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    TFEB transcription factor EB [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 694214, updated on 17-Aug-2024

    Summary

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    Official Symbol
    TFEBprovided by VGNC
    Official Full Name
    transcription factor EBprovided by VGNC
    Primary source
    VGNC:VGNC:78326
    See related
    Ensembl:ENSMMUG00000004690
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See TFEB in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 4 NC_041757.1 (127654390..127708200)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 4 NC_027896.1 (42647752..42698133, complement)

    Chromosome 4 - NC_041757.1Genomic Context describing neighboring genes Neighboring gene fibroblast growth factor receptor substrate 3 Neighboring gene progastricsin Neighboring gene MyoD family inhibitor Neighboring gene forkhead box P4

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein dimerization activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in humoral immune response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    transcription factor EB

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001266320.1 → NP_001253249.1  transcription factor EB

      See identical proteins and their annotated locations for NP_001253249.1

      Status: PROVISIONAL

      Source sequence(s)
      JU320705
      UniProtKB/TrEMBL
      F6RM40, F7FXN6, H9EQ02
      Related
      ENSMMUP00000078191.1, ENSMMUT00000088712.1
      Conserved Domains (3) summary
      cd18927
      Location:226 → 316
      bHLHzip_TFEB; basic Helix-Loop-Helix-zipper (bHLHzip) domain found in transcription factor EB (TFEB) and similar proteins
      pfam11851
      Location:321 → 473
      DUF3371; Domain of unknown function (DUF3371)
      pfam15951
      Location:4 → 162
      MITF_TFEB_C_3_N; MITF/TFEB/TFEC/TFE3 N-terminus

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041757.1 Reference Mmul_10 Primary Assembly

      Range
      127654390..127708200
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028846621.1 → XP_028702454.1  transcription factor EB isoform X1

      UniProtKB/TrEMBL
      F6WCA4
      Related
      ENSMMUP00000033708.3, ENSMMUT00000040665.3
      Conserved Domains (3) summary
      cd18927
      Location:240 → 330
      bHLHzip_TFEB; basic Helix-Loop-Helix-zipper (bHLHzip) domain found in transcription factor EB (TFEB) and similar proteins
      pfam11851
      Location:335 → 487
      DUF3371; Domain of unknown function (DUF3371)
      pfam15951
      Location:18 → 176
      MITF_TFEB_C_3_N; MITF/TFEB/TFEC/TFE3 N-terminus

    2. XM_028846622.1 → XP_028702455.1  transcription factor EB isoform X2

      UniProtKB/TrEMBL
      F6RM40, F7FXN6, H9EQ02
      Related
      ENSMMUP00000006232.3, ENSMMUT00000006623.4
      Conserved Domains (3) summary
      cd18927
      Location:226 → 316
      bHLHzip_TFEB; basic Helix-Loop-Helix-zipper (bHLHzip) domain found in transcription factor EB (TFEB) and similar proteins
      pfam11851
      Location:321 → 473
      DUF3371; Domain of unknown function (DUF3371)
      pfam15951
      Location:4 → 162
      MITF_TFEB_C_3_N; MITF/TFEB/TFEC/TFE3 N-terminus

    3. XM_028846623.1 → XP_028702456.1  transcription factor EB isoform X2

      UniProtKB/TrEMBL
      F6RM40, F7FXN6, H9EQ02
      Related
      ENSMMUP00000026068.4, ENSMMUT00000027863.4
      Conserved Domains (3) summary
      cd18927
      Location:226 → 316
      bHLHzip_TFEB; basic Helix-Loop-Helix-zipper (bHLHzip) domain found in transcription factor EB (TFEB) and similar proteins
      pfam11851
      Location:321 → 473
      DUF3371; Domain of unknown function (DUF3371)
      pfam15951
      Location:4 → 162
      MITF_TFEB_C_3_N; MITF/TFEB/TFEC/TFE3 N-terminus

    4. XM_028846624.1 → XP_028702457.1  transcription factor EB isoform X2

      UniProtKB/TrEMBL
      F6RM40, F7FXN6, H9EQ02
      Related
      ENSMMUP00000063962.1, ENSMMUT00000093067.1
      Conserved Domains (3) summary
      cd18927
      Location:226 → 316
      bHLHzip_TFEB; basic Helix-Loop-Helix-zipper (bHLHzip) domain found in transcription factor EB (TFEB) and similar proteins
      pfam11851
      Location:321 → 473
      DUF3371; Domain of unknown function (DUF3371)
      pfam15951
      Location:4 → 162
      MITF_TFEB_C_3_N; MITF/TFEB/TFEC/TFE3 N-terminus
    Nucleotide Protein
    Heading Accession and Version

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