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    FOXP2 forkhead box P2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 613237, updated on 17-Aug-2024

    Summary

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    Official Symbol
    FOXP2provided by VGNC
    Official Full Name
    forkhead box P2provided by VGNC
    Primary source
    VGNC:VGNC:72720
    See related
    Ensembl:ENSMMUG00000008005
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See FOXP2 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    24
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 3 NC_041756.1 (140320963..140912806)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 3 NC_027895.1 (139602847..140196871)

    Chromosome 3 - NC_041756.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC114676764 Neighboring gene protein phosphatase 1 regulatory subunit 3A Neighboring gene 60S ribosomal protein L36 pseudogene Neighboring gene MyoD family inhibitor domain containing Neighboring gene small nucleolar RNA SNORA25

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Molecular evolution of FOXP2, a gene involved in speech and language. Enard W, et al. Nature, 2002 Aug 22. PMID 12192408
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription repressor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    forkhead box protein P2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001033021.1 → NP_001028193.1  forkhead box protein P2

      See identical proteins and their annotated locations for NP_001028193.1

      Status: PROVISIONAL

      Source sequence(s)
      AF512950
      UniProtKB/Swiss-Prot
      Q8MJ97
      Related
      ENSMMUP00000010501.3, ENSMMUT00000011202.3
      Conserved Domains (3) summary
      COG5025
      Location:476 → 707
      COG5025; Transcription factor of the Forkhead/HNF3 family [Transcription]
      pfam16159
      Location:341 → 408
      FOXP-CC; FOXP coiled-coil domain
      cd20065
      Location:502 → 583
      FH_FOXP2; Forkhead (FH) domain found in Forkhead box protein P2 (FOXP2)

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041756.1 Reference Mmul_10 Primary Assembly

      Range
      140320963..140912806
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028844760.1 → XP_028700593.1  forkhead box protein P2 isoform X1

      Conserved Domains (3) summary
      COG5025
      Location:518 → 749
      COG5025; Transcription factor of the Forkhead/HNF3 family [Transcription]
      pfam16159
      Location:383 → 450
      FOXP-CC; FOXP coiled-coil domain
      cd20065
      Location:544 → 625
      FH_FOXP2; Forkhead (FH) domain found in Forkhead box protein P2 (FOXP2)

    2. XM_028844761.1 → XP_028700594.1  forkhead box protein P2 isoform X3

      Conserved Domains (3) summary
      COG5025
      Location:493 → 724
      COG5025; Transcription factor of the Forkhead/HNF3 family [Transcription]
      pfam16159
      Location:358 → 425
      FOXP-CC; FOXP coiled-coil domain
      cd20065
      Location:519 → 600
      FH_FOXP2; Forkhead (FH) domain found in Forkhead box protein P2 (FOXP2)

    3. XM_015134716.2 → XP_014990202.1  forkhead box protein P2 isoform X2

      UniProtKB/TrEMBL
      A0A1I7Q461
      Related
      ENSMMUP00000010512.4, ENSMMUT00000011213.4
      Conserved Domains (3) summary
      COG5025
      Location:501 → 732
      COG5025; Transcription factor of the Forkhead/HNF3 family [Transcription]
      pfam16159
      Location:366 → 433
      FOXP-CC; FOXP coiled-coil domain
      cd20065
      Location:527 → 608
      FH_FOXP2; Forkhead (FH) domain found in Forkhead box protein P2 (FOXP2)

    4. XM_015134717.2 → XP_014990203.1  forkhead box protein P2 isoform X4

      UniProtKB/Swiss-Prot
      Q8MJ97
      Conserved Domains (3) summary
      COG5025
      Location:476 → 707
      COG5025; Transcription factor of the Forkhead/HNF3 family [Transcription]
      pfam16159
      Location:341 → 408
      FOXP-CC; FOXP coiled-coil domain
      cd20065
      Location:502 → 583
      FH_FOXP2; Forkhead (FH) domain found in Forkhead box protein P2 (FOXP2)

    5. XM_015134718.2 → XP_014990204.1  forkhead box protein P2 isoform X5

      Conserved Domains (3) summary
      COG5025
      Location:384 → 615
      COG5025; Transcription factor of the Forkhead/HNF3 family [Transcription]
      cd00059
      Location:411 → 483
      FH; Forkhead (FH), also known as a "winged helix". FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA as ...
      pfam16159
      Location:249 → 316
      FOXP-CC; FOXP coiled-coil domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8MJ97.1 GenPept UniProtKB/Swiss-Prot:Q8MJ97

    Gene LinkOut

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