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    LOC695267 supervillin [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 695267, updated on 9-Nov-2023

    Summary

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    Gene symbol
    LOC695267
    Gene description
    supervillin
    See related
    Ensembl:ENSMMUG00000001374
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Also known as
    SVIL
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    Genomic context

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    See LOC695267 in Genome Data Viewer
    Location:
    chromosome: 9
    Exon count:
    45
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 9 NC_041762.1 (30368854..30640190, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 9 NC_027901.1 (29585815..29857181, complement)

    Chromosome 9 - NC_041762.1Genomic Context describing neighboring genes Neighboring gene lysozyme-like protein 1 Neighboring gene uncharacterized LOC107000088 Neighboring gene small nucleolar RNA SNORD115 Neighboring gene microRNA mir-604 Neighboring gene microRNA mir-938 Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC114670110 Neighboring gene uncharacterized LOC114669910 Neighboring gene junctional cadherin 5 associated

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables actin filament binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables phosphatidylinositol-4,5-bisphosphate binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in actin filament severing IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in actin polymerization or depolymerization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in barbed-end actin filament capping IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cytoskeleton organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in actin cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    supervillin

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041762.1 Reference Mmul_10 Primary Assembly

      Range
      30368854..30640190 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028826127.1 → XP_028681960.1  supervillin isoform X1

      UniProtKB/TrEMBL
      A0A5F7ZI57, A0A5F8AP93
      Conserved Domains (6) summary
      smart00153
      Location:2205 → 2240
      VHP; Villin headpiece domain
      cd11280
      Location:1589 → 1689
      gelsolin_like; Tandemly repeated domains found in gelsolin, severin, villin, and related proteins
      cd11288
      Location:1905 → 2010
      gelsolin_S5_like; Gelsolin sub-domain 5-like domain found in gelsolin, severin, villin, and related proteins
      cd11289
      Location:1468 → 1564
      gelsolin_S2_like; Gelsolin sub-domain 2-like domain found in gelsolin, severin, villin, and related proteins
      cd11293
      Location:1772 → 1885
      gelsolin_S4_like; Gelsolin sub-domain 4-like domain found in gelsolin, severin, villin, and related proteins
      cl15697
      Location:2027 → 2149
      ADF_gelsolin; Actin depolymerization factor/cofilin- and gelsolin-like domains

    2. XM_015146702.2 → XP_015002188.2  supervillin isoform X1

      UniProtKB/TrEMBL
      A0A5F7ZI57, A0A5F8AP93
      Conserved Domains (6) summary
      smart00153
      Location:2205 → 2240
      VHP; Villin headpiece domain
      cd11280
      Location:1589 → 1689
      gelsolin_like; Tandemly repeated domains found in gelsolin, severin, villin, and related proteins
      cd11288
      Location:1905 → 2010
      gelsolin_S5_like; Gelsolin sub-domain 5-like domain found in gelsolin, severin, villin, and related proteins
      cd11289
      Location:1468 → 1564
      gelsolin_S2_like; Gelsolin sub-domain 2-like domain found in gelsolin, severin, villin, and related proteins
      cd11293
      Location:1772 → 1885
      gelsolin_S4_like; Gelsolin sub-domain 4-like domain found in gelsolin, severin, villin, and related proteins
      cl15697
      Location:2027 → 2149
      ADF_gelsolin; Actin depolymerization factor/cofilin- and gelsolin-like domains

    3. XM_015146699.2 → XP_015002185.2  supervillin isoform X1

      UniProtKB/TrEMBL
      A0A5F7ZI57, A0A5F8AP93
      Conserved Domains (6) summary
      smart00153
      Location:2205 → 2240
      VHP; Villin headpiece domain
      cd11280
      Location:1589 → 1689
      gelsolin_like; Tandemly repeated domains found in gelsolin, severin, villin, and related proteins
      cd11288
      Location:1905 → 2010
      gelsolin_S5_like; Gelsolin sub-domain 5-like domain found in gelsolin, severin, villin, and related proteins
      cd11289
      Location:1468 → 1564
      gelsolin_S2_like; Gelsolin sub-domain 2-like domain found in gelsolin, severin, villin, and related proteins
      cd11293
      Location:1772 → 1885
      gelsolin_S4_like; Gelsolin sub-domain 4-like domain found in gelsolin, severin, villin, and related proteins
      cl15697
      Location:2027 → 2149
      ADF_gelsolin; Actin depolymerization factor/cofilin- and gelsolin-like domains

