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    PDPR pyruvate dehydrogenase phosphatase regulatory subunit [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 709861, updated on 17-Aug-2024

    Summary

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    Official Symbol
    PDPRprovided by VGNC
    Official Full Name
    pyruvate dehydrogenase phosphatase regulatory subunitprovided by VGNC
    Primary source
    VGNC:VGNC:75897
    Locus tag
    EGK_12992
    See related
    Ensembl:ENSMMUG00000023147
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See PDPR in Genome Data Viewer
    Location:
    chromosome: 20
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 20 NC_041773.1 (61324548..61375941, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 20 NC_027912.1 (58630412..58677378, complement)

    Chromosome 20 - NC_041773.1Genomic Context describing neighboring genes Neighboring gene heterogeneous nuclear ribonucleoproteins C1/C2-like Neighboring gene transfer RNA glycine (anticodon GCC) Neighboring gene C-type lectin domain family 18, member A Neighboring gene golgi glycoprotein 1 Neighboring gene 10 kDa heat shock protein, mitochondrial pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in mitochondrial matrix IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial
    Names
    Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial
    XP_014982101.1
    XP_028697441.1
    XP_028697442.1
    XP_028697443.1
    XP_028697444.1
    XP_028697446.1
    XP_028697447.1
    XP_028697448.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041773.1 Reference Mmul_10 Primary Assembly

      Range
      61324548..61375941 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028841609.1 → XP_028697442.1  pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial isoform X3

      UniProtKB/TrEMBL
      A0A5F7ZKJ3, I2CXA2
      Related
      ENSMMUP00000066136.1, ENSMMUT00000104224.1
      Conserved Domains (4) summary
      COG0665
      Location:38 → 425
      DadA; Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism]
      pfam01571
      Location:462 → 683
      GCV_T; Aminomethyltransferase folate-binding domain
      pfam08669
      Location:724 → 790
      GCV_T_C; Glycine cleavage T-protein C-terminal barrel domain
      pfam16350
      Location:404 → 459
      FAO_M; FAD dependent oxidoreductase central domain

    2. XM_028841614.1 → XP_028697447.1  pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial isoform X5

      Conserved Domains (4) summary
      COG0665
      Location:10 → 154
      DadA; Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism]
      pfam01571
      Location:191 → 464
      GCV_T; Aminomethyltransferase folate-binding domain
      pfam08669
      Location:514 → 580
      GCV_T_C; Glycine cleavage T-protein C-terminal barrel domain
      pfam16350
      Location:133 → 188
      FAO_M; FAD dependent oxidoreductase central domain

    3. XM_028841608.1 → XP_028697441.1  pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial isoform X1

      UniProtKB/TrEMBL
      I2CXA2
      Conserved Domains (4) summary
      COG0665
      Location:3 → 390
      DadA; Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism]
      pfam01571
      Location:427 → 700
      GCV_T; Aminomethyltransferase folate-binding domain
      pfam08669
      Location:712 → 816
      GCV_T_C; Glycine cleavage T-protein C-terminal barrel domain
      pfam16350
      Location:375 → 423
      FAO_M; FAD dependent oxidoreductase central domain

    4. XM_028841613.1 → XP_028697446.1  pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial isoform X5

      Conserved Domains (4) summary
      COG0665
      Location:10 → 154
      DadA; Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism]
      pfam01571
      Location:191 → 464
      GCV_T; Aminomethyltransferase folate-binding domain
      pfam08669
      Location:514 → 580
      GCV_T_C; Glycine cleavage T-protein C-terminal barrel domain
      pfam16350
      Location:133 → 188
      FAO_M; FAD dependent oxidoreductase central domain

    5. XM_028841615.1 → XP_028697448.1  pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial isoform X6

      Conserved Domains (3) summary
      pfam01571
      Location:61 → 334
      GCV_T; Aminomethyltransferase folate-binding domain
      pfam08669
      Location:384 → 450
      GCV_T_C; Glycine cleavage T-protein C-terminal barrel domain
      pfam16350
      Location:3 → 58
      FAO_M; FAD dependent oxidoreductase central domain

    6. XM_028841610.1 → XP_028697443.1  pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial isoform X4

      UniProtKB/TrEMBL
      I2CXA2
      Conserved Domains (4) summary
      COG0665
      Location:1 → 326
      DadA; Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism]
      pfam01571
      Location:363 → 636
      GCV_T; Aminomethyltransferase folate-binding domain
      pfam08669
      Location:648 → 752
      GCV_T_C; Glycine cleavage T-protein C-terminal barrel domain
      pfam16350
      Location:311 → 359
      FAO_M; FAD dependent oxidoreductase central domain

    7. XM_015126615.2 → XP_014982101.1  pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial isoform X2

      UniProtKB/TrEMBL
      A0A663DCF7, A0A8J8XKT6, F6RY22, F7FHQ0, G7NR12, I2CXA2
      Related
      ENSMMUP00000030474.4, ENSMMUT00000032566.4
      Conserved Domains (4) summary
      COG0665
      Location:38 → 425
      DadA; Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism]
      pfam01571
      Location:462 → 735
      GCV_T; Aminomethyltransferase folate-binding domain
      pfam08669
      Location:785 → 851
      GCV_T_C; Glycine cleavage T-protein C-terminal barrel domain
      pfam16350
      Location:404 → 459
      FAO_M; FAD dependent oxidoreductase central domain

    8. XM_028841611.1 → XP_028697444.1  pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial isoform X4

      UniProtKB/TrEMBL
      I2CXA2
      Conserved Domains (4) summary
      COG0665
      Location:1 → 326
      DadA; Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism]
      pfam01571
      Location:363 → 636
      GCV_T; Aminomethyltransferase folate-binding domain
      pfam08669
      Location:648 → 752
      GCV_T_C; Glycine cleavage T-protein C-terminal barrel domain
      pfam16350
      Location:311 → 359
      FAO_M; FAD dependent oxidoreductase central domain

    RNA

    1. XR_003725642.1 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

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