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    CRADD CASP2 and RIPK1 domain containing adaptor with death domain [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 711165, updated on 17-Aug-2024

    Summary

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    Official Symbol
    CRADDprovided by VGNC
    Official Full Name
    CASP2 and RIPK1 domain containing adaptor with death domainprovided by VGNC
    Primary source
    VGNC:VGNC:71482
    Locus tag
    EGK_04059
    See related
    Ensembl:ENSMMUG00000012670
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See CRADD in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 11 NC_041764.1 (93469301..93648566)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 11 NC_027903.1 (93419215..93643157)

    Chromosome 11 - NC_041764.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC114670918 Neighboring gene suppressor of cytokine signaling 2 Neighboring gene uncharacterized LOC107000974 Neighboring gene uncharacterized LOC114670919

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables death domain binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protease binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of apoptotic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    death domain-containing protein CRADD
    Names
    Caspase and RIP adapter

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001267004.1 → NP_001253933.1  death domain-containing protein CRADD

      See identical proteins and their annotated locations for NP_001253933.1

      Status: PROVISIONAL

      Source sequence(s)
      JU477647
      UniProtKB/TrEMBL
      A0A1D5QRW9, A0A8J8YQU4, G7N7Z0, I0FHQ0
      Related
      ENSMMUP00000050797.1, ENSMMUT00000053973.2
      Conserved Domains (2) summary
      cd08319
      Location:116 → 198
      Death_RAIDD; Death domain of RIP-associated ICH-1 homologous protein with a death domain
      cd08327
      Location:1 → 94
      CARD_RAIDD; Caspase activation and recruitment domain of RIP-associated ICH-1 homologous protein with a death domain

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041764.1 Reference Mmul_10 Primary Assembly

      Range
      93469301..93648566
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028828940.1 → XP_028684773.1  death domain-containing protein CRADD isoform X4

      Conserved Domains (1) summary
      cd08327
      Location:1 → 94
      CARD_RAIDD; Caspase activation and recruitment domain of RIP-associated ICH-1 homologous protein with a death domain

    2. XM_028828943.1 → XP_028684776.1  death domain-containing protein CRADD isoform X7

      Conserved Domains (1) summary
      cd08327
      Location:1 → 94
      CARD_RAIDD; Caspase activation and recruitment domain of RIP-associated ICH-1 homologous protein with a death domain

    3. XM_028828937.1 → XP_028684770.1  death domain-containing protein CRADD isoform X1

      Conserved Domains (1) summary
      cd08327
      Location:1 → 94
      CARD_RAIDD; Caspase activation and recruitment domain of RIP-associated ICH-1 homologous protein with a death domain

    4. XM_028828939.1 → XP_028684772.1  death domain-containing protein CRADD isoform X3

      Conserved Domains (1) summary
      cd08327
      Location:1 → 94
      CARD_RAIDD; Caspase activation and recruitment domain of RIP-associated ICH-1 homologous protein with a death domain

    5. XM_028828941.1 → XP_028684774.1  death domain-containing protein CRADD isoform X5

      Conserved Domains (1) summary
      cd08327
      Location:1 → 94
      CARD_RAIDD; Caspase activation and recruitment domain of RIP-associated ICH-1 homologous protein with a death domain

    6. XM_028828942.1 → XP_028684775.1  death domain-containing protein CRADD isoform X6

      Conserved Domains (1) summary
      cd08327
      Location:1 → 94
      CARD_RAIDD; Caspase activation and recruitment domain of RIP-associated ICH-1 homologous protein with a death domain

    7. XM_028828944.1 → XP_028684777.1  death domain-containing protein CRADD isoform X8

      Conserved Domains (1) summary
      cl14633
      Location:1 → 94
      DD; Death Domain Superfamily of protein-protein interaction domains

    8. XM_028828945.1 → XP_028684778.1  death domain-containing protein CRADD isoform X9

      Conserved Domains (1) summary
      cl14633
      Location:1 → 94
      DD; Death Domain Superfamily of protein-protein interaction domains

    9. XM_028828938.1 → XP_028684771.1  death domain-containing protein CRADD isoform X2

      Conserved Domains (1) summary
      cd08327
      Location:1 → 94
      CARD_RAIDD; Caspase activation and recruitment domain of RIP-associated ICH-1 homologous protein with a death domain

    RNA

    1. XR_003720452.1 RNA Sequence

    2. XR_003720454.1 RNA Sequence

    3. XR_003720453.1 RNA Sequence

    4. XR_003720451.1 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

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