    4. XM_015146704.2 → XP_015002190.2  supervillin isoform X1

      UniProtKB/TrEMBL
      A0A5F7ZI57, A0A5F8AP93
      Related
      ENSMMUP00000065287.1, ENSMMUT00000105461.1
      Conserved Domains (6) summary
      smart00153
      Location:2205 → 2240
      VHP; Villin headpiece domain
      cd11280
      Location:1589 → 1689
      gelsolin_like; Tandemly repeated domains found in gelsolin, severin, villin, and related proteins
      cd11288
      Location:1905 → 2010
      gelsolin_S5_like; Gelsolin sub-domain 5-like domain found in gelsolin, severin, villin, and related proteins
      cd11289
      Location:1468 → 1564
      gelsolin_S2_like; Gelsolin sub-domain 2-like domain found in gelsolin, severin, villin, and related proteins
      cd11293
      Location:1772 → 1885
      gelsolin_S4_like; Gelsolin sub-domain 4-like domain found in gelsolin, severin, villin, and related proteins
      cl15697
      Location:2027 → 2149
      ADF_gelsolin; Actin depolymerization factor/cofilin- and gelsolin-like domains

    5. XM_015146715.2 → XP_015002201.2  supervillin isoform X13

      UniProtKB/TrEMBL
      I2CVF2
      Conserved Domains (6) summary
      smart00153
      Location:1739 → 1774
      VHP; Villin headpiece domain
      cd11280
      Location:1123 → 1223
      gelsolin_like; Tandemly repeated domains found in gelsolin, severin, villin, and related proteins
      cd11288
      Location:1439 → 1544
      gelsolin_S5_like; Gelsolin sub-domain 5-like domain found in gelsolin, severin, villin, and related proteins
      cd11289
      Location:1002 → 1098
      gelsolin_S2_like; Gelsolin sub-domain 2-like domain found in gelsolin, severin, villin, and related proteins
      cd11293
      Location:1306 → 1419
      gelsolin_S4_like; Gelsolin sub-domain 4-like domain found in gelsolin, severin, villin, and related proteins
      cl15697
      Location:1561 → 1683
      ADF_gelsolin; Actin depolymerization factor/cofilin- and gelsolin-like domains

    6. XM_015146714.2 → XP_015002200.2  supervillin isoform X11

      UniProtKB/TrEMBL
      I2CVF2
      Conserved Domains (6) summary
      smart00153
      Location:1781 → 1816
      VHP; Villin headpiece domain
      cd11280
      Location:1165 → 1265
      gelsolin_like; Tandemly repeated domains found in gelsolin, severin, villin, and related proteins
      cd11288
      Location:1481 → 1586
      gelsolin_S5_like; Gelsolin sub-domain 5-like domain found in gelsolin, severin, villin, and related proteins
      cd11289
      Location:1044 → 1140
      gelsolin_S2_like; Gelsolin sub-domain 2-like domain found in gelsolin, severin, villin, and related proteins
      cd11293
      Location:1348 → 1461
      gelsolin_S4_like; Gelsolin sub-domain 4-like domain found in gelsolin, severin, villin, and related proteins
      cl15697
      Location:1603 → 1725
      ADF_gelsolin; Actin depolymerization factor/cofilin- and gelsolin-like domains

