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    NEIL2 nei like DNA glycosylase 2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 696647, updated on 17-Aug-2024

    Summary

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    Official Symbol
    NEIL2provided by VGNC
    Official Full Name
    nei like DNA glycosylase 2provided by VGNC
    Primary source
    VGNC:VGNC:75210
    See related
    Ensembl:ENSMMUG00000019209
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See NEIL2 in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 8 NC_041761.1 (8788098..8807133, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 8 NC_027900.1 (7944703..7963775, complement)

    Chromosome 8 - NC_041761.1Genomic Context describing neighboring genes Neighboring gene farnesyl-diphosphate farnesyltransferase 1 Neighboring gene activated RNA polymerase II transcriptional coactivator p15 pseudogene Neighboring gene long intergenic non-protein coding RNA 2905 Neighboring gene GATA binding protein 4

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA N-glycosylase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables DNA-(apurinic or apyrimidinic site) endonuclease activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables damaged DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in base-excision repair IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    endonuclease 8-like 2
    Names
    nei endonuclease VIII-like 2
    nei like 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041761.1 Reference Mmul_10 Primary Assembly

      Range
      8788098..8807133 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015144748.2 → XP_015000234.1  endonuclease 8-like 2 isoform X2

      UniProtKB/TrEMBL
      H9FSB8
      Conserved Domains (3) summary
      COG0266
      Location:94 → 259
      Nei; Formamidopyrimidine-DNA glycosylase [Replication, recombination and repair]
      pfam06831
      Location:159 → 205
      H2TH; Formamidopyrimidine-DNA glycosylase H2TH domain
      cl03119
      Location:62 → 124
      FpgNei_N; N-terminal domain of Fpg (formamidopyrimidine-DNA glycosylase, MutM)_Nei (endonuclease VIII) base-excision repair DNA glycosylases

    2. XM_015144745.2 → XP_015000231.2  endonuclease 8-like 2 isoform X1

      UniProtKB/TrEMBL
      F6QQ86, G7N0H4
      Related
      ENSMMUP00000025245.2, ENSMMUT00000026984.3
      Conserved Domains (2) summary
      cd08968
      Location:1 → 185
      MeNeil2_N; N-terminal domain of metazoan Nei-like glycosylase 2 (NEIL2)
      COG0266
      Location:155 → 320
      Nei; Formamidopyrimidine-DNA glycosylase [Replication, recombination and repair]

    3. XM_015144746.2 → XP_015000232.2  endonuclease 8-like 2 isoform X1

      UniProtKB/TrEMBL
      F6QQ86, G7N0H4
      Related
      ENSMMUP00000047365.2, ENSMMUT00000063676.2
      Conserved Domains (2) summary
      cd08968
      Location:1 → 185
      MeNeil2_N; N-terminal domain of metazoan Nei-like glycosylase 2 (NEIL2)
      COG0266
      Location:155 → 320
      Nei; Formamidopyrimidine-DNA glycosylase [Replication, recombination and repair]

    4. XM_015144747.2 → XP_015000233.2  endonuclease 8-like 2 isoform X1

      UniProtKB/TrEMBL
      F6QQ86, G7N0H4
      Conserved Domains (2) summary
      cd08968
      Location:1 → 185
      MeNeil2_N; N-terminal domain of metazoan Nei-like glycosylase 2 (NEIL2)
      COG0266
      Location:155 → 320
      Nei; Formamidopyrimidine-DNA glycosylase [Replication, recombination and repair]
    Nucleotide Protein
    Heading Accession and Version

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