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    SHC3 SHC adaptor protein 3 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 574275, updated on 17-Aug-2024

    Summary

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    Official Symbol
    SHC3provided by VGNC
    Official Full Name
    SHC adaptor protein 3provided by VGNC
    Primary source
    VGNC:VGNC:112115
    See related
    Ensembl:ENSMMUG00000039355
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See SHC3 in Genome Data Viewer
    Location:
    chromosome: 15
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 15 NC_041768.1 (104048144..104221219, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 15 NC_027907.1 (105248352..105418235, complement) , (105173589..105231269, complement) , (105135648..105143434, complement)

    Chromosome 15 - NC_041768.1Genomic Context describing neighboring genes Neighboring gene PEST proteolytic signal-containing nuclear protein pseudogene Neighboring gene uncharacterized LOC114672841 Neighboring gene uncharacterized LOC114672842 Neighboring gene sphingosine-1-phosphate receptor 3 Neighboring gene serine/threonine-protein phosphatase 4 regulatory subunit 2 pseudogene Neighboring gene uncharacterized LOC106993829 Neighboring gene CDC28 protein kinase regulatory subunit 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Elevated gene expression levels distinguish human from non-human primate brains. Cáceres M, et al. Proc Natl Acad Sci U S A, 2003 Oct 28. PMID 14557539, Free PMC Article
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables receptor tyrosine kinase binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell surface receptor protein tyrosine kinase signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    SHC-transforming protein 3
    Names
    SHC (Src homology 2 domain containing) transforming protein 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001265690.1 → NP_001252619.1  SHC-transforming protein 3

      See identical proteins and their annotated locations for NP_001252619.1

      Status: PROVISIONAL

      Source sequence(s)
      JV667417
      UniProtKB/TrEMBL
      A0A1D5QMQ1, F6W915
      Related
      ENSMMUP00000049326.2, ENSMMUT00000079013.2
      Conserved Domains (2) summary
      cd09925
      Location:496 → 598
      SH2_SHC; Src homology 2 (SH2) domain found in SH2 adaptor protein C (SHC)
      cd01209
      Location:139 → 310
      PTB_Shc; Shc-like phosphotyrosine-binding (PTB) domain

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041768.1 Reference Mmul_10 Primary Assembly

      Range
      104048144..104221219 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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    Molecular Biology Databases
    Research Materials