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    FHL2 four and a half LIM domains 2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 713222, updated on 17-Aug-2024

    Summary

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    Official Symbol
    FHL2provided by VGNC
    Official Full Name
    four and a half LIM domains 2provided by VGNC
    Primary source
    VGNC:VGNC:72661
    Locus tag
    EGK_05645
    See related
    Ensembl:ENSMMUG00000016594
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See FHL2 in Genome Data Viewer
    Location:
    chromosome: 13
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 13 NC_041766.1 (9108839..9185895, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 13 NC_027905.1 (100792266..100870525, complement)

    Chromosome 13 - NC_041766.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106993106 Neighboring gene chromosome 13 C2orf49 homolog Neighboring gene uncharacterized LOC114671894 Neighboring gene NCK adaptor protein 2 Neighboring gene uncharacterized LOC114671895 Neighboring gene ECRG4 augurin precursor Neighboring gene UDP-glucuronate decarboxylase 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables transcription coregulator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables transcription factor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of calcineurin-NFAT signaling cascade IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in Z disc IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    four and a half LIM domains protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041766.1 Reference Mmul_10 Primary Assembly

      Range
      9108839..9185895 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028832267.1 → XP_028688100.1  four and a half LIM domains protein 2 isoform X4

      Conserved Domains (3) summary
      cd09431
      Location:48 → 104
      LIM3_Fhl2; The third LIM domain of Four and a half LIM domains protein 2 (FHL2)
      cd09433
      Location:107 → 164
      LIM4_FHL2; The fourth LIM domain of Four and a half LIM domains protein 2 (FHL2)
      cl02475
      Location:1 → 43
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

    2. XM_001109039.4 → XP_001109039.1  four and a half LIM domains protein 2 isoform X3

      See identical proteins and their annotated locations for XP_001109039.1

      UniProtKB/TrEMBL
      A0A8J8XKI4, G7NAU8, H9Z135
      Conserved Domains (5) summary
      cd09422
      Location:36 → 97
      LIM1_FHL2; The first LIM domain of Four and a half LIM domains protein 2 (FHL2)
      cd09426
      Location:101 → 157
      LIM2_FHL2; The second LIM domain of Four and a half LIM domains protein 2 (FHL2)
      cd09431
      Location:162 → 218
      LIM3_Fhl2; The third LIM domain of Four and a half LIM domains protein 2 (FHL2)
      cd09433
      Location:221 → 278
      LIM4_FHL2; The fourth LIM domain of Four and a half LIM domains protein 2 (FHL2)
      cl02475
      Location:5 → 33
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

    3. XM_015113044.2 → XP_014968530.1  four and a half LIM domains protein 2 isoform X3

      UniProtKB/TrEMBL
      A0A8J8XKI4, G7NAU8, H9Z135
      Conserved Domains (5) summary
      cd09422
      Location:36 → 97
      LIM1_FHL2; The first LIM domain of Four and a half LIM domains protein 2 (FHL2)
      cd09426
      Location:101 → 157
      LIM2_FHL2; The second LIM domain of Four and a half LIM domains protein 2 (FHL2)
      cd09431
      Location:162 → 218
      LIM3_Fhl2; The third LIM domain of Four and a half LIM domains protein 2 (FHL2)
      cd09433
      Location:221 → 278
      LIM4_FHL2; The fourth LIM domain of Four and a half LIM domains protein 2 (FHL2)
      cl02475
      Location:5 → 33
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

    4. XM_001109260.4 → XP_001109260.1  four and a half LIM domains protein 2 isoform X2

      See identical proteins and their annotated locations for XP_001109260.1

      Conserved Domains (5) summary
      cd09422
      Location:129 → 190
      LIM1_FHL2; The first LIM domain of Four and a half LIM domains protein 2 (FHL2)
      cd09426
      Location:194 → 250
      LIM2_FHL2; The second LIM domain of Four and a half LIM domains protein 2 (FHL2)
      cd09431
      Location:255 → 311
      LIM3_Fhl2; The third LIM domain of Four and a half LIM domains protein 2 (FHL2)
      cd09433
      Location:314 → 371
      LIM4_FHL2; The fourth LIM domain of Four and a half LIM domains protein 2 (FHL2)
      cl02475
      Location:98 → 126
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

    5. XM_028832268.1 → XP_028688101.1  four and a half LIM domains protein 2 isoform X4

      Conserved Domains (3) summary
      cd09431
      Location:48 → 104
      LIM3_Fhl2; The third LIM domain of Four and a half LIM domains protein 2 (FHL2)
      cd09433
      Location:107 → 164
      LIM4_FHL2; The fourth LIM domain of Four and a half LIM domains protein 2 (FHL2)
      cl02475
      Location:1 → 43
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

    6. XM_001109208.4 → XP_001109208.2  four and a half LIM domains protein 2 isoform X1

      UniProtKB/TrEMBL
      F6U4Q6
      Related
      ENSMMUP00000021812.4, ENSMMUT00000023312.4
      Conserved Domains (5) summary
      cd09422
      Location:146 → 207
      LIM1_FHL2; The first LIM domain of Four and a half LIM domains protein 2 (FHL2)
      cd09426
      Location:211 → 267
      LIM2_FHL2; The second LIM domain of Four and a half LIM domains protein 2 (FHL2)
      cd09431
      Location:272 → 328
      LIM3_Fhl2; The third LIM domain of Four and a half LIM domains protein 2 (FHL2)
      cd09433
      Location:331 → 388
      LIM4_FHL2; The fourth LIM domain of Four and a half LIM domains protein 2 (FHL2)
      cl02475
      Location:115 → 143
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
    Nucleotide Protein
    Heading Accession and Version

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