SPEG striated muscle enriched protein kinase [Macaca mulatta (Rhesus monkey)] - Gene

Summary

Official Symbol: SPEGprovided by VGNC
Official Full Name: striated muscle enriched protein kinaseprovided by VGNC
Primary source: VGNC:VGNC:99406
See related: Ensembl:ENSMMUG00000017936
Gene type: protein coding
RefSeq status: MODEL
Organism: Macaca mulatta
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 12

Exon count:: 50

Annotation release	Status	Assembly	Chr	Location
103	current	Mmul_10 (GCF_003339765.1)	12	NC_041765.1 (106865719..106924694)
102	previous assembly	Mmul_8.0.1 (GCF_000772875.2)	12	NC_027904.1 (101559150..101618019)

Chromosome 12 - NC_041765.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

REN53061 (e-PCR)
- UniSTS:377861

REN53062 (e-PCR)
- UniSTS:377862

REN53063 (e-PCR)
- UniSTS:377863

REN53066 (e-PCR)
- UniSTS:377866

ECD10556 (e-PCR)
- UniSTS:291595

REN53067 (e-PCR)
- UniSTS:377867

REN53068 (e-PCR)
- UniSTS:377868

REN53071 (e-PCR)
- UniSTS:377871

REN53072 (e-PCR)
- UniSTS:377872

ECD11590 (e-PCR)
- UniSTS:292626

REN53074 (e-PCR)
- UniSTS:377874

ECD14937 (e-PCR)
- UniSTS:295955

REN53076 (e-PCR)
- UniSTS:377876

REN53078 (e-PCR)
- UniSTS:377878

REN53079 (e-PCR)
- UniSTS:377879

REN53081 (e-PCR)
- UniSTS:377881

REN53082 (e-PCR)
- UniSTS:377882

REN53083 (e-PCR)
- UniSTS:377883

REN53085 (e-PCR)
- UniSTS:377885

REN53086 (e-PCR)
- UniSTS:377886

REN53087 (e-PCR)
- UniSTS:377887

ECD19831 (e-PCR)
- UniSTS:300835

REN53091 (e-PCR)
- UniSTS:377891

REN53092 (e-PCR)
- UniSTS:377892

REN53093 (e-PCR)
- UniSTS:377893

REN53094 (e-PCR)
- UniSTS:377894

REN53096 (e-PCR)
- UniSTS:377896

ECD05962 (e-PCR)
- UniSTS:287024

ECD04674 (e-PCR)
- UniSTS:285745

ECD04675 (e-PCR)
- UniSTS:285746

REN52850 (e-PCR)
- UniSTS:377650

ECD22423 (e-PCR)
- UniSTS:303411

REN52851 (e-PCR)
- UniSTS:377651

REN52852 (e-PCR)
- UniSTS:377652

ECD07252 (e-PCR)
- UniSTS:288309

REN52853 (e-PCR)
- UniSTS:377653

SGC30668 (e-PCR)
- UniSTS:31030

ECD14714 (e-PCR)
- UniSTS:295734

REN52854 (e-PCR)
- UniSTS:377654

REN52855 (e-PCR)
- UniSTS:377655

REN52856 (e-PCR)
- UniSTS:377656

ECD12401 (e-PCR)
- UniSTS:293434

ECD12402 (e-PCR)
- UniSTS:293435

REN52859 (e-PCR)
- UniSTS:377659

REN52860 (e-PCR)
- UniSTS:377660

REN52861 (e-PCR)
- UniSTS:377661

REN52863 (e-PCR)
- UniSTS:377663

REN52864 (e-PCR)
- UniSTS:377664

REN52865 (e-PCR)
- UniSTS:377665

REN52866 (e-PCR)
- UniSTS:377666

REN52867 (e-PCR)
- UniSTS:377667

REN52868 (e-PCR)
- UniSTS:377668

stSG632995 (e-PCR)
- UniSTS:460359