    7. XM_028826130.1 → XP_028681963.1  supervillin isoform X12

      UniProtKB/TrEMBL
      I2CVF2
      Conserved Domains (6) summary
      smart00153
      Location:1771 → 1806
      VHP; Villin headpiece domain
      cd11280
      Location:1155 → 1255
      gelsolin_like; Tandemly repeated domains found in gelsolin, severin, villin, and related proteins
      cd11288
      Location:1471 → 1576
      gelsolin_S5_like; Gelsolin sub-domain 5-like domain found in gelsolin, severin, villin, and related proteins
      cd11289
      Location:1034 → 1130
      gelsolin_S2_like; Gelsolin sub-domain 2-like domain found in gelsolin, severin, villin, and related proteins
      cd11293
      Location:1338 → 1451
      gelsolin_S4_like; Gelsolin sub-domain 4-like domain found in gelsolin, severin, villin, and related proteins
      cl15697
      Location:1593 → 1715
      ADF_gelsolin; Actin depolymerization factor/cofilin- and gelsolin-like domains

    8. XM_015146713.2 → XP_015002199.2  supervillin isoform X10

      UniProtKB/TrEMBL
      F7D0W1
      Related
      ENSMMUP00000001841.4, ENSMMUT00000001954.4
      Conserved Domains (6) summary
      smart00153
      Location:1813 → 1848
      VHP; Villin headpiece domain
      cd11280
      Location:1197 → 1297
      gelsolin_like; Tandemly repeated domains found in gelsolin, severin, villin, and related proteins
      cd11288
      Location:1513 → 1618
      gelsolin_S5_like; Gelsolin sub-domain 5-like domain found in gelsolin, severin, villin, and related proteins
      cd11289
      Location:1076 → 1172
      gelsolin_S2_like; Gelsolin sub-domain 2-like domain found in gelsolin, severin, villin, and related proteins
      cd11293
      Location:1380 → 1493
      gelsolin_S4_like; Gelsolin sub-domain 4-like domain found in gelsolin, severin, villin, and related proteins
      cl15697
      Location:1635 → 1757
      ADF_gelsolin; Actin depolymerization factor/cofilin- and gelsolin-like domains

    9. XM_015146711.2 → XP_015002197.2  supervillin isoform X9

      UniProtKB/TrEMBL
      F7D0W1
      Conserved Domains (6) summary
      smart00153
      Location:1840 → 1875
      VHP; Villin headpiece domain
      cd11280
      Location:1224 → 1324
      gelsolin_like; Tandemly repeated domains found in gelsolin, severin, villin, and related proteins
      cd11288
      Location:1540 → 1645
      gelsolin_S5_like; Gelsolin sub-domain 5-like domain found in gelsolin, severin, villin, and related proteins
      cd11289
      Location:1103 → 1199
      gelsolin_S2_like; Gelsolin sub-domain 2-like domain found in gelsolin, severin, villin, and related proteins
      cd11293
      Location:1407 → 1520
      gelsolin_S4_like; Gelsolin sub-domain 4-like domain found in gelsolin, severin, villin, and related proteins
      cl15697
      Location:1662 → 1784
      ADF_gelsolin; Actin depolymerization factor/cofilin- and gelsolin-like domains

    10. XM_028826128.1 → XP_028681961.1  supervillin isoform X8

      UniProtKB/TrEMBL
      I2CVF2
      Conserved Domains (6) summary
      smart00153
      Location:1855 → 1890
      VHP; Villin headpiece domain
      cd11280
      Location:1239 → 1339
      gelsolin_like; Tandemly repeated domains found in gelsolin, severin, villin, and related proteins
      cd11288
      Location:1555 → 1660
      gelsolin_S5_like; Gelsolin sub-domain 5-like domain found in gelsolin, severin, villin, and related proteins
      cd11289
      Location:1118 → 1214
      gelsolin_S2_like; Gelsolin sub-domain 2-like domain found in gelsolin, severin, villin, and related proteins
      cd11293
      Location:1422 → 1535
      gelsolin_S4_like; Gelsolin sub-domain 4-like domain found in gelsolin, severin, villin, and related proteins
      cl15697
      Location:1677 → 1799
      ADF_gelsolin; Actin depolymerization factor/cofilin- and gelsolin-like domains

