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    TNNT2 troponin T2, cardiac type [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 709882, updated on 17-Aug-2024

    Summary

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    Official Symbol
    TNNT2provided by VGNC
    Official Full Name
    troponin T2, cardiac typeprovided by VGNC
    Primary source
    VGNC:VGNC:106524
    See related
    Ensembl:ENSMMUG00000056199
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See TNNT2 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 1 NC_041754.1 (58779791..58798498, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 1 NC_027893.1 (165390416..165409065)

    Chromosome 1 - NC_041754.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC114677710 Neighboring gene plakophilin 1 Neighboring gene ladinin 1 Neighboring gene uncharacterized LOC114679682 Neighboring gene troponin I1, slow skeletal type

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables tropomyosin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables troponin C binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables troponin I binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cardiac muscle contraction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of muscle contraction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in sarcomere organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of troponin complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    troponin T, cardiac muscle
    Names
    troponin T type 2 (cardiac)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001247991.2 → NP_001234920.2  troponin T, cardiac muscle

      Status: VALIDATED

      Source sequence(s)
      QNVO02000005
      Related
      ENSMMUP00000017761.4, ENSMMUT00000018964.4
      Conserved Domains (1) summary
      pfam00992
      Location:97 → 232
      Troponin

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041754.1 Reference Mmul_10 Primary Assembly

      Range
      58779791..58798498 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028843872.1 → XP_028699705.1  troponin T, cardiac muscle isoform X14

      UniProtKB/TrEMBL
      F6ZDL9
      Conserved Domains (1) summary
      pfam00992
      Location:92 → 229
      Troponin

    2. XM_028843857.1 → XP_028699690.1  troponin T, cardiac muscle isoform X10

      Conserved Domains (1) summary
      pfam00992
      Location:97 → 232
      Troponin

    3. XM_028843834.1 → XP_028699667.1  troponin T, cardiac muscle isoform X5

      Conserved Domains (1) summary
      pfam00992
      Location:107 → 242
      Troponin

    4. XM_028843833.1 → XP_028699666.1  troponin T, cardiac muscle isoform X4

      Conserved Domains (1) summary
      pfam00992
      Location:107 → 244
      Troponin

    5. XM_015118840.2 → XP_014974326.2  troponin T, cardiac muscle isoform X2

      Conserved Domains (1) summary
      pfam00992
      Location:106 → 244
      Troponin

    6. XM_028843850.1 → XP_028699683.1  troponin T, cardiac muscle isoform X8

      Conserved Domains (1) summary
      pfam00992
      Location:96 → 234
      Troponin

    7. XM_028843829.1 → XP_028699662.1  troponin T, cardiac muscle isoform X3

      Conserved Domains (1) summary
      pfam00992
      Location:106 → 244
      Troponin

    8. XM_028843815.1 → XP_028699648.1  troponin T, cardiac muscle isoform X1

      UniProtKB/TrEMBL
      F6ZDK2
      Related
      ENSMMUP00000017763.4, ENSMMUT00000018966.4
      Conserved Domains (1) summary
      pfam00992
      Location:107 → 245
      Troponin

    9. XM_028843866.1 → XP_028699699.1  troponin T, cardiac muscle isoform X13

      UniProtKB/TrEMBL
      F6ZDL9
      Conserved Domains (1) summary
      pfam00992
      Location:91 → 229
      Troponin

    10. XM_028843841.1 → XP_028699674.1  troponin T, cardiac muscle isoform X7

      Conserved Domains (1) summary
      pfam00992
      Location:96 → 234
      Troponin

    11. XM_028843861.1 → XP_028699694.1  troponin T, cardiac muscle isoform X12

      UniProtKB/TrEMBL
      F6ZDL9
      Conserved Domains (1) summary
      pfam00992
      Location:92 → 230
      Troponin

    12. XM_028843837.1 → XP_028699670.1  troponin T, cardiac muscle isoform X6

      Conserved Domains (1) summary
      pfam00992
      Location:97 → 235
      Troponin

    13. XM_028843883.1 → XP_028699716.1  troponin T, cardiac muscle isoform X16

      UniProtKB/TrEMBL
      F6ZDL9
      Conserved Domains (1) summary
      pfam00992
      Location:75 → 213
      Troponin

    14. XM_028843874.1 → XP_028699707.1  troponin T, cardiac muscle isoform X15

      UniProtKB/TrEMBL
      F6ZDL9
      Conserved Domains (1) summary
      pfam00992
      Location:76 → 214
      Troponin

    15. XM_028843858.1 → XP_028699691.1  troponin T, cardiac muscle isoform X11

      UniProtKB/TrEMBL
      F6ZDL9
      Conserved Domains (1) summary
      pfam00992
      Location:93 → 231
      Troponin

    16. XM_028843852.1 → XP_028699685.1  troponin T, cardiac muscle isoform X9

      UniProtKB/TrEMBL
      F6ZDL9
      Conserved Domains (1) summary
      pfam00992
      Location:94 → 232
      Troponin

    17. XM_028843824.1 → XP_028699657.1  troponin T, cardiac muscle isoform X2

      Conserved Domains (1) summary
      pfam00992
      Location:106 → 244
      Troponin

    18. XM_028843816.1 → XP_028699649.1  troponin T, cardiac muscle isoform X1

      UniProtKB/TrEMBL
      F6ZDK2
      Conserved Domains (1) summary
      pfam00992
      Location:107 → 245
      Troponin

    19. XM_028843840.1 → XP_028699673.1  troponin T, cardiac muscle isoform X6

      Conserved Domains (1) summary
      pfam00992
      Location:97 → 235
      Troponin

    20. XM_028843869.1 → XP_028699702.1  troponin T, cardiac muscle isoform X13

      UniProtKB/TrEMBL
      F6ZDL9
      Conserved Domains (1) summary
      pfam00992
      Location:91 → 229
      Troponin

    21. XM_028843865.1 → XP_028699698.1  troponin T, cardiac muscle isoform X12

      UniProtKB/TrEMBL
      F6ZDL9
      Conserved Domains (1) summary
      pfam00992
      Location:92 → 230
      Troponin

    22. XM_028843886.1 → XP_028699719.1  troponin T, cardiac muscle isoform X16

      UniProtKB/TrEMBL
      F6ZDL9
      Conserved Domains (1) summary
      pfam00992
      Location:75 → 213
      Troponin

    23. XM_028843854.1 → XP_028699687.1  troponin T, cardiac muscle isoform X9

      UniProtKB/TrEMBL
      F6ZDL9
      Conserved Domains (1) summary
      pfam00992
      Location:94 → 232
      Troponin

    24. XM_015118854.2 → XP_014974340.2  troponin T, cardiac muscle isoform X15

      UniProtKB/TrEMBL
      F6ZDL9
      Conserved Domains (1) summary
      pfam00992
      Location:76 → 214
      Troponin

    25. XM_028843826.1 → XP_028699659.1  troponin T, cardiac muscle isoform X2

      Conserved Domains (1) summary
      pfam00992
      Location:106 → 244
      Troponin

    26. XM_028843846.1 → XP_028699679.1  troponin T, cardiac muscle isoform X7

      Conserved Domains (1) summary
      pfam00992
      Location:96 → 234
      Troponin

    27. XM_028843876.1 → XP_028699709.1  troponin T, cardiac muscle isoform X15

      UniProtKB/TrEMBL
      F6ZDL9
      Conserved Domains (1) summary
      pfam00992
      Location:76 → 214
      Troponin
    Nucleotide Protein
    Heading Accession and Version

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