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    ARHGAP10 Rho GTPase activating protein 10 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 708458, updated on 17-Aug-2024

    Summary

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    Official Symbol
    ARHGAP10provided by VGNC
    Official Full Name
    Rho GTPase activating protein 10provided by VGNC
    Primary source
    VGNC:VGNC:69914
    See related
    Ensembl:ENSMMUG00000014953
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See ARHGAP10 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    27
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 5 NC_041758.1 (145329655..145680099)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 5 NC_027897.1 (147582302..147933259)

    Chromosome 5 - NC_041758.1Genomic Context describing neighboring genes Neighboring gene transmembrane protein 184C Neighboring gene protein arginine methyltransferase 9 Neighboring gene U6 spliceosomal RNA Neighboring gene nuclear receptor subfamily 3 group C member 2 Neighboring gene uncharacterized LOC106998533

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables GTPase activator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    rho GTPase-activating protein 10

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041758.1 Reference Mmul_10 Primary Assembly

      Range
      145329655..145680099
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028848805.1 → XP_028704638.1  rho GTPase-activating protein 10 isoform X7

      UniProtKB/TrEMBL
      A0A5F8AP02
      Conserved Domains (3) summary
      cd04374
      Location:378 → 590
      RhoGAP_Graf; GTPase-activator protein (GAP) domain for Rho-like GTPases found in GRAF (GTPase regulator associated with focal adhesion kinase); Graf is a multi-domain protein, containing SH3 and PH domains, that binds focal adhesion kinase and influences cytoskeletal ...
      cd01249
      Location:278 → 385
      BAR-PH_GRAF_family; GTPase Regulator Associated with Focal adhesion and related proteins Pleckstrin homology (PH) domain
      cl12013
      Location:64 → 236
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

    2. XM_028848803.1 → XP_028704636.1  rho GTPase-activating protein 10 isoform X5

      UniProtKB/TrEMBL
      A0A5F8AP02
      Conserved Domains (4) summary
      cd12065
      Location:702 → 755
      SH3_GRAF2; Src Homology 3 domain of GTPase Regulator Associated with Focal adhesion kinase 2
      cd04374
      Location:378 → 590
      RhoGAP_Graf; GTPase-activator protein (GAP) domain for Rho-like GTPases found in GRAF (GTPase regulator associated with focal adhesion kinase); Graf is a multi-domain protein, containing SH3 and PH domains, that binds focal adhesion kinase and influences cytoskeletal ...
      cd01249
      Location:278 → 385
      BAR-PH_GRAF_family; GTPase Regulator Associated with Focal adhesion and related proteins Pleckstrin homology (PH) domain
      cl12013
      Location:64 → 236
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

    3. XM_028848801.1 → XP_028704634.1  rho GTPase-activating protein 10 isoform X1

      UniProtKB/TrEMBL
      F6VTW2
      Conserved Domains (5) summary
      cd12065
      Location:753 → 806
      SH3_GRAF2; Src Homology 3 domain of GTPase Regulator Associated with Focal adhesion kinase 2
      cd04374
      Location:378 → 590
      RhoGAP_Graf; GTPase-activator protein (GAP) domain for Rho-like GTPases found in GRAF (GTPase regulator associated with focal adhesion kinase); Graf is a multi-domain protein, containing SH3 and PH domains, that binds focal adhesion kinase and influences cytoskeletal ...
      cd01249
      Location:278 → 385
      BAR-PH_GRAF_family; GTPase Regulator Associated with Focal adhesion and related proteins Pleckstrin homology (PH) domain
      pfam03154
      Location:598 → 755
      Atrophin-1; Atrophin-1 family
      cl12013
      Location:64 → 236
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

    4. XM_028848804.1 → XP_028704637.1  rho GTPase-activating protein 10 isoform X6

      UniProtKB/TrEMBL
      A0A5F8AP02
      Conserved Domains (4) summary
      cd12065
      Location:692 → 745
      SH3_GRAF2; Src Homology 3 domain of GTPase Regulator Associated with Focal adhesion kinase 2
      cd04374
      Location:378 → 580
      RhoGAP_Graf; GTPase-activator protein (GAP) domain for Rho-like GTPases found in GRAF (GTPase regulator associated with focal adhesion kinase); Graf is a multi-domain protein, containing SH3 and PH domains, that binds focal adhesion kinase and influences cytoskeletal ...
      cd01249
      Location:278 → 385
      BAR-PH_GRAF_family; GTPase Regulator Associated with Focal adhesion and related proteins Pleckstrin homology (PH) domain
      cl12013
      Location:64 → 236
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

