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    ACAN aggrecan [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 698498, updated on 17-Aug-2024

    Summary

    Official Symbol
    ACANprovided by VGNC
    Official Full Name
    aggrecanprovided by VGNC
    Primary source
    VGNC:VGNC:69556
    See related
    Ensembl:ENSMMUG00000000554
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Also known as
    AGC1
    Orthologs
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    Genomic context

    See ACAN in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 7 NC_041760.1 (67588642..67628335)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 7 NC_027899.1 (66828872..66868855)

    Chromosome 7 - NC_041760.1Genomic Context describing neighboring genes Neighboring gene microRNA mir-7-2 Neighboring gene apoptosis enhancing nuclease Neighboring gene interferon stimulated exonuclease gene 20 Neighboring gene hyaluronan and proteoglycan link protein 3 Neighboring gene milk fat globule EGF and factor V/VIII domain containing

    Genomic regions, transcripts, and products

    General gene information

    Markers

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables hyaluronic acid binding IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in cell adhesion IEA
    Inferred from Electronic Annotation
    more info
    PubMed 

    General protein information

    Preferred Names
    aggrecan core protein
    Names
    aggrecan core protein-like

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041760.1 Reference Mmul_10 Primary Assembly

      Range
      67588642..67628335
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015142968.2XP_014998454.2  aggrecan core protein isoform X1

      UniProtKB/TrEMBL
      F7C5R9
      Conserved Domains (8) summary
      cd05900
      Location:43154
      Ig_Aggrecan; Immunoglobulin (Ig)-like domain of the chondroitin sulfate proteoglycan core protein (CSPG), aggrecan
      cd00033
      Location:21832239
      CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
      cd03588
      Location:20562179
      CLECT_CSPGs; C-type lectin-like domain (CTLD) of the type found in chondroitin sulfate proteoglycan core proteins
      PRK15387
      Location:11491330
      PRK15387; E3 ubiquitin-protein ligase SspH2; Provisional
      PHA03307
      Location:725975
      PHA03307; transcriptional regulator ICP4; Provisional
      cd00054
      Location:20192049
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      cd03517
      Location:153247
      Link_domain_CSPGs_modules_1_3; this extracellular link domain is found in the first and third link modules of the chondroitin sulfate proteoglycan core protein (CSPG) aggrecan. In addition, it is found in the first link module of three other CSPGs: versican, neurocan, and brevican. ...
      cd03520
      Location:254349
      Link_domain_CSPGs_modules_2_4; this link domain is found in the second and fourth link modules of the chondroitin sulfate proteoglycan core protein (CSPG) aggrecan and, in the second link module of three other CSPGs: versican, neurocan, and brevican. The link domain is a hyaluronan ...
    2. XM_015142970.2XP_014998456.2  aggrecan core protein isoform X2

      UniProtKB/TrEMBL
      F6ZXF7, F7C5R9
      Related
      ENSMMUP00000000745.4, ENSMMUT00000000805.4
      Conserved Domains (7) summary
      cd05900
      Location:43154
      Ig_Aggrecan; Immunoglobulin (Ig)-like domain of the chondroitin sulfate proteoglycan core protein (CSPG), aggrecan
      cd00033
      Location:21452201
      CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
      cd03588
      Location:20182141
      CLECT_CSPGs; C-type lectin-like domain (CTLD) of the type found in chondroitin sulfate proteoglycan core proteins
      PRK15387
      Location:11491330
      PRK15387; E3 ubiquitin-protein ligase SspH2; Provisional
      PHA03307
      Location:725975
      PHA03307; transcriptional regulator ICP4; Provisional
      cd03517
      Location:153247
      Link_domain_CSPGs_modules_1_3; this extracellular link domain is found in the first and third link modules of the chondroitin sulfate proteoglycan core protein (CSPG) aggrecan. In addition, it is found in the first link module of three other CSPGs: versican, neurocan, and brevican. ...
      cd03520
      Location:254349
      Link_domain_CSPGs_modules_2_4; this link domain is found in the second and fourth link modules of the chondroitin sulfate proteoglycan core protein (CSPG) aggrecan and, in the second link module of three other CSPGs: versican, neurocan, and brevican. The link domain is a hyaluronan ...