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    CDC42BPA CDC42 binding protein kinase alpha [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 697811, updated on 17-Aug-2024

    Summary

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    Official Symbol
    CDC42BPAprovided by VGNC
    Official Full Name
    CDC42 binding protein kinase alphaprovided by VGNC
    Primary source
    VGNC:VGNC:70799
    See related
    Ensembl:ENSMMUG00000008638
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See CDC42BPA in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    45
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 1 NC_041754.1 (84563713..84892135, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 1 NC_027893.1 (137966694..138322213, complement)

    Chromosome 1 - NC_041754.1Genomic Context describing neighboring genes Neighboring gene presenilin 2 Neighboring gene uncharacterized LOC106993264 Neighboring gene coenzyme Q8A Neighboring gene 40S ribosomal protein S18 pseudogene Neighboring gene nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in actomyosin structure organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in peptidyl-threonine phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in actomyosin IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    serine/threonine-protein kinase MRCK alpha
    XP_028682030.1
    XP_028682035.1
    XP_028682037.1
    XP_028682044.1
    XP_028682048.1
    XP_028682055.1
    XP_028682063.1
    XP_028682072.1
    XP_028682077.1
    XP_028682080.1
    XP_028682081.1
    XP_028682082.1
    XP_028682087.1
    XP_028682091.1
    XP_028682103.1
    XP_028682105.1
    XP_028682110.1
    XP_028682115.1
    XP_028682121.1
    XP_028682123.1
    XP_028682128.1
    XP_028682133.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041754.1 Reference Mmul_10 Primary Assembly

      Range
      84563713..84892135 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028826288.1 → XP_028682121.1  serine/threonine-protein kinase MRCK alpha isoform X19

      UniProtKB/TrEMBL
      G7MEE0
      Conserved Domains (7) summary
      smart00285
      Location:1538 → 1572
      PBD; P21-Rho-binding domain
      COG0419
      Location:442 → 944
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      cd00029
      Location:980 → 1029
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
      cd01243
      Location:1039 → 1173
      PH_MRCK; MRCK (myotonic dystrophy-related Cdc42-binding kinase) pleckstrin homology (PH) domain
      cd05623
      Location:4 → 412
      STKc_MRCK_alpha; Catalytic domain of the Serine/Threonine Kinase, DMPK-related cell division control protein 42 binding kinase (MRCK) alpha
      pfam00780
      Location:1199 → 1463
      CNH; CNH domain
      pfam15796
      Location:530 → 608
      KELK; KELK-motif containing domain of MRCK Ser/Thr protein kinase

    2. XM_028826272.1 → XP_028682105.1  serine/threonine-protein kinase MRCK alpha isoform X16

      UniProtKB/TrEMBL
      G7MEE0
      Conserved Domains (7) summary
      smart00285
      Location:1571 → 1605
      PBD; P21-Rho-binding domain
      COG0419
      Location:432 → 941
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      cd00029
      Location:1013 → 1062
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
      cd01243
      Location:1072 → 1206
      PH_MRCK; MRCK (myotonic dystrophy-related Cdc42-binding kinase) pleckstrin homology (PH) domain
      cd05623
      Location:4 → 412
      STKc_MRCK_alpha; Catalytic domain of the Serine/Threonine Kinase, DMPK-related cell division control protein 42 binding kinase (MRCK) alpha
      pfam00780
      Location:1232 → 1496
      CNH; CNH domain
      pfam15796
      Location:530 → 608
      KELK; KELK-motif containing domain of MRCK Ser/Thr protein kinase

    3. XM_028826258.1 → XP_028682091.1  serine/threonine-protein kinase MRCK alpha isoform X14

      UniProtKB/TrEMBL
      F7F892
      Conserved Domains (7) summary
      smart00285
      Location:1593 → 1627
      PBD; P21-Rho-binding domain
      COG0419
      Location:432 → 941
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      cd00029
      Location:1035 → 1084
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
      cd01243
      Location:1094 → 1228
      PH_MRCK; MRCK (myotonic dystrophy-related Cdc42-binding kinase) pleckstrin homology (PH) domain
      cd05623
      Location:4 → 412
      STKc_MRCK_alpha; Catalytic domain of the Serine/Threonine Kinase, DMPK-related cell division control protein 42 binding kinase (MRCK) alpha
      pfam00780
      Location:1254 → 1518
      CNH; CNH domain
      pfam15796
      Location:530 → 608
      KELK; KELK-motif containing domain of MRCK Ser/Thr protein kinase

