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    NCF4 neutrophil cytosolic factor 4 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 695612, updated on 17-Aug-2024

    Summary

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    Official Symbol
    NCF4provided by VGNC
    Official Full Name
    neutrophil cytosolic factor 4provided by VGNC
    Primary source
    VGNC:VGNC:75141
    See related
    Ensembl:ENSMMUG00000008160
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See NCF4 in Genome Data Viewer
    Location:
    chromosome: 10
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 10 NC_041763.1 (14692626..14711565, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 10 NC_027902.1 (78764579..78783430)

    Chromosome 10 - NC_041763.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA U13 Neighboring gene colony stimulating factor 2 receptor subunit beta Neighboring gene uncharacterized LOC114670360 Neighboring gene parvalbumin Neighboring gene intraflagellar transport 27

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables phosphatidylinositol binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables superoxide-generating NADPH oxidase activator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in phagocytosis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in respiratory burst IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in superoxide anion generation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of NADPH oxidase complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    neutrophil cytosol factor 4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041763.1 Reference Mmul_10 Primary Assembly

      Range
      14692626..14711565 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015150254.2 → XP_015005740.1  neutrophil cytosol factor 4 isoform X1

      UniProtKB/TrEMBL
      A0A5F7Z836
      Related
      ENSMMUP00000061653.1, ENSMMUT00000100341.1
      Conserved Domains (3) summary
      cd06882
      Location:19 → 141
      PX_p40phox; The phosphoinositide binding Phox Homology domain of the p40phox subunit of NADPH oxidase
      cd11869
      Location:174 → 227
      SH3_p40phox; Src Homology 3 domain of the p40phox subunit of NADPH oxidase
      cl02720
      Location:238 → 258
      PB1; The PB1 domain is a modular domain mediating specific protein-protein interactions which play a role in many critical cell processes, such as osteoclastogenesis, angiogenesis, early cardiovascular development, and cell polarity. A canonical PB1-PB1 ...

    2. XM_015150255.2 → XP_015005741.1  neutrophil cytosol factor 4 isoform X2

      UniProtKB/TrEMBL
      F7HE13, H9YWW4
      Related
      ENSMMUP00000051437.1, ENSMMUT00000068457.2
      Conserved Domains (3) summary
      cd06399
      Location:238 → 329
      PB1_P40; The PB1 domain is essential part of the p40 adaptor protein which plays an important role in activating phagocyte NADPH oxidase during phagocytosis. The PB1 domain is a modular domain mediating specific protein-protein interaction which play a role in ...
      cd06882
      Location:19 → 141
      PX_p40phox; The phosphoinositide binding Phox Homology domain of the p40phox subunit of NADPH oxidase
      cd11869
      Location:174 → 227
      SH3_p40phox; Src Homology 3 domain of the p40phox subunit of NADPH oxidase
    Nucleotide Protein
    Heading Accession and Version

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