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    FBXL4 F-box and leucine rich repeat protein 4 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 693683, updated on 17-Aug-2024

    Summary

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    Official Symbol
    FBXL4provided by VGNC
    Official Full Name
    F-box and leucine rich repeat protein 4provided by VGNC
    Primary source
    VGNC:VGNC:81069
    Locus tag
    EGK_15185
    See related
    Ensembl:ENSMMUG00000001659
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See FBXL4 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 4 NC_041757.1 (74338590..74417738)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 4 NC_027896.1 (97378767..97460435, complement)

    Chromosome 4 - NC_041757.1Genomic Context describing neighboring genes Neighboring gene 60S ribosomal protein L3 pseudogene Neighboring gene uncharacterized LOC114677393 Neighboring gene POU class 3 homeobox 2 Neighboring gene uncharacterized LOC114677537

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of SCF ubiquitin ligase complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    F-box/LRR-repeat protein 4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001266033.1 → NP_001252962.1  F-box/LRR-repeat protein 4

      See identical proteins and their annotated locations for NP_001252962.1

      Status: PROVISIONAL

      Source sequence(s)
      JU475125
      UniProtKB/TrEMBL
      A0A5F7ZDJ7, A0A5F7ZND2, A0A8J8Y9J6, G7MPZ0
      Related
      ENSMMUP00000065437.1, ENSMMUT00000079904.1
      Conserved Domains (3) summary
      cd09293
      Location:394 → 601
      AMN1; Antagonist of mitotic exit network protein 1
      sd00034
      Location:403 → 427
      LRR_AMN1; leucine-rich repeat [structural motif]
      pfam12937
      Location:280 → 326
      F-box-like; F-box-like

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041757.1 Reference Mmul_10 Primary Assembly

      Range
      74338590..74417738
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015136948.2 → XP_014992434.1  F-box/LRR-repeat protein 4 isoform X1

      UniProtKB/TrEMBL
      A0A5F7ZDJ7, A0A5F7ZND2, A0A8J8Y9J6, G7MPZ0
      Related
      ENSMMUP00000079845.1, ENSMMUT00000103553.1
      Conserved Domains (3) summary
      cd09293
      Location:394 → 601
      AMN1; Antagonist of mitotic exit network protein 1
      sd00034
      Location:403 → 427
      LRR_AMN1; leucine-rich repeat [structural motif]
      pfam12937
      Location:280 → 326
      F-box-like; F-box-like

    2. XM_015136949.2 → XP_014992435.1  F-box/LRR-repeat protein 4 isoform X1

      UniProtKB/TrEMBL
      A0A5F7ZDJ7, A0A5F7ZND2, A0A8J8Y9J6, G7MPZ0
      Related
      ENSMMUP00000063694.1, ENSMMUT00000094728.1
      Conserved Domains (3) summary
      cd09293
      Location:394 → 601
      AMN1; Antagonist of mitotic exit network protein 1
      sd00034
      Location:403 → 427
      LRR_AMN1; leucine-rich repeat [structural motif]
      pfam12937
      Location:280 → 326
      F-box-like; F-box-like
    Nucleotide Protein
    Heading Accession and Version

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