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    CACNB2 calcium voltage-gated channel auxiliary subunit beta 2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 701226, updated on 17-Aug-2024

    Summary

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    Official Symbol
    CACNB2provided by VGNC
    Official Full Name
    calcium voltage-gated channel auxiliary subunit beta 2provided by VGNC
    Primary source
    VGNC:VGNC:70510
    See related
    Ensembl:ENSMMUG00000007445
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See CACNB2 in Genome Data Viewer
    Location:
    chromosome: 9
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 9 NC_041762.1 (19278847..19683711)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 9 NC_027901.1 (18335871..18747133)

    Chromosome 9 - NC_041762.1Genomic Context describing neighboring genes Neighboring gene mannose receptor C-type 1 Neighboring gene microRNA mir-511 Neighboring gene solute carrier family 39 member 12 Neighboring gene uncharacterized LOC107000058 Neighboring gene uncharacterized LOC107000059 Neighboring gene NOP2/Sun RNA methyltransferase 6 Neighboring gene ADP ribosylation factor like GTPase 5B

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables high voltage-gated calcium channel activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in calcium ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in chemical synaptic transmission IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in neuromuscular junction development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of voltage-gated calcium channel activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of voltage-gated calcium channel complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    voltage-dependent L-type calcium channel subunit beta-2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001257782.1 → NP_001244711.1  voltage-dependent L-type calcium channel subunit beta-2

      See identical proteins and their annotated locations for NP_001244711.1

      Status: PROVISIONAL

      Source sequence(s)
      JU322059
      UniProtKB/TrEMBL
      F6SWC7, F6SWF4
      Related
      ENSMMUP00000009776.2, ENSMMUT00000010415.4
      Conserved Domains (4) summary
      cd12040
      Location:64 → 132
      SH3_CACNB2; Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta2
      pfam00625
      Location:232 → 412
      Guanylate_kin; Guanylate kinase
      pfam12052
      Location:24 → 65
      VGCC_beta4Aa_N; Voltage gated calcium channel subunit beta domain 4Aa N terminal
      cl17190
      Location:242 → 413
      NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041762.1 Reference Mmul_10 Primary Assembly

      Range
      19278847..19683711
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015146548.2 → XP_015002034.1  voltage-dependent L-type calcium channel subunit beta-2 isoform X1

      UniProtKB/TrEMBL
      F6SWI4, G7N1P3
      Related
      ENSMMUP00000009770.2, ENSMMUT00000010409.4
      Conserved Domains (4) summary
      cd12040
      Location:112 → 180
      SH3_CACNB2; Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta2
      pfam00625
      Location:280 → 460
      Guanylate_kin; Guanylate kinase
      pfam12052
      Location:72 → 113
      VGCC_beta4Aa_N; Voltage gated calcium channel subunit beta domain 4Aa N terminal
      cl17190
      Location:290 → 461
      NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...

    2. XM_015146551.2 → XP_015002037.1  voltage-dependent L-type calcium channel subunit beta-2 isoform X3

      UniProtKB/TrEMBL
      G7N1P3
      Conserved Domains (4) summary
      cd12040
      Location:112 → 180
      SH3_CACNB2; Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta2
      pfam00625
      Location:242 → 422
      Guanylate_kin; Guanylate kinase
      pfam12052
      Location:72 → 113
      VGCC_beta4Aa_N; Voltage gated calcium channel subunit beta domain 4Aa N terminal
      cl17190
      Location:252 → 423
      NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...

    3. XM_015146549.2 → XP_015002035.1  voltage-dependent L-type calcium channel subunit beta-2 isoform X9

      UniProtKB/TrEMBL
      G7N1P3
      Conserved Domains (4) summary
      cd12040
      Location:112 → 180
      SH3_CACNB2; Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta2
      pfam00625
      Location:256 → 436
      Guanylate_kin; Guanylate kinase
      pfam12052
      Location:72 → 113
      VGCC_beta4Aa_N; Voltage gated calcium channel subunit beta domain 4Aa N terminal
      cl17190
      Location:266 → 437
      NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...