    4. XM_028826244.1 → XP_028682077.1  serine/threonine-protein kinase MRCK alpha isoform X9

      UniProtKB/TrEMBL
      F7F892, F7GKD9
      Related
      ENSMMUP00000038447.3, ENSMMUT00000045419.3
      Conserved Domains (7) summary
      smart00285
      Location:1622 → 1656
      PBD; P21-Rho-binding domain
      COG0419
      Location:432 → 941
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      cd00029
      Location:1064 → 1113
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
      cd01243
      Location:1123 → 1257
      PH_MRCK; MRCK (myotonic dystrophy-related Cdc42-binding kinase) pleckstrin homology (PH) domain
      cd05623
      Location:4 → 412
      STKc_MRCK_alpha; Catalytic domain of the Serine/Threonine Kinase, DMPK-related cell division control protein 42 binding kinase (MRCK) alpha
      pfam00780
      Location:1283 → 1547
      CNH; CNH domain
      pfam15796
      Location:530 → 608
      KELK; KELK-motif containing domain of MRCK Ser/Thr protein kinase

    5. XM_028826295.1 → XP_028682128.1  serine/threonine-protein kinase MRCK alpha isoform X21

      UniProtKB/TrEMBL
      G7MEE0, H9ESV4
      Conserved Domains (7) summary
      pfam08826
      Location:800 → 860
      DMPK_coil; DMPK coiled coil domain like
      smart00285
      Location:1477 → 1511
      PBD; P21-Rho-binding domain
      COG0419
      Location:442 → 860
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      cd00029
      Location:919 → 968
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
      cd01243
      Location:978 → 1112
      PH_MRCK; MRCK (myotonic dystrophy-related Cdc42-binding kinase) pleckstrin homology (PH) domain
      cd05623
      Location:4 → 412
      STKc_MRCK_alpha; Catalytic domain of the Serine/Threonine Kinase, DMPK-related cell division control protein 42 binding kinase (MRCK) alpha
      pfam00780
      Location:1138 → 1402
      CNH; CNH domain

    6. XM_028826282.1 → XP_028682115.1  serine/threonine-protein kinase MRCK alpha isoform X18

      UniProtKB/TrEMBL
      G7MEE0, H9ET18
      Conserved Domains (7) summary
      smart00285
      Location:1558 → 1592
      PBD; P21-Rho-binding domain
      COG0419
      Location:432 → 941
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      cd00029
      Location:1000 → 1049
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
      cd01243
      Location:1059 → 1193
      PH_MRCK; MRCK (myotonic dystrophy-related Cdc42-binding kinase) pleckstrin homology (PH) domain
      cd05623
      Location:4 → 412
      STKc_MRCK_alpha; Catalytic domain of the Serine/Threonine Kinase, DMPK-related cell division control protein 42 binding kinase (MRCK) alpha
      pfam00780
      Location:1219 → 1483
      CNH; CNH domain
      pfam15796
      Location:530 → 608
      KELK; KELK-motif containing domain of MRCK Ser/Thr protein kinase

    7. XM_028826197.1 → XP_028682030.1  serine/threonine-protein kinase MRCK alpha isoform X1

      UniProtKB/TrEMBL
      A0A5F8A7D6, G7MEE0
      Related
      ENSMMUP00000073289.1, ENSMMUT00000082895.1
      Conserved Domains (6) summary
      COG0419
      Location:432 → 941
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      cd00029
      Location:1064 → 1113
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
      cd01243
      Location:1123 → 1257
      PH_MRCK; MRCK (myotonic dystrophy-related Cdc42-binding kinase) pleckstrin homology (PH) domain
      cd05623
      Location:4 → 412
      STKc_MRCK_alpha; Catalytic domain of the Serine/Threonine Kinase, DMPK-related cell division control protein 42 binding kinase (MRCK) alpha
      pfam00780
      Location:1283 → 1547
      CNH; CNH domain
      pfam15796
      Location:530 → 608
      KELK; KELK-motif containing domain of MRCK Ser/Thr protein kinase

    8. XM_028826249.1 → XP_028682082.1  serine/threonine-protein kinase MRCK alpha isoform X12

      UniProtKB/TrEMBL
      F7F898, G7MEE0
      Related
      ENSMMUP00000011340.4, ENSMMUT00000012088.4
      Conserved Domains (6) summary
      pfam08826
      Location:800 → 860
      DMPK_coil; DMPK coiled coil domain like
      COG0419
      Location:442 → 860
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      cd00029
      Location:983 → 1032
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
      cd01243
      Location:1042 → 1176
      PH_MRCK; MRCK (myotonic dystrophy-related Cdc42-binding kinase) pleckstrin homology (PH) domain
      cd05623
      Location:4 → 412
      STKc_MRCK_alpha; Catalytic domain of the Serine/Threonine Kinase, DMPK-related cell division control protein 42 binding kinase (MRCK) alpha
      pfam00780
      Location:1202 → 1466
      CNH; CNH domain