REN52871 (e-PCR)
- UniSTS:377671

REN52872 (e-PCR)
- UniSTS:377672

REN52873 (e-PCR)
- UniSTS:377673

stSG633000 (e-PCR)
- UniSTS:460362

ECD13444 (e-PCR)
- UniSTS:294474

stSG633001 (e-PCR)
- UniSTS:460363

REN52875 (e-PCR)
- UniSTS:377675

stSG633002 (e-PCR)
- UniSTS:460364

REN52876 (e-PCR)
- UniSTS:377676

ECD17304 (e-PCR)
- UniSTS:298317

ECD20903 (e-PCR)
- UniSTS:301901

REN52877 (e-PCR)
- UniSTS:377677

stSG633004 (e-PCR)
- UniSTS:460366

REN52878 (e-PCR)
- UniSTS:377678

stSG633005 (e-PCR)
- UniSTS:460367

REN52879 (e-PCR)
- UniSTS:377679

REN52880 (e-PCR)
- UniSTS:377680

REN52881 (e-PCR)
- UniSTS:377681

REN52882 (e-PCR)
- UniSTS:377682

stSG633009 (e-PCR)
- UniSTS:460371

stSG633010 (e-PCR)
- UniSTS:460372

stSG633011 (e-PCR)
- UniSTS:460373

REN52885 (e-PCR)
- UniSTS:377685

stSG633012 (e-PCR)
- UniSTS:460374

stSG633013 (e-PCR)
- UniSTS:460375

REN52887 (e-PCR)
- UniSTS:377687

stSG633014 (e-PCR)
- UniSTS:460376

REN52888 (e-PCR)
- UniSTS:377688

stSG633015 (e-PCR)
- UniSTS:460377

stSG633016 (e-PCR)
- UniSTS:460378

ECD12433 (e-PCR)
- UniSTS:293466

REN52891 (e-PCR)
- UniSTS:377691

REN52892 (e-PCR)
- UniSTS:377692

stSG633020 (e-PCR)
- UniSTS:460382

REN52894 (e-PCR)
- UniSTS:377694

stSG633023 (e-PCR)
- UniSTS:460383

REN52895 (e-PCR)
- UniSTS:377695

stSG633024 (e-PCR)
- UniSTS:460384

stSG633025 (e-PCR)
- UniSTS:460385

REN52897 (e-PCR)
- UniSTS:377697

stSG633026 (e-PCR)
- UniSTS:460386

REN52899 (e-PCR)
- UniSTS:377699

stSG633030 (e-PCR)
- UniSTS:460388

REN52900 (e-PCR)
- UniSTS:377700

ECD00591 (e-PCR)
- UniSTS:281701

REN52901 (e-PCR)
- UniSTS:377701

REN52903 (e-PCR)
- UniSTS:377703

REN52905 (e-PCR)
- UniSTS:377705

stSG633041 (e-PCR)
- UniSTS:460398

REN52912 (e-PCR)
- UniSTS:377712

ECD03710 (e-PCR)
- UniSTS:284790

REN52920 (e-PCR)
- UniSTS:377720

REN52922 (e-PCR)
- UniSTS:377722

REN52924 (e-PCR)
- UniSTS:377724

ECD09646 (e-PCR)
- UniSTS:290687

REN52933 (e-PCR)
- UniSTS:377733

ECD04240 (e-PCR)
- UniSTS:285318

REN52934 (e-PCR)
- UniSTS:377734

REN52938 (e-PCR)
- UniSTS:377738

REN52939 (e-PCR)
- UniSTS:377739

REN52945 (e-PCR)
- UniSTS:377745

REN52949 (e-PCR)
- UniSTS:377749

REN52950 (e-PCR)
- UniSTS:377750

REN52951 (e-PCR)
- UniSTS:377751

REN52953 (e-PCR)
- UniSTS:377753

ECD02968 (e-PCR)
- UniSTS:284058

STS-U57099 (e-PCR)
- UniSTS:33691

REN52955 (e-PCR)
- UniSTS:377755

REN52956 (e-PCR)
- UniSTS:377756

REN52960 (e-PCR)
- UniSTS:377760

REN52961 (e-PCR)
- UniSTS:377761

ECD01685 (e-PCR)
- UniSTS:282786

REN52962 (e-PCR)
- UniSTS:377762

