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    HRAS HRas proto-oncogene, GTPase [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 698830, updated on 17-Aug-2024

    Summary

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    Official Symbol
    HRASprovided by VGNC
    Official Full Name
    HRas proto-oncogene, GTPaseprovided by VGNC
    Primary source
    VGNC:VGNC:73519
    Locus tag
    EGK_05817
    See related
    Ensembl:ENSMMUG00000021659
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See HRAS in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 14 NC_041767.1 (586076..589471, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 14 NC_027906.1 (374543..377905, complement)

    Chromosome 14 - NC_041767.1Genomic Context describing neighboring genes Neighboring gene phosphatidylserine synthase 2 Neighboring gene ribonuclease inhibitor Neighboring gene uncharacterized LOC106993152 Neighboring gene leucine rich repeat containing 56 Neighboring gene lamin tail domain containing 2 Neighboring gene Ras association domain family member 7

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables GDP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in Ras protein signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cellular senescence IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    GTPase HRas
    Names
    Transforming protein p21
    v-Ha-ras Harvey rat sarcoma viral oncogene homolog
    NP_001253350.1
    XP_014968664.1
    XP_028688383.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001266421.1 → NP_001253350.1  GTPase HRas

      See identical proteins and their annotated locations for NP_001253350.1

      Status: PROVISIONAL

      Source sequence(s)
      JU473732
      UniProtKB/TrEMBL
      A0A8J8XJP0, F7F5K9, G7NBC9
      Related
      ENSMMUP00000028522.1, ENSMMUT00000030480.3
      Conserved Domains (1) summary
      cd04138
      Location:3 → 164
      H_N_K_Ras_like; Ras GTPase family containing H-Ras,N-Ras and K-Ras4A/4B

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041767.1 Reference Mmul_10 Primary Assembly

      Range
      586076..589471 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015113178.2 → XP_014968664.1  GTPase HRas isoform X2

      UniProtKB/TrEMBL
      F7F5J9
      Related
      ENSMMUP00000028523.1, ENSMMUT00000030481.3
      Conserved Domains (1) summary
      cd04138
      Location:3 → 150
      H_N_K_Ras_like; Ras GTPase family containing H-Ras,N-Ras and K-Ras4A/4B

    2. XM_028832550.1 → XP_028688383.1  GTPase HRas isoform X1

      UniProtKB/TrEMBL
      A0A8J8XJP0, F7F5K9, G7NBC9
      Conserved Domains (1) summary
      cd04138
      Location:3 → 164
      H_N_K_Ras_like; Ras GTPase family containing H-Ras,N-Ras and K-Ras4A/4B

    RNA

    1. XR_001439298.2 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

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    Research Materials