    9. XM_028826254.1 → XP_028682087.1  serine/threonine-protein kinase MRCK alpha isoform X13

      UniProtKB/TrEMBL
      G7MEE0
      Conserved Domains (6) summary
      COG0419
      Location:442 → 944
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      cd00029
      Location:980 → 1029
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
      cd01243
      Location:1039 → 1173
      PH_MRCK; MRCK (myotonic dystrophy-related Cdc42-binding kinase) pleckstrin homology (PH) domain
      cd05623
      Location:4 → 412
      STKc_MRCK_alpha; Catalytic domain of the Serine/Threonine Kinase, DMPK-related cell division control protein 42 binding kinase (MRCK) alpha
      pfam00780
      Location:1199 → 1463
      CNH; CNH domain
      pfam15796
      Location:530 → 608
      KELK; KELK-motif containing domain of MRCK Ser/Thr protein kinase

    10. XM_028826230.1 → XP_028682063.1  serine/threonine-protein kinase MRCK alpha isoform X7

      UniProtKB/TrEMBL
      G7MEE0
      Conserved Domains (6) summary
      COG0419
      Location:432 → 941
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      cd00029
      Location:1015 → 1064
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
      cd01243
      Location:1074 → 1208
      PH_MRCK; MRCK (myotonic dystrophy-related Cdc42-binding kinase) pleckstrin homology (PH) domain
      cd05623
      Location:4 → 412
      STKc_MRCK_alpha; Catalytic domain of the Serine/Threonine Kinase, DMPK-related cell division control protein 42 binding kinase (MRCK) alpha
      pfam00780
      Location:1234 → 1498
      CNH; CNH domain
      pfam15796
      Location:530 → 608
      KELK; KELK-motif containing domain of MRCK Ser/Thr protein kinase

    11. XM_028826247.1 → XP_028682080.1  serine/threonine-protein kinase MRCK alpha isoform X10

      UniProtKB/TrEMBL
      F7F8H6, G7MEE0
      Related
      ENSMMUP00000011339.4, ENSMMUT00000012087.4
      Conserved Domains (6) summary
      COG0419
      Location:432 → 941
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      cd00029
      Location:1000 → 1049
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
      cd01243
      Location:1059 → 1193
      PH_MRCK; MRCK (myotonic dystrophy-related Cdc42-binding kinase) pleckstrin homology (PH) domain
      cd05623
      Location:4 → 412
      STKc_MRCK_alpha; Catalytic domain of the Serine/Threonine Kinase, DMPK-related cell division control protein 42 binding kinase (MRCK) alpha
      pfam00780
      Location:1219 → 1483
      CNH; CNH domain
      pfam15796
      Location:530 → 608
      KELK; KELK-motif containing domain of MRCK Ser/Thr protein kinase

    12. XM_028826211.1 → XP_028682044.1  serine/threonine-protein kinase MRCK alpha isoform X4

      UniProtKB/TrEMBL
      A0A5F8AQ75, G7MEE0
      Related
      ENSMMUP00000079991.1, ENSMMUT00000104959.1
      Conserved Domains (6) summary
      COG0419
      Location:432 → 941
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      cd00029
      Location:1035 → 1084
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
      cd01243
      Location:1094 → 1228
      PH_MRCK; MRCK (myotonic dystrophy-related Cdc42-binding kinase) pleckstrin homology (PH) domain
      cd05623
      Location:4 → 412
      STKc_MRCK_alpha; Catalytic domain of the Serine/Threonine Kinase, DMPK-related cell division control protein 42 binding kinase (MRCK) alpha
      pfam00780
      Location:1254 → 1518
      CNH; CNH domain
      pfam15796
      Location:530 → 608
      KELK; KELK-motif containing domain of MRCK Ser/Thr protein kinase

    13. XM_028826239.1 → XP_028682072.1  serine/threonine-protein kinase MRCK alpha isoform X8

      UniProtKB/TrEMBL
      G7MEE0
      Conserved Domains (6) summary
      COG0419
      Location:432 → 941
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      cd00029
      Location:1013 → 1062
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
      cd01243
      Location:1072 → 1206
      PH_MRCK; MRCK (myotonic dystrophy-related Cdc42-binding kinase) pleckstrin homology (PH) domain
      cd05623
      Location:4 → 412
      STKc_MRCK_alpha; Catalytic domain of the Serine/Threonine Kinase, DMPK-related cell division control protein 42 binding kinase (MRCK) alpha
      pfam00780
      Location:1232 → 1496
      CNH; CNH domain
      pfam15796
      Location:530 → 608
      KELK; KELK-motif containing domain of MRCK Ser/Thr protein kinase