REN52963 (e-PCR)
- UniSTS:377763

REN52965 (e-PCR)
- UniSTS:377765

REN52966 (e-PCR)
- UniSTS:377766

REN52967 (e-PCR)
- UniSTS:377767

REN52968 (e-PCR)
- UniSTS:377768

REN52969 (e-PCR)
- UniSTS:377769

ECD02212 (e-PCR)
- UniSTS:283312

REN52976 (e-PCR)
- UniSTS:377776

ECD14839 (e-PCR)
- UniSTS:295859

REN52980 (e-PCR)
- UniSTS:377780

REN52981 (e-PCR)
- UniSTS:377781

REN52982 (e-PCR)
- UniSTS:377782

REN52984 (e-PCR)
- UniSTS:377784

REN52986 (e-PCR)
- UniSTS:377786

REN52987 (e-PCR)
- UniSTS:377787

REN52988 (e-PCR)
- UniSTS:377788

REN52989 (e-PCR)
- UniSTS:377789

REN52990 (e-PCR)
- UniSTS:377790

ECD07910 (e-PCR)
- UniSTS:288960

ECD13049 (e-PCR)
- UniSTS:294080

REN52995 (e-PCR)
- UniSTS:377795

REN52996 (e-PCR)
- UniSTS:377796

REN52997 (e-PCR)
- UniSTS:377797

REN53001 (e-PCR)
- UniSTS:377801

REN53004 (e-PCR)
- UniSTS:377804

REN53005 (e-PCR)
- UniSTS:377805

REN53007 (e-PCR)
- UniSTS:377807

REN53008 (e-PCR)
- UniSTS:377808

REN53012 (e-PCR)
- UniSTS:377812

ECD01221 (e-PCR)
- UniSTS:282328

REN53019 (e-PCR)
- UniSTS:377819

REN53020 (e-PCR)
- UniSTS:377820

REN53022 (e-PCR)
- UniSTS:377822

REN53023 (e-PCR)
- UniSTS:377823

REN53024 (e-PCR)
- UniSTS:377824

REN53025 (e-PCR)
- UniSTS:377825

REN53028 (e-PCR)
- UniSTS:377828

REN53029 (e-PCR)
- UniSTS:377829

ECD10262 (e-PCR)
- UniSTS:291302

REN53031 (e-PCR)
- UniSTS:377831

REN53035 (e-PCR)
- UniSTS:377835

REN53036 (e-PCR)
- UniSTS:377836

ECD20290 (e-PCR)
- UniSTS:301293

REN53037 (e-PCR)
- UniSTS:377837

REN53040 (e-PCR)
- UniSTS:377840

REN53044 (e-PCR)
- UniSTS:377844

REN53046 (e-PCR)
- UniSTS:377846

REN53047 (e-PCR)
- UniSTS:377847

REN53050 (e-PCR)
- UniSTS:377850

ECD00742 (e-PCR)
- UniSTS:281851

REN53052 (e-PCR)
- UniSTS:377852

REN53053 (e-PCR)
- UniSTS:377853

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info	PubMed
enables protein binding	IEA Inferred from Electronic Annotation more info	PubMed
enables protein kinase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in muscle cell differentiation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in protein phosphorylation	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: striated muscle preferentially expressed protein kinase

Names: SPEG complex locus

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

NC_041765.1 Reference Mmul_10 Primary Assembly

Range

106865719..106924694

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_015111143.2 → XP_014966629.2 striated muscle preferentially expressed protein kinase isoform X9

