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    CHRNA6 cholinergic receptor nicotinic alpha 6 subunit [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 705725, updated on 17-Aug-2024

    Summary

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    Official Symbol
    CHRNA6provided by VGNC
    Official Full Name
    cholinergic receptor nicotinic alpha 6 subunitprovided by VGNC
    Primary source
    VGNC:VGNC:70956
    See related
    Ensembl:ENSMMUG00000000163
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Also known as
    nica6
    Orthologs
    human mouse all
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    Genomic context

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    See CHRNA6 in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 8 NC_041761.1 (43369202..43438352, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 8 NC_027900.1 (41906382..41922498)

    Chromosome 8 - NC_041761.1Genomic Context describing neighboring genes Neighboring gene solute carrier family 20 member 2 Neighboring gene small integral membrane protein 19 Neighboring gene 60S ribosomal protein L7-like 1 Neighboring gene cholinergic receptor nicotinic beta 3 subunit Neighboring gene THAP domain containing 1 Neighboring gene ring finger protein 170

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables acetylcholine-gated monoatomic cation-selective channel activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables transmembrane signaling receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in chemical synaptic transmission IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in monoatomic ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in nervous system process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of membrane potential IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in neuron projection IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in postsynaptic membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in synapse IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    neuronal acetylcholine receptor subunit alpha-6
    Names
    cholinergic receptor, nicotinic, alpha 6 (neuronal)
    nicotinic acetylcholine receptor subunit alpha6

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041761.1 Reference Mmul_10 Primary Assembly

      Range
      43369202..43438352 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028852638.1 → XP_028708471.1  neuronal acetylcholine receptor subunit alpha-6 isoform X2

      UniProtKB/TrEMBL
      G7MZ81
      Conserved Domains (2) summary
      TIGR00860
      Location:1 → 405
      LIC; Cation transporter family protein
      cl28912
      Location:1 → 160
      LGIC_ECD; extracellular domain (ECD) of Cys-loop neurotransmitter-gated ion channels (also known as ligand-gated ion channel (LGIC))

    2. XM_001099152.4 → XP_001099152.1  neuronal acetylcholine receptor subunit alpha-6 isoform X1

      UniProtKB/TrEMBL
      A0A1D5QJI6, G7MZ81
      Related
      ENSMMUP00000048209.1, ENSMMUT00000061273.2
      Conserved Domains (3) summary
      TIGR00860
      Location:34 → 484
      LIC; Cation transporter family protein
      pfam02931
      Location:34 → 240
      Neur_chan_LBD; Neurotransmitter-gated ion-channel ligand binding domain
      pfam02932
      Location:247 → 483
      Neur_chan_memb; Neurotransmitter-gated ion-channel transmembrane region
    Nucleotide Protein
    Heading Accession and Version

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