RLN2 relaxin 2 [Macaca mulatta (Rhesus monkey)] - Gene

Summary

Gene symbol: RLN2
Gene description: relaxin 2
Locus tag: EGK_07726
See related: Ensembl:ENSMMUG00000047971
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Macaca mulatta
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Also known as: RLN1
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Genomic context

Location:: chromosome: 15

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
103	current	Mmul_10 (GCF_003339765.1)	15	NC_041768.1 (78458510..78461684)
102	previous assembly	Mmul_8.0.1 (GCF_000772875.2)	15	NC_027907.1 (79122520..79125694)

Chromosome 15 - NC_041768.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

We established a non-human primate model of early human pregnancy to study the effects of relaxin in vivo.
Title: Reproductive tract actions of relaxin in models of human pregnancy.
Relaxin actions in pregnancy include increasing cervical pro-MMP-1 and pro-MMP-3 and decreasing TIMP-1, changes which soften the cervix.
Title: Relaxin and the control of primate parturition.

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables hormone activity	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in extracellular region	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: prorelaxin H2

Names: relaxin 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001115126.1 → NP_001108598.1 prorelaxin H2 precursor

See identical proteins and their annotated locations for NP_001108598.1

Status: PROVISIONAL

Source sequence(s)

EU437443

UniProtKB/Swiss-Prot

P19884

UniProtKB/TrEMBL

A0A8J8XWZ2, B1AAP6, G7NG72

Related

ENSMMUP00000053647.1, ENSMMUT00000063515.2

Conserved Domains (2) summary

cd04365
Location:146 → 185

IlGF_relaxin_like; IlGF_like family, relaxin_like subgroup, specific to vertebrates. Members include a number of active peptides including (pro)relaxin, mammalian Leydig cell-specific insulin-like peptide (gene INSL3), early placenta insulin-like peptide (ELIP; gene INSL4), ...

cl02453
Location:32 → 71

IlGF_like; Insulin/insulin-like growth factor/relaxin family; insulin family of proteins. Members include a number of active peptides which are evolutionary related including insulin, relaxin, prorelaxin, insulin-like growth factors I and II, mammalian Leydig ...