    14. XM_028826204.1 → XP_028682037.1  serine/threonine-protein kinase MRCK alpha isoform X3

      UniProtKB/TrEMBL
      A0A5F8A7X6, G7MEE0
      Related
      ENSMMUP00000073067.1, ENSMMUT00000097214.1
      Conserved Domains (6) summary
      COG0419
      Location:432 → 941
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      cd00029
      Location:1048 → 1097
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
      cd01243
      Location:1107 → 1241
      PH_MRCK; MRCK (myotonic dystrophy-related Cdc42-binding kinase) pleckstrin homology (PH) domain
      cd05623
      Location:4 → 412
      STKc_MRCK_alpha; Catalytic domain of the Serine/Threonine Kinase, DMPK-related cell division control protein 42 binding kinase (MRCK) alpha
      pfam00780
      Location:1267 → 1531
      CNH; CNH domain
      pfam15796
      Location:530 → 608
      KELK; KELK-motif containing domain of MRCK Ser/Thr protein kinase

    15. XM_028826222.1 → XP_028682055.1  serine/threonine-protein kinase MRCK alpha isoform X6

      UniProtKB/TrEMBL
      F7HMH4, G7MEE0
      Related
      ENSMMUP00000010993.4, ENSMMUT00000011723.4
      Conserved Domains (6) summary
      COG0419
      Location:432 → 941
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      cd00029
      Location:1016 → 1065
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
      cd01243
      Location:1075 → 1209
      PH_MRCK; MRCK (myotonic dystrophy-related Cdc42-binding kinase) pleckstrin homology (PH) domain
      cd05623
      Location:4 → 412
      STKc_MRCK_alpha; Catalytic domain of the Serine/Threonine Kinase, DMPK-related cell division control protein 42 binding kinase (MRCK) alpha
      pfam00780
      Location:1235 → 1499
      CNH; CNH domain
      pfam15796
      Location:530 → 608
      KELK; KELK-motif containing domain of MRCK Ser/Thr protein kinase

    16. XM_028826202.1 → XP_028682035.1  serine/threonine-protein kinase MRCK alpha isoform X2

      UniProtKB/TrEMBL
      A0A5F7ZY15, G7MEE0
      Related
      ENSMMUP00000070524.1, ENSMMUT00000103211.1
      Conserved Domains (6) summary
      COG0419
      Location:432 → 941
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      cd00029
      Location:1051 → 1100
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
      cd01243
      Location:1110 → 1244
      PH_MRCK; MRCK (myotonic dystrophy-related Cdc42-binding kinase) pleckstrin homology (PH) domain
      cd05623
      Location:4 → 412
      STKc_MRCK_alpha; Catalytic domain of the Serine/Threonine Kinase, DMPK-related cell division control protein 42 binding kinase (MRCK) alpha
      pfam00780
      Location:1270 → 1534
      CNH; CNH domain
      pfam15796
      Location:530 → 608
      KELK; KELK-motif containing domain of MRCK Ser/Thr protein kinase

    17. XM_028826215.1 → XP_028682048.1  serine/threonine-protein kinase MRCK alpha isoform X5

      UniProtKB/TrEMBL
      F7GKE6, G7MEE0
      Related
      ENSMMUP00000038445.3, ENSMMUT00000045417.3
      Conserved Domains (6) summary
      COG0419
      Location:432 → 941
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      cd00029
      Location:1029 → 1078
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
      cd01243
      Location:1088 → 1222
      PH_MRCK; MRCK (myotonic dystrophy-related Cdc42-binding kinase) pleckstrin homology (PH) domain
      cd05623
      Location:4 → 412
      STKc_MRCK_alpha; Catalytic domain of the Serine/Threonine Kinase, DMPK-related cell division control protein 42 binding kinase (MRCK) alpha
      pfam00780
      Location:1248 → 1512
      CNH; CNH domain
      pfam15796
      Location:530 → 608
      KELK; KELK-motif containing domain of MRCK Ser/Thr protein kinase