    11. XM_015146710.2 → XP_015002196.2  supervillin isoform X7

      UniProtKB/TrEMBL
      A0A1D5RBR1
      Related
      ENSMMUP00000057752.2, ENSMMUT00000075862.2
      Conserved Domains (6) summary
      smart00153
      Location:1897 → 1932
      VHP; Villin headpiece domain
      cd11280
      Location:1281 → 1381
      gelsolin_like; Tandemly repeated domains found in gelsolin, severin, villin, and related proteins
      cd11288
      Location:1597 → 1702
      gelsolin_S5_like; Gelsolin sub-domain 5-like domain found in gelsolin, severin, villin, and related proteins
      cd11289
      Location:1160 → 1256
      gelsolin_S2_like; Gelsolin sub-domain 2-like domain found in gelsolin, severin, villin, and related proteins
      cd11293
      Location:1464 → 1577
      gelsolin_S4_like; Gelsolin sub-domain 4-like domain found in gelsolin, severin, villin, and related proteins
      cl15697
      Location:1719 → 1841
      ADF_gelsolin; Actin depolymerization factor/cofilin- and gelsolin-like domains

    12. XM_015146708.2 → XP_015002194.2  supervillin isoform X5

      UniProtKB/TrEMBL
      A0A5F8AP93
      Related
      ENSMMUP00000062275.1, ENSMMUT00000087764.1
      Conserved Domains (6) summary
      smart00153
      Location:2148 → 2183
      VHP; Villin headpiece domain
      cd11280
      Location:1532 → 1632
      gelsolin_like; Tandemly repeated domains found in gelsolin, severin, villin, and related proteins
      cd11288
      Location:1848 → 1953
      gelsolin_S5_like; Gelsolin sub-domain 5-like domain found in gelsolin, severin, villin, and related proteins
      cd11289
      Location:1411 → 1507
      gelsolin_S2_like; Gelsolin sub-domain 2-like domain found in gelsolin, severin, villin, and related proteins
      cd11293
      Location:1715 → 1828
      gelsolin_S4_like; Gelsolin sub-domain 4-like domain found in gelsolin, severin, villin, and related proteins
      cl15697
      Location:1970 → 2092
      ADF_gelsolin; Actin depolymerization factor/cofilin- and gelsolin-like domains

    13. XM_015146709.2 → XP_015002195.2  supervillin isoform X6

      UniProtKB/TrEMBL
      A0A5F8AP93
      Conserved Domains (6) summary
      smart00153
      Location:2131 → 2166
      VHP; Villin headpiece domain
      cd11280
      Location:1515 → 1615
      gelsolin_like; Tandemly repeated domains found in gelsolin, severin, villin, and related proteins
      cd11288
      Location:1831 → 1936
      gelsolin_S5_like; Gelsolin sub-domain 5-like domain found in gelsolin, severin, villin, and related proteins
      cd11289
      Location:1394 → 1490
      gelsolin_S2_like; Gelsolin sub-domain 2-like domain found in gelsolin, severin, villin, and related proteins
      cd11293
      Location:1698 → 1811
      gelsolin_S4_like; Gelsolin sub-domain 4-like domain found in gelsolin, severin, villin, and related proteins
      cl15697
      Location:1953 → 2075
      ADF_gelsolin; Actin depolymerization factor/cofilin- and gelsolin-like domains

    14. XM_015146706.2 → XP_015002192.2  supervillin isoform X3

      UniProtKB/TrEMBL
      A0A5F8AP93
      Related
      ENSMMUP00000001836.4, ENSMMUT00000001949.4
      Conserved Domains (6) summary
      smart00153
      Location:2173 → 2208
      VHP; Villin headpiece domain
      cd11280
      Location:1557 → 1657
      gelsolin_like; Tandemly repeated domains found in gelsolin, severin, villin, and related proteins
      cd11288
      Location:1873 → 1978
      gelsolin_S5_like; Gelsolin sub-domain 5-like domain found in gelsolin, severin, villin, and related proteins
      cd11289
      Location:1436 → 1532
      gelsolin_S2_like; Gelsolin sub-domain 2-like domain found in gelsolin, severin, villin, and related proteins
      cd11293
      Location:1740 → 1853
      gelsolin_S4_like; Gelsolin sub-domain 4-like domain found in gelsolin, severin, villin, and related proteins
      cl15697
      Location:1995 → 2117
      ADF_gelsolin; Actin depolymerization factor/cofilin- and gelsolin-like domains