Conserved Domains (5) summary

PTZ00449
Location:246 → 593

PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional

cd00063
Location:1282 → 1363

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam16650
Location:812 → 868

SPEG_u2; Unstructured region on SPEG complex protein

pfam07679
Location:722 → 811

I-set; Immunoglobulin I-set domain

cl21453
Location:1598 → 1691

PKc_like; Protein Kinases, catalytic domain
XM_015111136.2 → XP_014966622.2 striated muscle preferentially expressed protein kinase isoform X3

UniProtKB/TrEMBL

F7ERQ5

Related

ENSMMUP00000023576.4, ENSMMUT00000025199.4

Conserved Domains (5) summary

PHA03247
Location:1917 → 2263

PHA03247; large tegument protein UL36; Provisional

cd14108
Location:1537 → 1793

STKc_SPEG_rpt1; Catalytic kinase domain, first repeat, of Giant Serine/Threonine Kinase Striated muscle preferentially expressed protein kinase

cd14111
Location:2901 → 3157

STKc_SPEG_rpt2; Catalytic kinase domain, second repeat, of Giant Serine/Threonine Kinase Striated muscle preferentially expressed protein kinase

pfam16650
Location:753 → 807

SPEG_u2; Unstructured region on SPEG complex protein

pfam07679
Location:1424 → 1513

I-set; Immunoglobulin I-set domain
XM_015111135.2 → XP_014966621.2 striated muscle preferentially expressed protein kinase isoform X2

UniProtKB/TrEMBL

A0A5F7ZU89

Related

ENSMMUP00000069224.1, ENSMMUT00000108870.1

Conserved Domains (5) summary

PHA03247
Location:1919 → 2265

PHA03247; large tegument protein UL36; Provisional

cd14108
Location:1539 → 1795

STKc_SPEG_rpt1; Catalytic kinase domain, first repeat, of Giant Serine/Threonine Kinase Striated muscle preferentially expressed protein kinase

cd14111
Location:2903 → 3159

STKc_SPEG_rpt2; Catalytic kinase domain, second repeat, of Giant Serine/Threonine Kinase Striated muscle preferentially expressed protein kinase

pfam16650
Location:753 → 809

SPEG_u2; Unstructured region on SPEG complex protein

pfam07679
Location:663 → 752

I-set; Immunoglobulin I-set domain
XM_015111144.2 → XP_014966630.2 striated muscle preferentially expressed protein kinase isoform X10

UniProtKB/TrEMBL

F7ERP9

Conserved Domains (3) summary

PTZ00449
Location:246 → 593

PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional

pfam16650
Location:812 → 868

SPEG_u2; Unstructured region on SPEG complex protein

pfam07679
Location:722 → 811

I-set; Immunoglobulin I-set domain
XM_015111134.2 → XP_014966620.2 striated muscle preferentially expressed protein kinase isoform X1

UniProtKB/TrEMBL

A0A5F7ZU89

Conserved Domains (5) summary

PHA03247
Location:1978 → 2324

PHA03247; large tegument protein UL36; Provisional

cd14108
Location:1598 → 1854

STKc_SPEG_rpt1; Catalytic kinase domain, first repeat, of Giant Serine/Threonine Kinase Striated muscle preferentially expressed protein kinase

cd14111
Location:2962 → 3218

STKc_SPEG_rpt2; Catalytic kinase domain, second repeat, of Giant Serine/Threonine Kinase Striated muscle preferentially expressed protein kinase

pfam16650
Location:812 → 868

SPEG_u2; Unstructured region on SPEG complex protein

pfam07679
Location:722 → 811

I-set; Immunoglobulin I-set domain
XM_015111140.2 → XP_014966626.1 striated muscle preferentially expressed protein kinase isoform X7