    18. XM_028826270.1 → XP_028682103.1  serine/threonine-protein kinase MRCK alpha isoform X15

      UniProtKB/TrEMBL
      F7F892
      Related
      ENSMMUP00000011341.4, ENSMMUT00000012089.4
      Conserved Domains (7) summary
      COG0419
      Location:328 → 837
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      cd00029
      Location:960 → 1009
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
      cd00132
      Location:1516 → 1543
      CRIB; PAK (p21 activated kinase) Binding Domain (PBD), binds Cdc42p- and/or Rho-like small GTPases; also known as the Cdc42/Rac interactive binding (CRIB) motif; has been shown to inhibit transcriptional activation and cell transformation mediated by the ...
      cd01243
      Location:1019 → 1153
      PH_MRCK; MRCK (myotonic dystrophy-related Cdc42-binding kinase) pleckstrin homology (PH) domain
      cd05597
      Location:1 → 301
      STKc_DMPK_like; Catalytic domain of Myotonic Dystrophy protein kinase (DMPK)-like Serine/Threonine Kinases
      pfam00780
      Location:1179 → 1443
      CNH; CNH domain
      pfam15796
      Location:426 → 504
      KELK; KELK-motif containing domain of MRCK Ser/Thr protein kinase

    19. XM_028826277.1 → XP_028682110.1  serine/threonine-protein kinase MRCK alpha isoform X17

      UniProtKB/TrEMBL
      G7MEE0
      Conserved Domains (6) summary
      COG0419
      Location:432 → 941
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      cd00029
      Location:1064 → 1113
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
      cd01243
      Location:1123 → 1257
      PH_MRCK; MRCK (myotonic dystrophy-related Cdc42-binding kinase) pleckstrin homology (PH) domain
      cd05623
      Location:4 → 412
      STKc_MRCK_alpha; Catalytic domain of the Serine/Threonine Kinase, DMPK-related cell division control protein 42 binding kinase (MRCK) alpha
      pfam00780
      Location:1283 → 1547
      CNH; CNH domain
      pfam15796
      Location:530 → 608
      KELK; KELK-motif containing domain of MRCK Ser/Thr protein kinase

    20. XM_028826248.1 → XP_028682081.1  serine/threonine-protein kinase MRCK alpha isoform X11

      UniProtKB/TrEMBL
      G7MEE0
      Conserved Domains (6) summary
      COG0419
      Location:432 → 941
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      cd00029
      Location:1064 → 1113
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
      cd01243
      Location:1123 → 1257
      PH_MRCK; MRCK (myotonic dystrophy-related Cdc42-binding kinase) pleckstrin homology (PH) domain
      cd05623
      Location:4 → 412
      STKc_MRCK_alpha; Catalytic domain of the Serine/Threonine Kinase, DMPK-related cell division control protein 42 binding kinase (MRCK) alpha
      pfam00780
      Location:1283 → 1547
      CNH; CNH domain
      pfam15796
      Location:530 → 608
      KELK; KELK-motif containing domain of MRCK Ser/Thr protein kinase

    21. XM_028826290.1 → XP_028682123.1  serine/threonine-protein kinase MRCK alpha isoform X20

      UniProtKB/TrEMBL
      G7MEE0
      Conserved Domains (6) summary
      COG0419
      Location:432 → 941
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      cd00029
      Location:1064 → 1113
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
      cd01243
      Location:1123 → 1257
      PH_MRCK; MRCK (myotonic dystrophy-related Cdc42-binding kinase) pleckstrin homology (PH) domain
      cd05623
      Location:4 → 412
      STKc_MRCK_alpha; Catalytic domain of the Serine/Threonine Kinase, DMPK-related cell division control protein 42 binding kinase (MRCK) alpha
      pfam00780
      Location:1283 → 1547
      CNH; CNH domain
      pfam15796
      Location:530 → 608
      KELK; KELK-motif containing domain of MRCK Ser/Thr protein kinase

    22. XM_028826300.1 → XP_028682133.1  serine/threonine-protein kinase MRCK alpha isoform X22

      UniProtKB/TrEMBL
      G7MEE0
      Conserved Domains (6) summary
      COG0419
      Location:432 → 941
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      cd00029
      Location:1064 → 1113
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
      cd01243
      Location:1123 → 1257
      PH_MRCK; MRCK (myotonic dystrophy-related Cdc42-binding kinase) pleckstrin homology (PH) domain
      cd05623
      Location:4 → 412
      STKc_MRCK_alpha; Catalytic domain of the Serine/Threonine Kinase, DMPK-related cell division control protein 42 binding kinase (MRCK) alpha
      pfam00780
      Location:1283 → 1547
      CNH; CNH domain
      pfam15796
      Location:530 → 608
      KELK; KELK-motif containing domain of MRCK Ser/Thr protein kinase

    RNA

    1. XR_003719281.1 RNA Sequence

    2. XR_003719268.1 RNA Sequence

    3. XR_003719269.1 RNA Sequence

    4. XR_003719251.1 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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