    4. XM_015146550.2 → XP_015002036.1  voltage-dependent L-type calcium channel subunit beta-2 isoform X2

      UniProtKB/TrEMBL
      G7N1P3
      Conserved Domains (4) summary
      cd12040
      Location:84 → 152
      SH3_CACNB2; Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta2
      pfam00625
      Location:252 → 432
      Guanylate_kin; Guanylate kinase
      pfam12052
      Location:44 → 85
      VGCC_beta4Aa_N; Voltage gated calcium channel subunit beta domain 4Aa N terminal
      cl17190
      Location:262 → 433
      NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...

    5. XM_015146555.2 → XP_015002041.1  voltage-dependent L-type calcium channel subunit beta-2 isoform X6

      UniProtKB/TrEMBL
      G7N1P3
      Conserved Domains (4) summary
      cd12040
      Location:84 → 152
      SH3_CACNB2; Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta2
      pfam00625
      Location:214 → 394
      Guanylate_kin; Guanylate kinase
      pfam12052
      Location:44 → 85
      VGCC_beta4Aa_N; Voltage gated calcium channel subunit beta domain 4Aa N terminal
      cl17190
      Location:224 → 395
      NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...

    6. XM_015146552.2 → XP_015002038.1  voltage-dependent L-type calcium channel subunit beta-2 isoform X10

      UniProtKB/TrEMBL
      F6SWH6
      Related
      ENSMMUP00000009771.3, ENSMMUT00000010410.4
      Conserved Domains (4) summary
      cd12040
      Location:84 → 152
      SH3_CACNB2; Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta2
      pfam00625
      Location:228 → 408
      Guanylate_kin; Guanylate kinase
      pfam12052
      Location:44 → 85
      VGCC_beta4Aa_N; Voltage gated calcium channel subunit beta domain 4Aa N terminal
      cl17190
      Location:238 → 409
      NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...

    7. XM_015146558.2 → XP_015002044.1  voltage-dependent L-type calcium channel subunit beta-2 isoform X8

      UniProtKB/TrEMBL
      F6SWH6
      Conserved Domains (3) summary
      cd12040
      Location:57 → 125
      SH3_CACNB2; Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta2
      pfam00625
      Location:187 → 367
      Guanylate_kin; Guanylate kinase
      pfam12052
      Location:17 → 58
      VGCC_beta4Aa_N; Voltage gated calcium channel subunit beta domain 4Aa N terminal

    8. XM_015146554.2 → XP_015002040.1  voltage-dependent L-type calcium channel subunit beta-2 isoform X5

      UniProtKB/TrEMBL
      F6SWD8, F6SWF4
      Related
      ENSMMUP00000009775.4, ENSMMUT00000010414.4
      Conserved Domains (3) summary
      cd12040
      Location:57 → 125
      SH3_CACNB2; Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta2
      pfam00625
      Location:225 → 405
      Guanylate_kin; Guanylate kinase
      pfam12052
      Location:17 → 58
      VGCC_beta4Aa_N; Voltage gated calcium channel subunit beta domain 4Aa N terminal

    9. XM_015146553.2 → XP_015002039.1  voltage-dependent L-type calcium channel subunit beta-2 isoform X4

      UniProtKB/TrEMBL
      F6SWF4, F7GXI1
      Related
      ENSMMUP00000036191.2, ENSMMUT00000043181.3
      Conserved Domains (4) summary
      cd12040
      Location:58 → 126
      SH3_CACNB2; Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta2
      pfam00625
      Location:226 → 406
      Guanylate_kin; Guanylate kinase
      pfam12052
      Location:18 → 59
      VGCC_beta4Aa_N; Voltage gated calcium channel subunit beta domain 4Aa N terminal
      cl17190
      Location:236 → 407
      NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...

    10. XM_015146557.2 → XP_015002043.1  voltage-dependent L-type calcium channel subunit beta-2 isoform X7

      UniProtKB/TrEMBL
      A0A1D5R992, F6SWH6
      Related
      ENSMMUP00000056883.2, ENSMMUT00000056176.2
      Conserved Domains (4) summary
      cd12040
      Location:64 → 132
      SH3_CACNB2; Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta2
      pfam00625
      Location:194 → 374
      Guanylate_kin; Guanylate kinase
      pfam12052
      Location:24 → 65
      VGCC_beta4Aa_N; Voltage gated calcium channel subunit beta domain 4Aa N terminal
      cl17190
      Location:204 → 375
      NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...
    Nucleotide Protein
    Heading Accession and Version

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