
      Location:1329 → 1415
      Bromodomain; Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.

    6. XM_015117810.2 → XP_014973296.1  probable global transcription activator SNF2L2 isoform X1

      UniProtKB/TrEMBL
      F7DUE0
      Related
      ENSMMUP00000020039.3, ENSMMUT00000021425.4
      Conserved Domains (9) summary
      cd05516
      Location:1378 → 1502
      Bromo_SNF2L2; Bromodomain, SNF2L2-like subfamily, specific to animals. SNF2L2 (SNF2-alpha) or SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 is a global transcriptional activator, which cooperates with nuclear hormone ...
      smart00573
      Location:432 → 504
      HSA; domain in helicases and associated with SANT domains
      PLN03142
      Location:716 → 1198
      PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
      PHA03378
      Location:66 → 378
      PHA03378; EBNA-3B; Provisional
      cd18063
      Location:697 → 947
      DEXHc_SMARCA2; DEXH-box helicase domain of SMARCA2
      pfam07533
      Location:586 → 628
      BRK; BRK domain
      pfam08880
      Location:173 → 207
      QLQ
      pfam14619
      Location:1256 → 1322
      SnAC; Snf2-ATP coupling, chromatin remodelling complex
      cl02556
      Location:1329 → 1415
      Bromodomain; Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.

    7. XM_015117818.2 → XP_014973304.1  probable global transcription activator SNF2L2 isoform X5

      UniProtKB/TrEMBL
      H9FBW5
      Conserved Domains (11) summary
      cd05516
      Location:1285 → 1409
      Bromo_SNF2L2; Bromodomain, SNF2L2-like subfamily, specific to animals. SNF2L2 (SNF2-alpha) or SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 is a global transcriptional activator, which cooperates with nuclear hormone ...
      smart00592
      Location:493 → 535
      BRK; domain in transcription and CHROMO domain helicases
      smart00573
      Location:339 → 411
      HSA; domain in helicases and associated with SANT domains
      cd00046
      Location:647 → 786
      DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
      pfam00176
      Location:630 → 925
      SNF2_N; SNF2 family N-terminal domain
      pfam00271
      Location:952 → 1067
      Helicase_C; Helicase conserved C-terminal domain
      pfam08880
      Location:80 → 114
      QLQ; QLQ
      pfam12067
      Location:5 → 106
      Sox_C_TAD; Sox C-terminal transactivation domain
      pfam14619
      Location:1162 → 1229
      SnAC; Snf2-ATP coupling, chromatin remodelling complex
      pfam15240
      Location:5 → 88
      Pro-rich; Proline-rich
      cl02556
      Location:1236 → 1322
      Bromodomain; Bromodomain. Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.

    8. XM_015117817.2 → XP_014973303.1  probable global transcription activator SNF2L2 isoform X5

      UniProtKB/TrEMBL
      H9FBW5
      Conserved Domains (11) summary
      cd05516
      Location:1285 → 1409
      Bromo_SNF2L2; Bromodomain, SNF2L2-like subfamily, specific to animals. SNF2L2 (SNF2-alpha) or SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 is a global transcriptional activator, which cooperates with nuclear hormone ...
      smart00592
      Location:493 → 535
      BRK; domain in transcription and CHROMO domain helicases
      smart00573
      Location:339 → 411
      HSA; domain in helicases and associated with SANT domains
      cd00046
      Location:647 → 786
      DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
      pfam00176
      Location:630 → 925
      SNF2_N; SNF2 family N-terminal domain
      pfam00271
      Location:952 → 1067
      Helicase_C; Helicase conserved C-terminal domain
      pfam08880
      Location:80 → 114
      QLQ; QLQ
      pfam12067
      Location:5 → 106
      Sox_C_TAD; Sox C-terminal transactivation domain
      pfam14619
      Location:1162 → 1229
      SnAC; Snf2-ATP coupling, chromatin remodelling complex
      pfam15240
      Location:5 → 88
      Pro-rich; Proline-rich
      cl02556
      Location:1236 → 1322
      Bromodomain; Bromodomain. Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.

    9. XM_028835204.1 → XP_028691037.1  probable global transcription activator SNF2L2 isoform X7

      Conserved Domains (2) summary
      cd05516
      Location:58 → 164
      Bromo_SNF2L2; Bromodomain, SNF2L2-like subfamily, specific to animals. SNF2L2 (SNF2-alpha) or SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 is a global transcriptional activator, which cooperates with nuclear hormone ...
      cl02556
      Location:9 → 71
      Bromodomain; Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.

    10. XM_015117821.2 → XP_014973307.1  probable global transcription activator SNF2L2 isoform X6

      UniProtKB/TrEMBL
      F7DU54
      Conserved Domains (2) summary
      cd05516
      Location:86 → 192
      Bromo_SNF2L2; Bromodomain, SNF2L2-like subfamily, specific to animals. SNF2L2 (SNF2-alpha) or SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 is a global transcriptional activator, which cooperates with nuclear hormone ...
      cl02556
      Location:37 → 99
      Bromodomain; Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.

    11. XM_015117819.2 → XP_014973305.1  probable global transcription activator SNF2L2 isoform X6

      UniProtKB/TrEMBL
      F7DU54
      Related
      ENSMMUP00000039162.3, ENSMMUT00000046118.3
      Conserved Domains (2) summary
      cd05516
      Location:86 → 192
      Bromo_SNF2L2; Bromodomain, SNF2L2-like subfamily, specific to animals. SNF2L2 (SNF2-alpha) or SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 is a global transcriptional activator, which cooperates with nuclear hormone ...
      cl02556
      Location:37 → 99
      Bromodomain; Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.

    12. XM_015117820.2 → XP_014973306.1  probable global transcription activator SNF2L2 isoform X6

      UniProtKB/TrEMBL
      F7DU54
      Related
      ENSMMUP00000020041.3, ENSMMUT00000021427.4
      Conserved Domains (2) summary
      cd05516
      Location:86 → 192
      Bromo_SNF2L2; Bromodomain, SNF2L2-like subfamily, specific to animals. SNF2L2 (SNF2-alpha) or SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 is a global transcriptional activator, which cooperates with nuclear hormone ...
      cl02556
      Location:37 → 99
      Bromodomain; Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.

    13. XM_028835203.1 → XP_028691036.1  probable global transcription activator SNF2L2 isoform X4

      Conserved Domains (9) summary
      cd05516
      Location:1378 → 1484
      Bromo_SNF2L2; Bromodomain, SNF2L2-like subfamily, specific to animals. SNF2L2 (SNF2-alpha) or SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 is a global transcriptional activator, which cooperates with nuclear hormone ...
      smart00573
      Location:432 → 504
      HSA; domain in helicases and associated with SANT domains
      PLN03142
      Location:716 → 1198
      PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
      pfam03154
      Location:46 → 446
      Atrophin-1; Atrophin-1 family
      pfam07533
      Location:586 → 626
      BRK; BRK domain
      pfam08880
      Location:173 → 207
      QLQ
      pfam14619
      Location:1255 → 1322
      SnAC; Snf2-ATP coupling, chromatin remodelling complex
      cd18063
      Location:697 → 947
      DEXHc_SMARCA2; DEXH-box helicase domain of SMARCA2
      cl02556
      Location:1329 → 1391
      Bromodomain; Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.