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    SIM1 SIM bHLH transcription factor 1 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 695324, updated on 17-Aug-2024

    Summary

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    Official Symbol
    SIM1provided by VGNC
    Official Full Name
    SIM bHLH transcription factor 1provided by VGNC
    Primary source
    VGNC:VGNC:77217
    Locus tag
    EGK_15194
    See related
    Ensembl:ENSMMUG00000022285
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See SIM1 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 4 NC_041757.1 (72838369..72913938)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 4 NC_027896.1 (98924517..98999850, complement)

    Chromosome 4 - NC_041757.1Genomic Context describing neighboring genes Neighboring gene MAPK-interacting and spindle-stabilizing protein-like Neighboring gene activating signal cointegrator 1 complex subunit 3 Neighboring gene DCN1-like protein 1 pseudogene Neighboring gene uncharacterized LOC106998051 Neighboring gene arginase-2, mitochondrial pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein dimerization activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    single-minded homolog 1
    Names
    single-minded family bHLH transcription factor 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041757.1 Reference Mmul_10 Primary Assembly

      Range
      72838369..72913938
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015136983.2 → XP_014992469.1  single-minded homolog 1

      UniProtKB/TrEMBL
      A0A663D7X0, A0A8J8YN00, F6X815, G7MPZ5
      Related
      ENSMMUP00000029336.3, ENSMMUT00000031352.4
      Conserved Domains (5) summary
      cd00083
      Location:2 → 52
      HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
      cd00130
      Location:229 → 328
      PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...
      pfam00989
      Location:79 → 141
      PAS; PAS fold
      pfam06621
      Location:360 → 669
      SIM_C; Single-minded protein C-terminus
      pfam08447
      Location:243 → 329
      PAS_3; PAS fold
    Nucleotide Protein
    Heading Accession and Version

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