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    SPG7 SPG7 matrix AAA peptidase subunit, paraplegin [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 699488, updated on 17-Aug-2024

    Summary

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    Official Symbol
    SPG7provided by VGNC
    Official Full Name
    SPG7 matrix AAA peptidase subunit, parapleginprovided by VGNC
    Primary source
    VGNC:VGNC:99592
    See related
    Ensembl:ENSMMUG00000017920
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See SPG7 in Genome Data Viewer
    Location:
    chromosome: 20
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 20 NC_041773.1 (76545630..76599872)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 20 NC_027912.1 (74368627..74426119)

    Chromosome 20 - NC_041773.1Genomic Context describing neighboring genes Neighboring gene ankyrin repeat domain containing 11 Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC114674357 Neighboring gene uncharacterized LOC114674358 Neighboring gene small nucleolar RNA MBII-202 Neighboring gene ribosomal protein L13 Neighboring gene copine 7

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ATP-dependent peptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables metalloendopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in mitochondrial protein processing IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein-containing complex assembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of m-AAA complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    paraplegin
    Names
    SPG7, paraplegin matrix AAA peptidase subunit

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041773.1 Reference Mmul_10 Primary Assembly

      Range
      76545630..76599872
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028840888.1 → XP_028696721.1  paraplegin isoform X2

      UniProtKB/TrEMBL
      A0A5F7Z916
      Conserved Domains (2) summary
      TIGR01241
      Location:264 → 727
      FtsH_fam; ATP-dependent metalloprotease FtsH
      pfam06480
      Location:144 → 241
      FtsH_ext; FtsH Extracellular

    2. XM_028840887.1 → XP_028696720.1  paraplegin isoform X1

      UniProtKB/TrEMBL
      A0A1D5Q0N0, A0A5F7Z916
      Related
      ENSMMUP00000041592.2, ENSMMUT00000077569.2
      Conserved Domains (2) summary
      TIGR01241
      Location:264 → 747
      FtsH_fam; ATP-dependent metalloprotease FtsH
      pfam06480
      Location:144 → 241
      FtsH_ext; FtsH Extracellular

    3. XM_028840891.1 → XP_028696724.1  paraplegin isoform X5

      UniProtKB/TrEMBL
      A0A1D5Q9S8, A0A5F7Z916
      Related
      ENSMMUP00000044796.2, ENSMMUT00000056617.2
      Conserved Domains (2) summary
      TIGR01241
      Location:264 → 634
      FtsH_fam; ATP-dependent metalloprotease FtsH
      pfam06480
      Location:144 → 241
      FtsH_ext; FtsH Extracellular

    4. XM_028840889.1 → XP_028696722.1  paraplegin isoform X3

      UniProtKB/TrEMBL
      A0A5F7Z916
      Conserved Domains (2) summary
      TIGR01241
      Location:219 → 666
      FtsH_fam; ATP-dependent metalloprotease FtsH
      pfam06480
      Location:144 → 190
      FtsH_ext; FtsH Extracellular

    5. XM_028840890.1 → XP_028696723.1  paraplegin isoform X4

      UniProtKB/TrEMBL
      A0A5F7Z916
      Conserved Domains (2) summary
      TIGR01241
      Location:264 → 645
      FtsH_fam; ATP-dependent metalloprotease FtsH
      pfam06480
      Location:144 → 241
      FtsH_ext; FtsH Extracellular

    6. XM_028840892.1 → XP_028696725.1  paraplegin isoform X6

      Conserved Domains (2) summary
      TIGR01241
      Location:264 → 593
      FtsH_fam; ATP-dependent metalloprotease FtsH
      pfam06480
      Location:144 → 241
      FtsH_ext; FtsH Extracellular
    Nucleotide Protein
    Heading Accession and Version

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