DR1 down-regulator of transcription 1 [Macaca mulatta (Rhesus monkey)] - Gene

Summary

Gene symbol: DR1
Gene description: down-regulator of transcription 1
Locus tag: EGK_00979
See related: Ensembl:ENSMMUG00000015922
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Macaca mulatta
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 1

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
103	current	Mmul_10 (GCF_003339765.1)	1	NC_041754.1 (130779420..130795911, complement)
102	previous assembly	Mmul_8.0.1 (GCF_000772875.2)	1	NC_027893.1 (94017968..94034783)

Chromosome 1 - NC_041754.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables TBP-class protein binding	IEA Inferred from Electronic Annotation more info	PubMed
enables core promoter sequence-specific DNA binding	IEA Inferred from Electronic Annotation more info	PubMed
enables general transcription initiation factor activity	IEA Inferred from Electronic Annotation more info	PubMed
enables protein heterodimerization activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in RNA polymerase II preinitiation complex assembly	IEA Inferred from Electronic Annotation more info	PubMed
involved_in chromatin remodeling	IEA Inferred from Electronic Annotation more info	PubMed
involved_in negative regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
part_of negative cofactor 2 complex	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: protein Dr1

Names: down-regulator of transcription 1, TBP-binding (negative cofactor 2)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001257839.1 → NP_001244768.1 protein Dr1

See identical proteins and their annotated locations for NP_001244768.1

Status: PROVISIONAL

Source sequence(s)

JU333253

UniProtKB/TrEMBL

A0A8J8YJE8, F7C9G1, G7MI33

Related

ENSMMUP00000076749.1, ENSMMUT00000107881.1

Conserved Domains (1) summary

cl23735
Location:7 → 130

H4; Histone H4, one of the four histones, along with H2A, H2B and H3, which forms the eukaryotic nucleosome core; along with H3, it plays a central role in nucleosome formation; histones bind to DNA and wrap the genetic material into "beads on a string" in ...