U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    PGPEP1 pyroglutamyl-peptidase I [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 720200, updated on 17-Aug-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    PGPEP1provided by VGNC
    Official Full Name
    pyroglutamyl-peptidase Iprovided by VGNC
    Primary source
    VGNC:VGNC:75797
    Locus tag
    EGK_10328
    See related
    Ensembl:ENSMMUG00000004406
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See PGPEP1 in Genome Data Viewer
    Location:
    chromosome: 19
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 19 NC_041772.1 (17883500..17912673)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 19 NC_027911.1 (18364514..18387602)

    Chromosome 19 - NC_041772.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC114674223 Neighboring gene LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated Neighboring gene growth differentiation factor 15 Neighboring gene leucine rich repeat containing 25

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables pyroglutamyl-peptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    pyroglutamyl-peptidase 1
    NP_001247617.1
    XP_014978792.1
    XP_014978793.1
    XP_014978795.1
    XP_028694382.1
    XP_028694383.1
    XP_028694384.1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001260688.1 → NP_001247617.1  pyroglutamyl-peptidase 1

      See identical proteins and their annotated locations for NP_001247617.1

      Status: PROVISIONAL

      Source sequence(s)
      JU473664
      UniProtKB/TrEMBL
      A0A5F8APU9, A0A8J8Y1J7, G7NNE0, H9Z3F2
      Related
      ENSMMUP00000061666.1, ENSMMUT00000097338.1
      Conserved Domains (1) summary
      cd00501
      Location:6 → 199
      Peptidase_C15; Pyroglutamyl peptidase (PGP) type I, also known as pyrrolidone carboxyl peptidase (pcp) type I: Enzymes responsible for cleaving pyroglutamate (pGlu) from the N-terminal end of specialized proteins. The N-terminal pGlu protects these proteins from ...

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041772.1 Reference Mmul_10 Primary Assembly

      Range
      17883500..17912673
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028838551.1 → XP_028694384.1  pyroglutamyl-peptidase 1 isoform X4

      Conserved Domains (1) summary
      cd00501
      Location:6 → 146
      Peptidase_C15; Pyroglutamyl peptidase (PGP) type I, also known as pyrrolidone carboxyl peptidase (pcp) type I: Enzymes responsible for cleaving pyroglutamate (pGlu) from the N-terminal end of specialized proteins. The N-terminal pGlu protects these proteins from ...

    2. XM_015123306.2 → XP_014978792.1  pyroglutamyl-peptidase 1 isoform X3

      UniProtKB/TrEMBL
      F7GUB6
      Related
      ENSMMUP00000005884.2, ENSMMUT00000006254.3
      Conserved Domains (1) summary
      cl00237
      Location:6 → 92
      Peptidase_C15; Pyroglutamyl peptidase (PGP) type I, also known as pyrrolidone carboxyl peptidase (pcp) type I: Enzymes responsible for cleaving pyroglutamate (pGlu) from the N-terminal end of specialized proteins. The N-terminal pGlu protects these proteins from ...

    3. XM_015123309.2 → XP_014978795.1  pyroglutamyl-peptidase 1 isoform X5

      Conserved Domains (1) summary
      cd00501
      Location:6 → 146
      Peptidase_C15; Pyroglutamyl peptidase (PGP) type I, also known as pyrrolidone carboxyl peptidase (pcp) type I: Enzymes responsible for cleaving pyroglutamate (pGlu) from the N-terminal end of specialized proteins. The N-terminal pGlu protects these proteins from ...

    4. XM_028838549.1 → XP_028694382.1  pyroglutamyl-peptidase 1 isoform X2

      Conserved Domains (1) summary
      cl00237
      Location:84 → 166
      Peptidase_C15; Pyroglutamyl peptidase (PGP) type I, also known as pyrrolidone carboxyl peptidase (pcp) type I: Enzymes responsible for cleaving pyroglutamate (pGlu) from the N-terminal end of specialized proteins. The N-terminal pGlu protects these proteins from ...

    5. XM_015123307.2 → XP_014978793.1  pyroglutamyl-peptidase 1 isoform X1

      UniProtKB/TrEMBL
      H9FBD3
      Conserved Domains (1) summary
      cl00237
      Location:1 → 122
      Peptidase_C15; Pyroglutamyl peptidase (PGP) type I, also known as pyrrolidone carboxyl peptidase (pcp) type I: Enzymes responsible for cleaving pyroglutamate (pGlu) from the N-terminal end of specialized proteins. The N-terminal pGlu protects these proteins from ...

    6. XM_028838550.1 → XP_028694383.1  pyroglutamyl-peptidase 1 isoform X1

      UniProtKB/TrEMBL
      H9FBD3
      Conserved Domains (1) summary
      cl00237
      Location:1 → 122
      Peptidase_C15; Pyroglutamyl peptidase (PGP) type I, also known as pyrrolidone carboxyl peptidase (pcp) type I: Enzymes responsible for cleaving pyroglutamate (pGlu) from the N-terminal end of specialized proteins. The N-terminal pGlu protects these proteins from ...
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.