    15. XM_015146707.2 → XP_015002193.2  supervillin isoform X4

      UniProtKB/TrEMBL
      A0A5F8AP93
      Related
      ENSMMUP00000001839.4, ENSMMUT00000001952.4
      Conserved Domains (6) summary
      smart00153
      Location:2163 → 2198
      VHP; Villin headpiece domain
      cd11280
      Location:1547 → 1647
      gelsolin_like; Tandemly repeated domains found in gelsolin, severin, villin, and related proteins
      cd11288
      Location:1863 → 1968
      gelsolin_S5_like; Gelsolin sub-domain 5-like domain found in gelsolin, severin, villin, and related proteins
      cd11289
      Location:1426 → 1522
      gelsolin_S2_like; Gelsolin sub-domain 2-like domain found in gelsolin, severin, villin, and related proteins
      cd11293
      Location:1730 → 1843
      gelsolin_S4_like; Gelsolin sub-domain 4-like domain found in gelsolin, severin, villin, and related proteins
      cl15697
      Location:1985 → 2107
      ADF_gelsolin; Actin depolymerization factor/cofilin- and gelsolin-like domains

    16. XM_015146705.2 → XP_015002191.2  supervillin isoform X2

      UniProtKB/TrEMBL
      A0A5F8AP93
      Related
      ENSMMUP00000056228.2, ENSMMUT00000074188.2
      Conserved Domains (6) summary
      smart00153
      Location:2179 → 2214
      VHP; Villin headpiece domain
      cd11280
      Location:1563 → 1663
      gelsolin_like; Tandemly repeated domains found in gelsolin, severin, villin, and related proteins
      cd11288
      Location:1879 → 1984
      gelsolin_S5_like; Gelsolin sub-domain 5-like domain found in gelsolin, severin, villin, and related proteins
      cd11289
      Location:1442 → 1538
      gelsolin_S2_like; Gelsolin sub-domain 2-like domain found in gelsolin, severin, villin, and related proteins
      cd11293
      Location:1746 → 1859
      gelsolin_S4_like; Gelsolin sub-domain 4-like domain found in gelsolin, severin, villin, and related proteins
      cl15697
      Location:2001 → 2123
      ADF_gelsolin; Actin depolymerization factor/cofilin- and gelsolin-like domains

    17. XM_015146698.2 → XP_015002184.2  supervillin isoform X1

      UniProtKB/TrEMBL
      A0A5F7ZI57, A0A5F8AP93
      Conserved Domains (6) summary
      smart00153
      Location:2205 → 2240
      VHP; Villin headpiece domain
      cd11280
      Location:1589 → 1689
      gelsolin_like; Tandemly repeated domains found in gelsolin, severin, villin, and related proteins
      cd11288
      Location:1905 → 2010
      gelsolin_S5_like; Gelsolin sub-domain 5-like domain found in gelsolin, severin, villin, and related proteins
      cd11289
      Location:1468 → 1564
      gelsolin_S2_like; Gelsolin sub-domain 2-like domain found in gelsolin, severin, villin, and related proteins
      cd11293
      Location:1772 → 1885
      gelsolin_S4_like; Gelsolin sub-domain 4-like domain found in gelsolin, severin, villin, and related proteins
      cl15697
      Location:2027 → 2149
      ADF_gelsolin; Actin depolymerization factor/cofilin- and gelsolin-like domains
    Nucleotide Protein
    Heading Accession and Version

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