    5. XM_015139310.2 → XP_014994796.2  rho GTPase-activating protein 10 isoform X2

      UniProtKB/TrEMBL
      F6VTW2
      Conserved Domains (5) summary
      cd12065
      Location:743 → 796
      SH3_GRAF2; Src Homology 3 domain of GTPase Regulator Associated with Focal adhesion kinase 2
      cd04374
      Location:378 → 580
      RhoGAP_Graf; GTPase-activator protein (GAP) domain for Rho-like GTPases found in GRAF (GTPase regulator associated with focal adhesion kinase); Graf is a multi-domain protein, containing SH3 and PH domains, that binds focal adhesion kinase and influences cytoskeletal ...
      cd01249
      Location:278 → 385
      BAR-PH_GRAF_family; GTPase Regulator Associated with Focal adhesion and related proteins Pleckstrin homology (PH) domain
      pfam03154
      Location:588 → 745
      Atrophin-1; Atrophin-1 family
      cl12013
      Location:64 → 236
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

    6. XM_028848802.1 → XP_028704635.1  rho GTPase-activating protein 10 isoform X3

      UniProtKB/TrEMBL
      F6VTW2
      Conserved Domains (5) summary
      cd07635
      Location:19 → 225
      BAR_GRAF2; The Bin/Amphiphysin/Rvs (BAR) domain of GTPase Regulator Associated with Focal adhesion 2
      cd12065
      Location:742 → 795
      SH3_GRAF2; Src Homology 3 domain of GTPase Regulator Associated with Focal adhesion kinase 2
      cd04374
      Location:367 → 579
      RhoGAP_Graf; GTPase-activator protein (GAP) domain for Rho-like GTPases found in GRAF (GTPase regulator associated with focal adhesion kinase); Graf is a multi-domain protein, containing SH3 and PH domains, that binds focal adhesion kinase and influences cytoskeletal ...
      cd01249
      Location:267 → 374
      BAR-PH_GRAF_family; GTPase Regulator Associated with Focal adhesion and related proteins Pleckstrin homology (PH) domain
      pfam03154
      Location:587 → 744
      Atrophin-1; Atrophin-1 family

    7. XM_015139311.2 → XP_014994797.2  rho GTPase-activating protein 10 isoform X4

      UniProtKB/TrEMBL
      A0A5S6RDF0, A0A8J8YD40, F6VTW2, F7HUG9, G7MS36
      Related
      ENSMMUP00000034718.3, ENSMMUT00000041697.3
      Conserved Domains (5) summary
      cd07635
      Location:19 → 225
      BAR_GRAF2; The Bin/Amphiphysin/Rvs (BAR) domain of GTPase Regulator Associated with Focal adhesion 2
      cd12065
      Location:732 → 785
      SH3_GRAF2; Src Homology 3 domain of GTPase Regulator Associated with Focal adhesion kinase 2
      cd04374
      Location:367 → 569
      RhoGAP_Graf; GTPase-activator protein (GAP) domain for Rho-like GTPases found in GRAF (GTPase regulator associated with focal adhesion kinase); Graf is a multi-domain protein, containing SH3 and PH domains, that binds focal adhesion kinase and influences cytoskeletal ...
      cd01249
      Location:267 → 374
      BAR-PH_GRAF_family; GTPase Regulator Associated with Focal adhesion and related proteins Pleckstrin homology (PH) domain
      pfam03154
      Location:577 → 734
      Atrophin-1; Atrophin-1 family

    8. XM_028848806.1 → XP_028704639.1  rho GTPase-activating protein 10 isoform X8

      UniProtKB/TrEMBL
      F6VTW2
      Conserved Domains (5) summary
      cd12065
      Location:639 → 692
      SH3_GRAF2; Src Homology 3 domain of GTPase Regulator Associated with Focal adhesion kinase 2
      cd04374
      Location:264 → 476
      RhoGAP_Graf; GTPase-activator protein (GAP) domain for Rho-like GTPases found in GRAF (GTPase regulator associated with focal adhesion kinase); Graf is a multi-domain protein, containing SH3 and PH domains, that binds focal adhesion kinase and influences cytoskeletal ...
      cd01249
      Location:164 → 271
      BAR-PH_GRAF_family; GTPase Regulator Associated with Focal adhesion and related proteins Pleckstrin homology (PH) domain
      pfam03154
      Location:484 → 641
      Atrophin-1; Atrophin-1 family
      cl12013
      Location:1 → 122
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
    Nucleotide Protein
    Heading Accession and Version

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