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    ASB2 ankyrin repeat and SOCS box containing 2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 699882, updated on 17-Aug-2024

    Summary

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    Official Symbol
    ASB2provided by VGNC
    Official Full Name
    ankyrin repeat and SOCS box containing 2provided by VGNC
    Primary source
    VGNC:VGNC:69840
    See related
    Ensembl:ENSMMUG00000012400
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See ASB2 in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 7 NC_041760.1 (156093459..156137070, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 7 NC_027899.1 (156175039..156218723, complement)

    Chromosome 7 - NC_041760.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106999530 Neighboring gene family with sequence similarity 181 member A Neighboring gene uncharacterized LOC114679629 Neighboring gene coiled-coil domain containing 197 Neighboring gene OTU deubiquitinase, ubiquitin aldehyde binding 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ankyrin repeat and SOCS box protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041760.1 Reference Mmul_10 Primary Assembly

      Range
      156093459..156137070 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015144411.2 → XP_014999897.1  ankyrin repeat and SOCS box protein 2 isoform X2

      UniProtKB/TrEMBL
      F7EA98
      Related
      ENSMMUP00000016283.3, ENSMMUT00000017387.4
      Conserved Domains (4) summary
      PHA02876
      Location:165 → 469
      PHA02876; ankyrin repeat protein; Provisional
      cd03721
      Location:591 → 635
      SOCS_ASB2; SOCS (suppressors of cytokine signaling) box of ASB2-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. ASB2 targets specific proteins to destruction by the proteasome in leukemia cells that have been ...
      sd00045
      Location:237 → 268
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:109 → 202
      Ank_2; Ankyrin repeats (3 copies)

    2. XM_028851780.1 → XP_028707613.1  ankyrin repeat and SOCS box protein 2 isoform X2

      UniProtKB/TrEMBL
      F7EA98
      Conserved Domains (4) summary
      PHA02876
      Location:165 → 469
      PHA02876; ankyrin repeat protein; Provisional
      cd03721
      Location:591 → 635
      SOCS_ASB2; SOCS (suppressors of cytokine signaling) box of ASB2-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. ASB2 targets specific proteins to destruction by the proteasome in leukemia cells that have been ...
      sd00045
      Location:237 → 268
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:109 → 202
      Ank_2; Ankyrin repeats (3 copies)

    3. XM_028851779.1 → XP_028707612.1  ankyrin repeat and SOCS box protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A5F8AI03
      Related
      ENSMMUP00000076620.1, ENSMMUT00000079649.1
      Conserved Domains (4) summary
      PHA02876
      Location:320 → 624
      PHA02876; ankyrin repeat protein; Provisional
      sd00045
      Location:392 → 423
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:264 → 357
      Ank_2; Ankyrin repeats (3 copies)
      cl02533
      Location:746 → 790
      SOCS; SOCS (suppressors of cytokine signaling) box. The SOCS box is found in the C-terminal region of CIS/SOCS family proteins (in combination with a SH2 domain), ASBs (ankyrin repeat-containing proteins with a SOCS box), SSBs (SPRY domain-containing proteins ...
    Nucleotide Protein
    Heading Accession and Version

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