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    F10 coagulation factor X [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 714132, updated on 17-Aug-2024

    Summary

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    Official Symbol
    F10provided by VGNC
    Official Full Name
    coagulation factor Xprovided by VGNC
    Primary source
    VGNC:VGNC:72459
    See related
    Ensembl:ENSMMUG00000001038
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See F10 in Genome Data Viewer
    Location:
    chromosome: 17
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 17 NC_041770.1 (94364899..94392818)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 17 NC_027909.1 (94599283..94627902)

    Chromosome 17 - NC_041770.1Genomic Context describing neighboring genes Neighboring gene MCF.2 cell line derived transforming sequence like Neighboring gene uncharacterized LOC106996652 Neighboring gene uncharacterized LOC114673492 Neighboring gene uncharacterized LOC106994402 Neighboring gene coagulation factor VII Neighboring gene protein Z, vitamin K dependent plasma glycoprotein Neighboring gene PCI domain containing 2 Neighboring gene cullin 4A

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables serine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in blood coagulation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    coagulation factor X
    Names
    coagulation factor X preproprotein
    NP_001098054.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001104584.1 → NP_001098054.1  coagulation factor X precursor

      See identical proteins and their annotated locations for NP_001098054.1

      Status: PROVISIONAL

      Source sequence(s)
      EF057491
      UniProtKB/TrEMBL
      A0N065, F7HM21, I2CVN8
      Related
      ENSMMUP00000036008.3, ENSMMUT00000042996.3
      Conserved Domains (5) summary
      smart00020
      Location:234 → 462
      Tryp_SPc; Trypsin-like serine protease
      smart00069
      Location:22 → 85
      GLA; Domain containing Gla (gamma-carboxyglutamate) residues
      cd00054
      Location:86 → 122
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      cd00190
      Location:235 → 464
      Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
      pfam14670
      Location:129 → 164
      FXa_inhibition; Coagulation Factor Xa inhibitory site

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041770.1 Reference Mmul_10 Primary Assembly

      Range
      94364899..94392818
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

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