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    RFWD3 ring finger and WD repeat domain 3 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 710227, updated on 17-Aug-2024

    Summary

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    Official Symbol
    RFWD3provided by VGNC
    Official Full Name
    ring finger and WD repeat domain 3provided by VGNC
    Primary source
    VGNC:VGNC:76820
    See related
    Ensembl:ENSMMUG00000008375
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See RFWD3 in Genome Data Viewer
    Location:
    chromosome: 20
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 20 NC_041773.1 (61582763..61630769, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 20 NC_027912.1 (58882772..58934459, complement)

    Chromosome 20 - NC_041773.1Genomic Context describing neighboring genes Neighboring gene golgi glycoprotein 1 Neighboring gene 10 kDa heat shock protein, mitochondrial pseudogene Neighboring gene lamina-associated polypeptide 2 Neighboring gene mixed lineage kinase domain like pseudokinase Neighboring gene fatty acid 2-hydroxylase

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ubiquitin protein ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in double-strand break repair via homologous recombination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in interstrand cross-link repair IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in site of double-strand break IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    E3 ubiquitin-protein ligase RFWD3
    XP_014982103.1
    XP_014982105.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041773.1 Reference Mmul_10 Primary Assembly

      Range
      61582763..61630769 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015126617.2 → XP_014982103.1  E3 ubiquitin-protein ligase RFWD3

      UniProtKB/TrEMBL
      F7HMP1, G7NR14, H9ZAQ5, I0FKH5
      Related
      ENSMMUP00000010980.3, ENSMMUT00000011709.4
      Conserved Domains (3) summary
      sd00039
      Location:500 → 537
      7WD40; WD40 repeat [structural motif]
      cd16450
      Location:283 → 331
      mRING-C3HGC3_RFWD3; Modified RING finger, C3HGC3-type, found in RING finger and WD repeat domain-containing protein 3 (RFWD3) and similar proteins
      cl29593
      Location:496 → 762
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    2. XM_015126619.2 → XP_014982105.1  E3 ubiquitin-protein ligase RFWD3

      UniProtKB/TrEMBL
      F7HMP1, G7NR14, H9ZAQ5, I0FKH5
      Conserved Domains (3) summary
      sd00039
      Location:500 → 537
      7WD40; WD40 repeat [structural motif]
      cd16450
      Location:283 → 331
      mRING-C3HGC3_RFWD3; Modified RING finger, C3HGC3-type, found in RING finger and WD repeat domain-containing protein 3 (RFWD3) and similar proteins
      cl29593
      Location:496 → 762
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    Nucleotide Protein
    Heading Accession and Version

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