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    APOBEC3H apolipoprotein B mRNA editing enzyme catalytic subunit 3H [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 723811, updated on 17-Aug-2024

    Summary

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    Official Symbol
    APOBEC3Hprovided by VGNC
    Official Full Name
    apolipoprotein B mRNA editing enzyme catalytic subunit 3Hprovided by VGNC
    Primary source
    VGNC:VGNC:69894
    See related
    Ensembl:ENSMMUG00000001016
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See APOBEC3H in Genome Data Viewer
    Location:
    chromosome: 10
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 10 NC_041763.1 (12471710..12484284, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 10 NC_027902.1 (81065782..81078161)

    Chromosome 10 - NC_041763.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107000666 Neighboring gene platelet derived growth factor subunit B Neighboring gene chromobox 7 Neighboring gene apolipoprotein B mRNA editing enzyme catalytic subunit 3G Neighboring gene apolipoprotein B mRNA editing enzyme catalytic subunit 3F

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Adaptive evolution and antiviral activity of the conserved mammalian cytidine deaminase APOBEC3H. OhAinle M, et al. J Virol, 2006 Apr. PMID 16571802, Free PMC Article
    2. Analysis of the N-terminal positively charged residues of the simian immunodeficiency virus Vif reveals a critical amino acid required for the antagonism of rhesus APOBEC3D, G, and H. Schmitt K, et al. Virology, 2014 Jan 20. PMID 24418547, Free PMC Article
    3. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The arginine at position 14 of the SIV Vif is a critical residue for virus restriction by rhA3D, rhA3G and rhA3H.
      Title: Analysis of the N-terminal positively charged residues of the simian immunodeficiency virus Vif reveals a critical amino acid required for the antagonism of rhesus APOBEC3D, G, and H.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables cytidine deaminase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in DNA cytosine deamination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cytidine to uridine editing IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in defense response to virus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of single stranded viral RNA replication via double stranded DNA intermediate IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in P-body IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    DNA dC->dU-editing enzyme APOBEC-3H
    Names
    apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3H
    NP_001332864.1
    XP_015005829.2
    XP_028683301.1
    XP_028683302.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001345935.1 → NP_001332864.1  DNA dC->dU-editing enzyme APOBEC-3H

      Status: VALIDATED

      Source sequence(s)
      JU481501, JV053406
      UniProtKB/Swiss-Prot
      Q19Q52
      Related
      ENSMMUP00000053576.2, ENSMMUT00000069638.2

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041763.1 Reference Mmul_10 Primary Assembly

      Range
      12471710..12484284 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028827468.1 → XP_028683301.1  DNA dC->dU-editing enzyme APOBEC-3H isoform X1

      UniProtKB/Swiss-Prot
      Q19Q52
      Conserved Domains (1) summary
      pfam08210
      Location:9 → 179
      APOBEC_N; APOBEC-like N-terminal domain

    2. XM_028827469.1 → XP_028683302.1  DNA dC->dU-editing enzyme APOBEC-3H isoform X1

      UniProtKB/Swiss-Prot
      Q19Q52
      Conserved Domains (1) summary
      pfam08210
      Location:9 → 179
      APOBEC_N; APOBEC-like N-terminal domain

    3. XM_015150343.2 → XP_015005829.2  DNA dC->dU-editing enzyme APOBEC-3H isoform X1

      UniProtKB/Swiss-Prot
      Q19Q52
      Conserved Domains (1) summary
      pfam08210
      Location:9 → 179
      APOBEC_N; APOBEC-like N-terminal domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q19Q52.1 GenPept UniProtKB/Swiss-Prot:Q19Q52

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.