Conserved Domains (6) summary

PHA03247
Location:1236 → 1602

PHA03247; large tegument protein UL36; Provisional

PHA03307
Location:1408 → 1831

PHA03307; transcriptional regulator ICP4; Provisional

cd14108
Location:876 → 1132

STKc_SPEG_rpt1; Catalytic kinase domain, first repeat, of Giant Serine/Threonine Kinase Striated muscle preferentially expressed protein kinase

cd14111
Location:2240 → 2496

STKc_SPEG_rpt2; Catalytic kinase domain, second repeat, of Giant Serine/Threonine Kinase Striated muscle preferentially expressed protein kinase

pfam16650
Location:90 → 146

SPEG_u2; Unstructured region on SPEG complex protein

pfam07679
Location:2 → 89

I-set; Immunoglobulin I-set domain
XM_015111137.2 → XP_014966623.1 striated muscle preferentially expressed protein kinase isoform X4

UniProtKB/TrEMBL

A0A5F7ZBH6

Conserved Domains (8) summary

cd00096
Location:1408 → 1477

Ig; Immunoglobulin domain

smart00408
Location:788 → 855

IGc2; Immunoglobulin C-2 Type

smart00220
Location:2872 → 3124

S_TKc; Serine/Threonine protein kinases, catalytic domain

pfam07679
Location:628 → 717

I-set; Immunoglobulin I-set domain

cd14108
Location:1504 → 1760

STKc_SPEG_rpt1; Catalytic kinase domain, first repeat, of Giant Serine/Threonine Kinase Striated muscle preferentially expressed protein kinase

cd14111
Location:2868 → 3124

STKc_SPEG_rpt2; Catalytic kinase domain, second repeat, of Giant Serine/Threonine Kinase Striated muscle preferentially expressed protein kinase

pfam16650
Location:718 → 774

SPEG_u2; Unstructured region on SPEG complex protein

cl11960
Location:645 → 717

Ig; Immunoglobulin domain
XM_015111138.2 → XP_014966624.1 striated muscle preferentially expressed protein kinase isoform X5

UniProtKB/TrEMBL

A0A5F7ZBH6

Related

ENSMMUP00000062525.1, ENSMMUT00000109921.1

Conserved Domains (8) summary

cd00096
Location:1349 → 1418

Ig; Immunoglobulin domain

smart00408
Location:729 → 796

IGc2; Immunoglobulin C-2 Type

smart00220
Location:2813 → 3065

S_TKc; Serine/Threonine protein kinases, catalytic domain

pfam07679
Location:569 → 658

I-set; Immunoglobulin I-set domain

cd14108
Location:1445 → 1701

STKc_SPEG_rpt1; Catalytic kinase domain, first repeat, of Giant Serine/Threonine Kinase Striated muscle preferentially expressed protein kinase

cd14111
Location:2809 → 3065

STKc_SPEG_rpt2; Catalytic kinase domain, second repeat, of Giant Serine/Threonine Kinase Striated muscle preferentially expressed protein kinase

pfam16650
Location:659 → 715

SPEG_u2; Unstructured region on SPEG complex protein

cl11960
Location:586 → 658

Ig; Immunoglobulin domain
XM_015111139.2 → XP_014966625.1 striated muscle preferentially expressed protein kinase isoform X6

UniProtKB/TrEMBL

A0A5F7ZU89

Conserved Domains (8) summary

cd00096
Location:1333 → 1402

Ig; Immunoglobulin domain

smart00408
Location:713 → 780

IGc2; Immunoglobulin C-2 Type

smart00220
Location:2797 → 3049

S_TKc; Serine/Threonine protein kinases, catalytic domain

pfam07679
Location:553 → 642

I-set; Immunoglobulin I-set domain

cd14108
Location:1429 → 1685

STKc_SPEG_rpt1; Catalytic kinase domain, first repeat, of Giant Serine/Threonine Kinase Striated muscle preferentially expressed protein kinase

cd14111
Location:2793 → 3049

STKc_SPEG_rpt2; Catalytic kinase domain, second repeat, of Giant Serine/Threonine Kinase Striated muscle preferentially expressed protein kinase

pfam16650
Location:643 → 699

SPEG_u2; Unstructured region on SPEG complex protein

cl11960
Location:570 → 642

Ig; Immunoglobulin domain
XM_028831140.1 → XP_028686973.1 striated muscle preferentially expressed protein kinase isoform X7

