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    LTK leukocyte receptor tyrosine kinase [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 710624, updated on 17-Aug-2024

    Summary

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    Official Symbol
    LTKprovided by VGNC
    Official Full Name
    leukocyte receptor tyrosine kinaseprovided by VGNC
    Primary source
    VGNC:VGNC:84372
    See related
    Ensembl:ENSMMUG00000008170
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See LTK in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 7 NC_041760.1 (17966884..17978302, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 7 NC_027899.1 (17876110..17887119, complement)

    Chromosome 7 - NC_041760.1Genomic Context describing neighboring genes Neighboring gene RTF1 homolog, Paf1/RNA polymerase II complex component Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC106999152 Neighboring gene inositol-trisphosphate 3-kinase A Neighboring gene RNA polymerase II associated protein 1 Neighboring gene TYRO3 protein tyrosine kinase

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables transmembrane receptor protein tyrosine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell surface receptor protein tyrosine kinase signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in multicellular organism development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of cell population proliferation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of neuron differentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of receptor complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    leukocyte tyrosine kinase receptor
    Names
    leukocyte tyrosine kinase
    XP_014997472.1
    XP_014997473.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041760.1 Reference Mmul_10 Primary Assembly

      Range
      17966884..17978302 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015141987.2 → XP_014997473.1  leukocyte tyrosine kinase receptor isoform X2

      Conserved Domains (2) summary
      pfam07714
      Location:415 → 647
      Pkinase_Tyr; Protein tyrosine kinase
      cl21453
      Location:414 → 649
      PKc_like; Protein Kinases, catalytic domain

    2. XM_015141986.2 → XP_014997472.1  leukocyte tyrosine kinase receptor isoform X1

      UniProtKB/TrEMBL
      F7HBY2
      Related
      ENSMMUP00000010695.4, ENSMMUT00000011411.4
      Conserved Domains (2) summary
      cd05036
      Location:503 → 779
      PTKc_ALK_LTK; Catalytic domain of the Protein Tyrosine Kinases, Anaplastic Lymphoma Kinase and Leukocyte Tyrosine Kinase
      pfam07714
      Location:510 → 777
      Pkinase_Tyr; Protein tyrosine kinase
    Nucleotide Protein
    Heading Accession and Version

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