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    NLRP1 NLR family pyrin domain containing 1 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 721648, updated on 14-Nov-2024

    Summary

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    Official Symbol
    NLRP1provided by VGNC
    Official Full Name
    NLR family pyrin domain containing 1provided by VGNC
    Primary source
    VGNC:VGNC:99189
    See related
    Ensembl:ENSMMUG00000030453
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See NLRP1 in Genome Data Viewer
    Location:
    chromosome: 16
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 16 NC_041769.1 (5314800..5370299, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 16 NC_027908.1 (5495311..5550666, complement)

    Chromosome 16 - NC_041769.1Genomic Context describing neighboring genes Neighboring gene U7 small nuclear RNA Neighboring gene uncharacterized LOC712349 Neighboring gene MIS12 kinetochore complex component Neighboring gene protein NipSnap homolog 1 pseudogene Neighboring gene WSC domain containing 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification of oocyte-selective NLRP genes in rhesus macaque monkeys (Macaca mulatta). McDaniel P, et al. Mol Reprod Dev, 2009 Feb. PMID 18509866
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in inflammatory response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in innate immune response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of apoptotic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of canonical inflammasome complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    NACHT, LRR and PYD domains-containing protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001114349.1 → NP_001107821.1  NACHT, LRR and PYD domains-containing protein 1

      See identical proteins and their annotated locations for NP_001107821.1

      Status: PROVISIONAL

      Source sequence(s)
      EU344968
      UniProtKB/TrEMBL
      B0FPF1, H9H2X9
      Related
      ENSMMUP00000004772.4, ENSMMUT00000005064.4
      Conserved Domains (7) summary
      smart00382
      Location:331 → 417
      AAA; ATPases associated with a variety of cellular activities
      cd00116
      Location:814 → 982
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      cd08330
      Location:1382 → 1462
      CARD_ASC_NALP1; Caspase activation and recruitment domain found in Human ASC, NALP1, and similar proteins
      sd00034
      Location:814 → 842
      LRR_AMN1; leucine-rich repeat [structural motif]
      pfam05729
      Location:332 → 501
      NACHT; NACHT domain
      pfam13553
      Location:1102 → 1356
      FIIND; Function to find
      cl14633
      Location:24 → 88
      DD; Death Domain Superfamily of protein-protein interaction domains

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041769.1 Reference Mmul_10 Primary Assembly

      Range
      5314800..5370299 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

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    Research Materials