Conserved Domains (6) summary

PHA03247
Location:1236 → 1602

PHA03247; large tegument protein UL36; Provisional

PHA03307
Location:1408 → 1831

PHA03307; transcriptional regulator ICP4; Provisional

cd14108
Location:876 → 1132

STKc_SPEG_rpt1; Catalytic kinase domain, first repeat, of Giant Serine/Threonine Kinase Striated muscle preferentially expressed protein kinase

cd14111
Location:2240 → 2496

STKc_SPEG_rpt2; Catalytic kinase domain, second repeat, of Giant Serine/Threonine Kinase Striated muscle preferentially expressed protein kinase

pfam16650
Location:90 → 146

SPEG_u2; Unstructured region on SPEG complex protein

pfam07679
Location:2 → 89

I-set; Immunoglobulin I-set domain
XM_028831141.1 → XP_028686974.1 striated muscle preferentially expressed protein kinase isoform X8

Conserved Domains (5) summary

PHA03247
Location:1109 → 1475

PHA03247; large tegument protein UL36; Provisional

PHA03307
Location:1281 → 1704

PHA03307; transcriptional regulator ICP4; Provisional

cd14108
Location:749 → 1005

STKc_SPEG_rpt1; Catalytic kinase domain, first repeat, of Giant Serine/Threonine Kinase Striated muscle preferentially expressed protein kinase

cd14111
Location:2113 → 2369

STKc_SPEG_rpt2; Catalytic kinase domain, second repeat, of Giant Serine/Threonine Kinase Striated muscle preferentially expressed protein kinase

pfam07679
Location:636 → 725

I-set; Immunoglobulin I-set domain
XM_015111141.2 → XP_014966627.1 striated muscle preferentially expressed protein kinase isoform X8

Conserved Domains (5) summary

PHA03247
Location:1109 → 1475

PHA03247; large tegument protein UL36; Provisional

PHA03307
Location:1281 → 1704

PHA03307; transcriptional regulator ICP4; Provisional

cd14108
Location:749 → 1005

STKc_SPEG_rpt1; Catalytic kinase domain, first repeat, of Giant Serine/Threonine Kinase Striated muscle preferentially expressed protein kinase

cd14111
Location:2113 → 2369

STKc_SPEG_rpt2; Catalytic kinase domain, second repeat, of Giant Serine/Threonine Kinase Striated muscle preferentially expressed protein kinase

pfam07679
Location:636 → 725

I-set; Immunoglobulin I-set domain
XM_015111145.2 → XP_014966631.1 striated muscle preferentially expressed protein kinase isoform X11

UniProtKB/TrEMBL

A0A1D5R626

Conserved Domains (3) summary

smart00408
Location:33 → 100

IGc2; Immunoglobulin C-2 Type

pfam07679
Location:20 → 110

I-set; Immunoglobulin I-set domain

pfam16650
Location:1 → 19

SPEG_u2; Unstructured region on SPEG complex protein
XM_015111142.2 → XP_014966628.1 striated muscle preferentially expressed protein kinase isoform X8

Conserved Domains (5) summary

PHA03247
Location:1109 → 1475

PHA03247; large tegument protein UL36; Provisional

PHA03307
Location:1281 → 1704

PHA03307; transcriptional regulator ICP4; Provisional

cd14108
Location:749 → 1005

STKc_SPEG_rpt1; Catalytic kinase domain, first repeat, of Giant Serine/Threonine Kinase Striated muscle preferentially expressed protein kinase

cd14111
Location:2113 → 2369

STKc_SPEG_rpt2; Catalytic kinase domain, second repeat, of Giant Serine/Threonine Kinase Striated muscle preferentially expressed protein kinase

pfam07679
Location:636 → 725

I-set; Immunoglobulin I-set domain