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    SEMA4D semaphorin 4D [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 697697, updated on 17-Aug-2024

    Summary

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    Official Symbol
    SEMA4Dprovided by VGNC
    Official Full Name
    semaphorin 4Dprovided by VGNC
    Primary source
    VGNC:VGNC:77166
    See related
    Ensembl:ENSMMUG00000008629
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See SEMA4D in Genome Data Viewer
    Location:
    chromosome: 15
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 15 NC_041768.1 (104408091..104543051, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 15 NC_027907.1 (105624467..105702540, complement)

    Chromosome 15 - NC_041768.1Genomic Context describing neighboring genes Neighboring gene SECIS binding protein 2 Neighboring gene CDC28 protein kinase regulatory subunit 2 Neighboring gene proliferation-associated protein 2G4-like Neighboring gene growth arrest and DNA damage inducible gamma Neighboring gene uncharacterized LOC114672843

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables chemorepellent activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables semaphorin receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in axon guidance IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative chemotaxis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of alkaline phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of axon extension involved in axon guidance IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in neural crest cell migration IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in ossification involved in bone maturation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of cell migration IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in semaphorin-plexin signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    semaphorin-4D

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041768.1 Reference Mmul_10 Primary Assembly

      Range
      104408091..104543051 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028835312.1 → XP_028691145.1  semaphorin-4D isoform X3

      UniProtKB/TrEMBL
      F6VZ03, H9FNR9
      Related
      ENSMMUP00000038913.3, ENSMMUT00000045874.3
      Conserved Domains (3) summary
      cd11259
      Location:31 → 501
      Sema_4D; The Sema domain, a protein interacting module, of semaphorin 4D (Sema4D, also known as CD100)
      smart00423
      Location:503 → 554
      PSI; domain found in Plexins, Semaphorins and Integrins
      cl11960
      Location:622 → 679
      Ig; Immunoglobulin domain

    2. XM_015118066.2 → XP_014973552.2  semaphorin-4D isoform X1

      UniProtKB/TrEMBL
      A0A8J8Y3Y5, F7FCM4, G7NEM8, H9FNS0
      Related
      ENSMMUP00000011320.3, ENSMMUT00000012067.4
      Conserved Domains (3) summary
      cd05873
      Location:559 → 645
      Ig_Sema4D_like; Immunoglobulin (Ig)-like domain of the class IV semaphorin Sema4D
      cd11259
      Location:31 → 501
      Sema_4D; The Sema domain, a protein interacting module, of semaphorin 4D (Sema4D, also known as CD100)
      smart00423
      Location:503 → 554
      PSI; domain found in Plexins, Semaphorins and Integrins

    3. XM_028835310.1 → XP_028691143.1  semaphorin-4D isoform X2

      UniProtKB/TrEMBL
      A0A8J8Y3Y5, G7NEM8, H9FNS0
      Conserved Domains (3) summary
      cd05873
      Location:530 → 616
      Ig_Sema4D_like; Immunoglobulin (Ig)-like domain of the class IV semaphorin Sema4D
      smart00423
      Location:474 → 525
      PSI; domain found in Plexins, Semaphorins and Integrins
      cl15693
      Location:31 → 472
      Sema; The Sema domain, a protein interacting module, of semaphorins and plexins

    4. XM_015118062.2 → XP_014973548.2  semaphorin-4D isoform X1

      UniProtKB/TrEMBL
      A0A8J8Y3Y5, F7FCM4, G7NEM8, H9FNS0
      Related
      ENSMMUP00000078848.1, ENSMMUT00000095301.1
      Conserved Domains (3) summary
      cd05873
      Location:559 → 645
      Ig_Sema4D_like; Immunoglobulin (Ig)-like domain of the class IV semaphorin Sema4D
      cd11259
      Location:31 → 501
      Sema_4D; The Sema domain, a protein interacting module, of semaphorin 4D (Sema4D, also known as CD100)
      smart00423
      Location:503 → 554
      PSI; domain found in Plexins, Semaphorins and Integrins

    5. XM_028835309.1 → XP_028691142.1  semaphorin-4D isoform X1

      UniProtKB/TrEMBL
      A0A8J8Y3Y5, F7FCM4, G7NEM8, H9FNS0
      Conserved Domains (3) summary
      cd05873
      Location:559 → 645
      Ig_Sema4D_like; Immunoglobulin (Ig)-like domain of the class IV semaphorin Sema4D
      cd11259
      Location:31 → 501
      Sema_4D; The Sema domain, a protein interacting module, of semaphorin 4D (Sema4D, also known as CD100)
      smart00423
      Location:503 → 554
      PSI; domain found in Plexins, Semaphorins and Integrins

    6. XM_028835311.1 → XP_028691144.1  semaphorin-4D isoform X3

      UniProtKB/TrEMBL
      F6VZ03, H9FNR9
      Conserved Domains (3) summary
      cd11259
      Location:31 → 501
      Sema_4D; The Sema domain, a protein interacting module, of semaphorin 4D (Sema4D, also known as CD100)
      smart00423
      Location:503 → 554
      PSI; domain found in Plexins, Semaphorins and Integrins
      cl11960
      Location:622 → 679
      Ig; Immunoglobulin domain

    7. XM_028835313.1 → XP_028691146.1  semaphorin-4D isoform X4

      UniProtKB/TrEMBL
      H9FNR9
      Conserved Domains (2) summary
      cd11259
      Location:31 → 501
      Sema_4D; The Sema domain, a protein interacting module, of semaphorin 4D (Sema4D, also known as CD100)
      smart00423
      Location:503 → 554
      PSI; domain found in Plexins, Semaphorins and Integrins

    8. XM_015118064.2 → XP_014973550.2  semaphorin-4D isoform X1

      UniProtKB/TrEMBL
      A0A8J8Y3Y5, F7FCM4, G7NEM8, H9FNS0
      Related
      ENSMMUP00000067860.1, ENSMMUT00000101226.1
      Conserved Domains (3) summary
      cd05873
      Location:559 → 645
      Ig_Sema4D_like; Immunoglobulin (Ig)-like domain of the class IV semaphorin Sema4D
      cd11259
      Location:31 → 501
      Sema_4D; The Sema domain, a protein interacting module, of semaphorin 4D (Sema4D, also known as CD100)
      smart00423
      Location:503 → 554
      PSI; domain found in Plexins, Semaphorins and Integrins

    9. XM_028835314.1 → XP_028691147.1  semaphorin-4D isoform X4

      UniProtKB/TrEMBL
      H9FNR9
      Conserved Domains (2) summary
      cd11259
      Location:31 → 501
      Sema_4D; The Sema domain, a protein interacting module, of semaphorin 4D (Sema4D, also known as CD100)
      smart00423
      Location:503 → 554
      PSI; domain found in Plexins, Semaphorins and Integrins
    Nucleotide Protein
    Heading Accession and Version

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