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    DOK4 docking protein 4 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 704443, updated on 17-Aug-2024

    Summary

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    Official Symbol
    DOK4provided by VGNC
    Official Full Name
    docking protein 4provided by VGNC
    Primary source
    VGNC:VGNC:71867
    Locus tag
    EGK_12825
    See related
    Ensembl:ENSMMUG00000020475
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See DOK4 in Genome Data Viewer
    Location:
    chromosome: 20
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 20 NC_041773.1 (44705284..44719478, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 20 NC_027912.1 (41679082..41693232, complement)

    Chromosome 20 - NC_041773.1Genomic Context describing neighboring genes Neighboring gene C-C motif chemokine ligand 17 Neighboring gene cytokine induced apoptosis inhibitor 1 Neighboring gene coenzyme Q9 Neighboring gene RNA polymerase II subunit C Neighboring gene coiled-coil domain containing 102A Neighboring gene adhesion G protein-coupled receptor G5 Neighboring gene uncharacterized LOC114674295

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Process Evidence Code Pubs
    involved_in cell surface receptor protein tyrosine kinase signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of MAPK cascade IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    docking protein 4
    Names
    Downstream of tyrosine kinase 4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001266155.1 → NP_001253084.1  docking protein 4

      See identical proteins and their annotated locations for NP_001253084.1

      Status: PROVISIONAL

      Source sequence(s)
      JV043859
      UniProtKB/TrEMBL
      A0A5F8AF63, A0A8J8XDI8, F6VK00, G7NPU8
      Related
      ENSMMUP00000063537.1, ENSMMUT00000100382.1
      Conserved Domains (2) summary
      cd13164
      Location:133 → 235
      PTB_DOK4_DOK5_DOK6; Downstream of tyrosine kinase 4, 5, and 6 proteins phosphotyrosine-binding domain (PTBi)
      cd14678
      Location:9 → 113
      PH_DOK4_DOK5_DOK6; Pleckstrin homology (PH) domain of Downstream of tyrosine kinase 4, 5, and 6 proteins

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041773.1 Reference Mmul_10 Primary Assembly

      Range
      44705284..44719478 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015126176.2 → XP_014981662.1  docking protein 4 isoform X2

      UniProtKB/TrEMBL
      A0A5F8AF63, A0A8J8XDI8, F6VK00, G7NPU8
      Related
      ENSMMUP00000026971.2, ENSMMUT00000028822.4
      Conserved Domains (2) summary
      cd13164
      Location:133 → 235
      PTB_DOK4_DOK5_DOK6; Downstream of tyrosine kinase 4, 5, and 6 proteins phosphotyrosine-binding domain (PTBi)
      cd14678
      Location:9 → 113
      PH_DOK4_DOK5_DOK6; Pleckstrin homology (PH) domain of Downstream of tyrosine kinase 4, 5, and 6 proteins

    2. XM_028840469.1 → XP_028696302.1  docking protein 4 isoform X1

      UniProtKB/TrEMBL
      A0A5F8AF63
      Conserved Domains (2) summary
      cd13164
      Location:133 → 235
      PTB_DOK4_DOK5_DOK6; Downstream of tyrosine kinase 4, 5, and 6 proteins phosphotyrosine-binding domain (PTBi)
      cd14678
      Location:9 → 113
      PH_DOK4_DOK5_DOK6; Pleckstrin homology (PH) domain of Downstream of tyrosine kinase 4, 5, and 6 proteins

    3. XM_028840471.1 → XP_028696304.1  docking protein 4 isoform X1

      UniProtKB/TrEMBL
      A0A5F8AF63
      Conserved Domains (2) summary
      cd13164
      Location:133 → 235
      PTB_DOK4_DOK5_DOK6; Downstream of tyrosine kinase 4, 5, and 6 proteins phosphotyrosine-binding domain (PTBi)
      cd14678
      Location:9 → 113
      PH_DOK4_DOK5_DOK6; Pleckstrin homology (PH) domain of Downstream of tyrosine kinase 4, 5, and 6 proteins

    4. XM_028840470.1 → XP_028696303.1  docking protein 4 isoform X1

      UniProtKB/TrEMBL
      A0A5F8AF63
      Conserved Domains (2) summary
      cd13164
      Location:133 → 235
      PTB_DOK4_DOK5_DOK6; Downstream of tyrosine kinase 4, 5, and 6 proteins phosphotyrosine-binding domain (PTBi)
      cd14678
      Location:9 → 113
      PH_DOK4_DOK5_DOK6; Pleckstrin homology (PH) domain of Downstream of tyrosine kinase 4, 5, and 6 proteins

    5. XM_028840472.1 → XP_028696305.1  docking protein 4 isoform X3

      UniProtKB/TrEMBL
      A0A5F8AF63
      Conserved Domains (2) summary
      cd13164
      Location:133 → 235
      PTB_DOK4_DOK5_DOK6; Downstream of tyrosine kinase 4, 5, and 6 proteins phosphotyrosine-binding domain (PTBi)
      cd14678
      Location:9 → 113
      PH_DOK4_DOK5_DOK6; Pleckstrin homology (PH) domain of Downstream of tyrosine kinase 4, 5, and 6 proteins
    Nucleotide Protein
    Heading Accession and Version

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